10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE

10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE Structure
CAS No.
39654-52-9
Chemical Name:
10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE
Synonyms
Cyclobenzaprine Impurity 2;Cyclobenzaprine Impurity 12;TRANS-10,11-DIBROMODIBENZOSUBERONE;10,11-Dibromo10,11-dihydro-5-dibenzosuberenone;10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE;5H-Dibenzo[a,d]cyclohepten-5-one,10,11-dibromo-10,11-dihydro-, (10R,11R)-rel-
CBNumber:
CB7128611
Molecular Formula:
C15H10Br2O
Molecular Weight:
366.05
MOL File:
39654-52-9.mol
MSDS File:
SDS
Modify Date:
2023/7/15 8:28:15

10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE Properties

Melting point 213 °C (dec.)(lit.)
Boiling point 395.6±42.0 °C(Predicted)
Density 1.751±0.06 g/cm3(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H319-H335-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39
WGK Germany  3

10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE Chemical Properties,Uses,Production

Uses

10,11-Dibromo10,11-dihydro-5-dibenzosuberenone is an intermediate in the synthesis of 10-Hydroxy (E)-Amitriptyline (D462790). (5E)-5-[3-(dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol is a metabolite of amitriptyline (A633350) which is a dibenzocycloheptadiene derivative and an antidepressant (1). Amitriptyline is also a TrkA and TrkB receptor agonist and exhibits neurotrophic and anti-inflammatory activities (2,3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA).

10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE Suppliers

10,11-DIBROMO-10,11-DIHYDRO-5H-DIBENZO[A,D]CYCLOHEPTEN-5-ONE TRANS-10,11-DIBROMODIBENZOSUBERONE 5H-Dibenzo[a,d]cyclohepten-5-one,10,11-dibromo-10,11-dihydro-, (10R,11R)-rel- Cyclobenzaprine Impurity 2 10,11-Dibromo10,11-dihydro-5-dibenzosuberenone Cyclobenzaprine Impurity 12 39654-52-9 Organic Building Blocks Ketones Building Blocks C15 to C38 Carbonyl Compounds