ChemicalBook > Product Catalog >Pharmaceutical intermediates >Bulk Drug Intermediates >4-Formyl-2-isopropylthiazole
4-Formyl-2-isopropylthiazole
![4-Formyl-2-isopropylthiazole Structure](CAS/GIF/133047-46-8.gif)
- CAS No.
- 133047-46-8
- Chemical Name:
- 4-Formyl-2-isopropylthiazole
- Synonyms
- 4-FORMYL-2-ISOPROPYLTHIAZOLE;2-isopropylthiazol-4-carbaldehyde;2-isopropylthiazole-4-carbaldehyde;2-(1-methylethyl)-4-Thiazolecarboxaldehyde;2-(propan-2-yl)-1,3-thiazole-4-carbaldehyde;4-Thiazolecarboxaldehyde, 2-(1-methylethyl)-;4-Thiazolecarboxaldehyde, 2-(1-methylethyl)- (9CI)
- CBNumber:
- CB71090526
- Molecular Formula:
- C7H9NOS
- Molecular Weight:
- 155.22
- MOL File:
- 133047-46-8.mol
- Modify Date:
- 2023/11/1 9:12:58
Boiling point | 232.4±13.0 °C(Predicted) |
---|---|
Density | 1.159±0.06 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
pka | 1.10±0.10(Predicted) |
InChI | InChI=1S/C7H9NOS/c1-5(2)7-8-6(3-9)4-10-7/h3-5H,1-2H3 |
InChIKey | NUEZKCPTDMEROB-UHFFFAOYSA-N |
SMILES | S1C=C(C=O)N=C1C(C)C |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P280-P305+P351+P338 |
Hazard Codes | Xn |
Risk Statements | 22 |
WGK Germany | 3 |
HS Code | 2934100090 |
4-Formyl-2-isopropylthiazole Chemical Properties,Uses,Production
Synthesis
A solution of 3.1 g (15.6 mmol) of ethyl 2-isopropylthiazole-4-carboxylate in 50 ml of dichloromethane was cooled under N2 atmosphere to -78° C and treated dropwise with 15.6 ml (23.4 mmol) of a 1.5 M solution of diisobutylaluminum hydride in toluene over 1.5 h. After being stirred for an additional 0.5 h, the solution was quenched with 5 ml of methanol followed by 15 ml of aqueous Rochelle's salt. The resulting mixture was partitioned between chloroform and aqueous Rochelle's salt, dried over Na2SO4, and concentrated to provide 1.37 g (56 %) of the crude 4-Formyl-2-isopropylthiazole.
4-Formyl-2-isopropylthiazole Preparation Products And Raw materials
Raw materials
Preparation Products
4-Formyl-2-isopropylthiazole Suppliers
Global( 54)Suppliers
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133047-46-8(4-Formyl-2-isopropylthiazole)Related Search:
4-Thiazolecarboxaldehyde, 2-(1-methylethyl)- (9CI)
2-isopropylthiazole-4-carbaldehyde
2-(propan-2-yl)-1,3-thiazole-4-carbaldehyde
2-isopropylthiazol-4-carbaldehyde
2-(1-methylethyl)-4-Thiazolecarboxaldehyde
4-Thiazolecarboxaldehyde, 2-(1-methylethyl)-
4-FORMYL-2-ISOPROPYLTHIAZOLE
133047-46-8
ALDEHYDE
ISOPROPYL