Picotamide
- CAS No.
- 32828-81-2
- Chemical Name:
- Picotamide
- Synonyms
- g137;PICOTAMIDE;N,N’-Bis(3-Pyridinylmethyl)-4-Me;n,n’-bis(3-picolyl)-4-methoxyisophthalamide;4-methoxy-n,n’-bis(3-pyridylmethyl)isophthalamide;4-methoxy-n,n’-bis(3-pyridylmethyl)-isophthalamid;4-methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamide;Isophthalamide, 4-methoxy-N,N'-bis(3-pyridylmethyl)-;n,n’-bis(3-pyridinylmethyl)-4-methoxy-3-benzenedicarboxamide;4-METHOXY-N,N'-BIS(3-PYRIDINYLMETHYL)-1,3-BENZENEDICARBOXAMIDE
- CBNumber:
- CB7167904
- Molecular Formula:
- C21H20N4O3
- Molecular Weight:
- 376.41
- MOL File:
- 32828-81-2.mol
- Modify Date:
- 2023/9/4 15:51:00
| Melting point | 128-131℃ |
|---|---|
| Boiling point | 668.1±55.0 °C(Predicted) |
| Density | 1.246±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 5 mg/ml with warming). |
| pka | 13.31±0.46(Predicted) |
| form | White solid. |
| color | White |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month. |
SAFETY
Risk and Safety Statements
| Hazard statements | H303 |
|---|---|
| Precautionary statements | P270-P301+P312-P403-P501c |
| WGK Germany | 2 |
| RTECS | CZ2235500 |
| Toxicity | LD50 i.p. in male mice: 1205 mg/kg (Orzalesi, Selleri, 1976) |
Picotamide Chemical Properties,Uses,Production
Description
Picotamide is an unique antithrombotic agent which acts by selectively inhibiting thromboxane synthesis and blocking platelet thromboxane receptors without affecting prostaglandin synthesis. It is reported to be useful in the treatment of myocardial infarction, cerebrovascular disorders, pulmonary embolism and atherosclerosis.
Uses
Picotamide is a dual inhibitor of thromboxane A2 and thromboxane A2 synthase. It is used in aptamers for targeting coagulation factor XIII and there used for treatment of thrombosis.
Picotamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 52)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Hetero Drugs Limited | +91-4023704923 +91-4023704923 | Telangana, India | 296 | 58 | Inquiry |
| Medilink Pharmachem | +91 (79) 3007-0133 | New Delhi, India | 424 | 50 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| LEAPCHEM CO., LTD. | +86-852-30606658 | China | 43348 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| Olix (Shanghai) Pharmaceutical Technology Co., Ltd | 17316404525 | China | 9626 | 58 | Inquiry |
| Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd. | 025-66061636 18013972705 | China | 5067 | 58 | Inquiry |
| Nanjing Tengyi Biotechnology Co., Ltd | 025-58851786 17714337195 | China | 5595 | 58 | Inquiry |
| Suzhou Zhixin Biotechnology Co., Ltd. | 0512-65118909 15162312715 | China | 2992 | 58 | Inquiry |
32828-81-2(Picotamide)Related Search:
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3-[(Aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-Thiophenecarboxamide
3-METHYL-4-METHOXYBENZYLAMINE
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4-METHOXY-N,N'-BIS(3-PYRIDINYLMETHYL)-1,3-BENZENEDICARBOXAMIDE
PICOTAMIDE
4-methoxy-n,n’-bis(3-pyridylmethyl)-isophthalamid
4-methoxy-n,n’-bis(3-pyridylmethyl)isophthalamide
g137
n,n’-bis(3-picolyl)-4-methoxyisophthalamide
n,n’-bis(3-pyridinylmethyl)-4-methoxy-1,3-benzenedicarboxamide
n,n’-bis(3-pyridinylmethyl)-4-methoxy-3-benzenedicarboxamide
4-methoxy-N,N'-bis(3-pyridylmethyl)isophthaldiamide
-1,3-Benzenedicarboxamide, N,N'-bis(3-pyridinylmethyl)-4-methoxy
Isophthalamide, 4-methoxy-N,N'-bis(3-pyridylmethyl)-
N,N’-Bis(3-Pyridinylmethyl)-4-Me
4-methoxy-1-N,3-N-bis(pyridin-3-ylmethyl)benzene-1,3-dicarboxamide
1,3-Benzenedicarboxamide, 4-methoxy-N1,N3-bis(3-pyridinylmethyl)-
inhibit,Picotamide,Inhibitor,Prostaglandin Receptor,Antiplatelet,Microalbuminuria,Carotid plaques
32828-81-2
C21H20N4O3H2O
C21H20N4O3
Enzymes, Inhibitors, and Substrates
Enzyme Inhibitors
Enzyme Inhibitors by Enzyme
Thromboxane synthase
R to Z
BioChemical
Biochemicals and Reagents