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Columbin

Columbin Structure
CAS No.
546-97-4
Chemical Name:
Columbin
Synonyms
Tinosporin;Columbin USP/EP/BP;Columbin >=95% (LC/MS-ELSD);Columbin, 98%, from limacia sagittata;(1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione;(1s,2s,3s,5s,8r,11r,12s)-5-(3-furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione;(1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione;diterpenoid,Cyclooxygenase,anti-inflammatory,COX-1,Inhibitor,Trypanosoma brucei,Columbin,furanolactone,COX,anti-trypanosomal,Parasite,inhibit;(1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione;(1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione
CBNumber:
CB71246910
Molecular Formula:
C20H22O6
Molecular Weight:
358.39
MOL File:
546-97-4.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:15

Columbin Properties

Melting point 190-191℃
alpha D +52.5° (pyridine)
Boiling point 410.82°C (rough estimate)
Density 1.36
refractive index 1.4450 (estimate)
storage temp. -20°C
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 0.03 mg/ml
form Cryst.
pka 12.14±0.70(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  29322090

Columbin price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) SMB00086 Columbin ≥95% (LC/MS-ELSD) 546-97-4 1MG ₹24518.63 2022-06-14 Buy
Product number Packaging Price Buy
SMB00086 1MG ₹24518.63 Buy

Columbin Chemical Properties,Uses,Production

Uses

Columbin is a furanolactone diterpene isolated from the roots of Jateorhiza and Tinospora species and is used in Asian and African folk medicine for analgesic and antipyretic properties.

Columbin Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 118)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Chengdu GLP biotechnology Co Ltd 028-87075086 13350802083 CHINA 1824 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +8618080483897 China 3777 58 Inquiry
Shaanxi Pioneer Biotech Co., Ltd . +8613259417953 China 3000 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Neostar United (Changzhou) Industrial Co., Ltd. +86-519-519-85557386 China 11506 58 Inquiry
Hubei Ipure Biology Co., Ltd +8613367258412 China 10326 58 Inquiry
Apeloa Pharmaceutical Co., Ltd. +86-0571-87635730 +8615858229168 China 1478 58 Inquiry
ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23556 58 Inquiry
(1s,2s,3s,5s,8r,11r,12s)-5-(3-furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione (1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione (1R,4R,4aR,6aR,9S,10aS,10bS)-9-(3-Furanyl)decahydro-4-hydroxy-4a,10a-dimethyl-1,4-etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione Tinosporin Columbin, 98%, from limacia sagittata (1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione (1R,2S,3S,5S,8R,11R,12R)-5-(3-Furyl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione 1,4-Etheno-3H,7H-benzo[1,2-c:3,4-c']dipyran-3,7-dione, 9-(3-furanyl)-1,4,4a,5,6,6a,9,10,10a,10b-decahydro-4-hydroxy-4a,10a-dimethyl-, (1R,4R,4aR,6aR,9S,10aS,10bS)- Columbin >=95% (LC/MS-ELSD) Columbin USP/EP/BP (2S,4AR,6aR,7R,10R,10aS,10bS)-2-(furan-3-yl)-7-hydroxy-6a,10b-dimethyl-4a,5,6,6a,7,10,10a,10b-octahydro-1H-10,7-(epoxymethano)benzo[f]isochromene-4,12(2H)-dione diterpenoid,Cyclooxygenase,anti-inflammatory,COX-1,Inhibitor,Trypanosoma brucei,Columbin,furanolactone,COX,anti-trypanosomal,Parasite,inhibit 546-97-4 Miscellaneous Natural Products