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S-Trityl-L-cysteine

S-Trityl-L-cysteine Structure
CAS No.
2799-07-7
Chemical Name:
S-Trityl-L-cysteine
Synonyms
H-CYS(TRT)-OH;Dimethyl 5-bromopyridine-2,3-dicarboxylate;H-L-Cys(Trt)-OH;S-Tritylcysteine;H-Cys(Trt)-OH (Cys of Animal Origin);NSC 83265;L-Cys(Trt)-OH;CYSTEINE(TRT)-OH;EG5 INHIBITOR II;TRITYL-L-CYSTEINE
CBNumber:
CB7164332
Molecular Formula:
C22H21NO2S
Molecular Weight:
363.47
MOL File:
2799-07-7.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59

S-Trityl-L-cysteine Properties

Melting point 182-183 °C (dec.)(lit.)
Boiling point 524.7±50.0 °C(Predicted)
Density 1.1342 (rough estimate)
refractive index 111 ° (C=0.8, 0.04mol Ethanolic HCl)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in DMSO (up to 20 mg/ml).
form White to off-white solid.
pka 2.22±0.10(Predicted)
color White or off-white
optical activity [α]25/D +115°, c = 0.8 in 0.04 M ethanolic HCl
BRN 2339626
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 week.
CAS DataBase Reference 2799-07-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312+P330-P501-P301+P312a-P330-P501a
Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-24/25
WGK Germany  3
RTECS  AY7710000
HS Code  29309090
Toxicity dog,LDLo,intravenous,150mg/kg (150mg/kg),GASTROINTESTINAL: NAUSEA OR VOMITINGGASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY),National Technical Information Service. Vol. PB81-109993,
NFPA 704
1
1 0

S-Trityl-L-cysteine price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 164739 (+)-S-Trityl-L-cysteine 97% 2799-07-7 5G ₹9937.35 2022-06-14 Buy
TCI Chemicals (India) T2522 S-Trityl-L-cysteine 2799-07-7 5G ₹3200 2022-05-26 Buy
SRL 48445 S-Trityl-L-Cysteine extrapure, 98% 2799-07-7 1Gms ₹4510 2022-05-26 Buy
Product number Packaging Price Buy
164739 5G ₹9937.35 Buy
T2522 5G ₹3200 Buy
48445 1Gms ₹4510 Buy

S-Trityl-L-cysteine Chemical Properties,Uses,Production

Chemical Properties

almost white to light yellow granular powder

Uses

A protected cysteine for peptide synthesis. S-Trityl-L-cysteine (STLC) is a tight-binding inhibitor of Eg5 that prevents mitotic progression. It has proven antitumor activity as shown in the NCI 60 tumor cell line screen.

Biological Activity

Potent, cell-permeable, selective inhibitor of mitotic kinesin Eg5, a protein required for establishing and maintaining a bipolar spindle. Inhibits basal ATPase activity (IC 50 = 1 mM) and microtubule-activated ATPase activity of Eg5 (IC 50 = 140 nM). Induces mitotic arrest in HeLa cells with an IC 50 of 700 nM. Displays antitumor activity.

S-Trityl-L-cysteine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 256)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ACE BIOSCIENCES +91-9395105396 +91-9395105396 Telangana, India 81 58 Inquiry
CHEMSWORTH +91-261-2397244 New Delhi, India 6707 30 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Shanghai Daken Advanced Materials Co.,Ltd +86-371-66670886 China 16209 58 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21675 55 Inquiry
S-TRITYL-L-CYSTEINE TRITYL-L-CYSTEINE S-TRITYL-L-CYSTEINE CRYSTALLINE (+)-S-TRITYL-L-CYSTEINE 97% L-Cysteine, -3,3-D2-S-Trityl (R)-2-Amino-3-(tritylthio)propionic acid (R)-S-Tritylcysteine S-Trityl-(R)-cycteine S-TRITYL-L-CYSTEINE extrapure (2R)-2-AMino-3-[(triphenylMethyl)thio]propanoic Acid S-Trityl-(R)-cysteine Tritylthioalanine S-Trityl-L-cysteine,97% (R)-2-AMino-3-tritylsulfanyl-propionic acid L-CYSTEINE, S-TRITYL 3-(tritylthio)-l-alanin 3-tritylthio-l-alanine s-(triphenylmethyl)-l-cystein L-Cys(Trt)-OH S-Trityl-L-cysteine≥ 98% (HPLC) CYSTEINE(TRT)-OH EG5 INHIBITOR II NSC 83265 S-(TRIPHENYLMETHYL)-L-CYSTEINE (+)-S-TRITYL-L-CYSTEINE L-Cysteine, S-(triphenylmethyl)- S-Trityl-L-cysteine USP/EP/BP H-Cys(Trt)-OH (Cys of Non Animal Origin) (2R)-2-ammonio-3-[(triphenylmethyl)thio]propanoate (2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid Dimethyl 5-bromopyridine-2,3-dicarboxylate H-L-Cys(Trt)-OH S-Tritylcysteine H-CYS(TRT)-OH H-Cys(Trt)-OH (Cys of Animal Origin) S-Tritylcysteine,Kinesin,StritylLCysteine,Apoptosis,328542,inhibit,cell cycle arrest,Inhibitor,NSC 83265,antitumor activities,NSC-83265,ATPase activity,kinesin Eg5,NSC83265,S trityl L Cysteine Tritylthioalanine (H-Cys(Trt)-OH) Impurity IIa-2 (S-triphenylmethylL-cysteine) 2799-07-7 2799-7-7 279-07-7 2799-07-07 7/7/2799 2799/7/7 328542 C6H53CSCD2CHNH2COOH C6H53CSCH2CHNH2CO2H Specialty Synthesis Peptide Synthesis Cysteine/Cystine CARBOXYLIC ACID Amino Acid Derivatives Cell Cycle Regulation Amino Acid Derivatives Amino Acids & Derivatives Aromatics Chiral Reagents Enzyme substrates