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Polyquaternium-10

Polyquaternium-10 Structure
CAS No.
81859-24-7
Chemical Name:
Polyquaternium-10
Synonyms
QUATERNIUM-19;(55353-19-0;Polyquaternium-10;cellulose 2-hydroxyethyl 2;FPDHGZVZKKPIDU-UHFFFAOYSA-L;Polyquaternium-10CAS:81859-24-7;Polyquaternium-10 (quaternium-19);Polyquaternium-10 (1000 MPA.S at 2%);Polyquaternium-10 Cas NO.: 81859-24-7;cationic hydroxyethylcellulose, chloride
CBNumber:
CB7207899
Molecular Formula:
C8H6O6
Molecular Weight:
198.12964
MOL File:
81859-24-7.mol
Modify Date:
2024/5/10 14:01:29

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS09
Hazard statements  H411
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
Toxicity LD50 oral in rat: > 2gm/kg

Polyquaternium-10 Chemical Properties,Uses,Production

Description

Polyquaternium 10 is a range of polymeric quaternary ammonium salts of hydroxyethyl cellulose (HEC) reacted with trimethyl ammonium substituted epoxide. Polyquaternium 10 solutions are non-Newtonian and are commercially available 1) in several viscosity grades depending on their molecular weights (they contribute to viscosity of formulations), and 2) with“high” to “moderate”cationic substitution. In vivo tests showed that these cationic cellulosic polymers protect the skin from aggression by anionic surfactants.

Chemical Properties

Polyquaternium 10 is a water soluble, white granulated powder that is a widely used ingredient in hair care products because of its anti-static and moisturizing properties. It is also considered a film former, supplying a sheen and coating to hair strands by easily being absorbed by proteins.

Uses

polyquaternium-10 is a cellulose polymer and conditioning agent used in skin-conditioning formulations.
There are numerous cationic polymers that provide conditioning benefits, especially improved wet combing and reduced static charge. Important examples of these polymers are Polyquaternium-10, a quaternized hydroxyethylcellulose polymer; Polyquaternium-7, a Hair Conditioners 339 copolymer of diallyldimethylammonium chloride and acrylamide; Polyquaternium-11, a copolymer of vinylpyrrolidone and dimethylaminoethyl methacrylate quaternized with dimethyl sulfate; Polyquaternium-16, a copolymer of vinylpyrrolidone and quaternized vinylimidazole; and Polyquaternium-6, a homopolymer of diallyldimethylammonium chloride.

Chemical Reactivity

Polyquaternium-10 is a cationic, surface-active polymer that is adsorbed by keratinous surfaces, such as hair and skin (stratum corneum). The adsorption of the polymer was not readily affected by pH in the range of 4 to 10. It undergoes slow hydrolytic cleavage outside this pH range. Sorption of Polyquaternium-10 to keratinous surfaces was decreased by the addition of electrolytes (salts), such as aluminum, iron, calcium, or sodium. Polyquaternium-10 is biologically degradable. The presence of ethyl alcohol or propylene glycol adds to the stability of PoIyquaternium-10. 

Side effects

Polyquaternium-10 is generally considered to be safe for topical use. It is mild, non-irritant and non-sensitizing to the skin, hence used in a wide range of cosmetic products. At 2% concentration in the skincare and haircare formulation, it is non-irritant and does not show any signs of allergic reaction on your skin. Hence Polyquaternium-10 is considered to be safe for use in cosmetics at 2% concentration. At 5% concentration, it is known to show mild irritation to your skin and eyes. Polyquaternium-10 is considered to be entirely safe for use at 2% concentration or below. Anything above it can cause slight irritation to your skin and eyes.

Safety

polyquaternium-10 is safe as a cosmetic ingredient in its current concentrations and uses. In 2005, the Expert Panel evaluated new data and confirmed the above conclusion. Polyquaternium 10 has low toxicity. Skin studies indicated that it was poorly absorbed into the skin. This is due to the fact that it binds to the protein, keratin, in the skin and hair. In high concentrations, 5% or greater, polyquarternium 10 can be mildly irritating to the skin and eyes. However, when used at 2% or lower this effect is not observed. It also is not genotoxic or photosensitizing.

Polyquaternium-10 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 161)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Oryn Healthcare LLP +91-9725003311 +91-9725003311 Gujarat, India 15 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Bodar Industries 08048611019 Gujarat, India 42 58 Inquiry
SG Green Tech Health & Beauty 08048604544 Uttar Pradesh, India 6 58 Inquiry
Winways Chemtech 08048962053 Mumbai, India 6 58 Inquiry
Sakshi Corporation 07942539673 Mumbai, India 223 58 Inquiry
Sona Enterprise 08046045631 Ahmedabad, India 20 58 Inquiry
M/S Abheda Chemlab 08047313604 Delhi, India 2 58 Inquiry
Kosmetika Enterprises 08047639652 Delhi, India 10 58 Inquiry
BLiT (Hefei)Chemical Co.,Ltd +86-551-62622640 China 293 58 Inquiry

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