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5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE

5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Structure
CAS No.
189744-46-5
Chemical Name:
5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE
Synonyms
RO 10-5824;Ro 10-5824 dihydrochloride;2-methyl-5-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]pyrimidin-4-amine;4-Pyrimidinamine, 5-[(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)methyl]-2-methyl-;5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE
CBNumber:
CB6848552
Molecular Formula:
C17H20N4
Molecular Weight:
280.37
MOL File:
189744-46-5.mol
Modify Date:
2023/5/4 17:34:35
Request For Quotation

5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Properties

Boiling point 456.7±45.0 °C(Predicted)
Density 1.186±0.06 g/cm3(Predicted)
storage temp. Desiccate at RT
pka 6.49±0.40(Predicted)

5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Chemical Properties,Uses,Production

Uses

The dopamine receptors play important role in cognition, memory, learning, and motor control (1). These receptors have been implicated as a therapeutic target for many psychiatric and neurological disorders. Ro 10-5824 Dihydrochloride is a selective dopamine D4?receptor partial agonist (2).

Biological Activity

Selective dopamine D 4 receptor partial agonist (EC 50 = 205 nM) that binds with high affinity (K i = 5.2 nM). Displays 250-fold selectivity over D 3 receptors and > 1000-fold selectivity over D 2 , D 1 and D 5 receptors.

5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Suppliers

Global( 28)Suppliers
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TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23963 58 Inquiry
Shanghai Rechem science Co., Ltd. 21-31433387 15618786686 China 2974 58 Inquiry
InvivoChem 13549236410 China 6747 58 Inquiry
Wako Pure Chemical Industries, Ltd. +81 6 6203 3741 Japan 6828 80 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
Shanghai Weiwei Biological Technology Co., Ltd. 021-55669583 18616258598 CHINA 4398 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
InvivoChem 58
TargetMol Chemicals Inc. 58
Shanghai Rechem science Co., Ltd. 58
InvivoChem 58
Wako Pure Chemical Industries, Ltd. 80
Service Chemical Inc. 71
Tocris Bioscience 77
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Shanghai Weiwei Biological Technology Co., Ltd. 58

189744-46-5(5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE)Related Search:

4-Amino-5-aminomethyl-2-methylpyrimidine 5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride
RO 10-5824 5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Ro 10-5824 dihydrochloride 2-methyl-5-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]pyrimidin-4-amine 4-Pyrimidinamine, 5-[(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)methyl]-2-methyl- 189744-46-5 C17H20N42HCl