Hh-Ag 1.3

Hh-Ag 1.3 Structure
CAS No.
364590-63-6
Chemical Name:
Hh-Ag 1.3
Synonyms
Hh-Ag 1.3;Smoothened Agonist, HCl;Frizzled6 agonist SAG1.3;SAG . dihydrochloride (water soluble);3-Chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide;Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-;3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide,hydrate,dihydrochloride
CBNumber:
CB72524538
Molecular Formula:
C28H28ClN3OS
Molecular Weight:
490.06
MOL File:
364590-63-6.mol
Modify Date:
2023/4/23 13:52:06

Hh-Ag 1.3 Properties

Boiling point 688.6±55.0 °C(Predicted)
Density 1.30±0.1 g/cm3(Predicted)
pka 10?+-.0.40(Predicted)
form White to off-white solid.
Water Solubility Soluble in water.
Sensitive Light Sensitive & Hygroscopic

Hh-Ag 1.3 price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 566660 Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem A cell-permeable Smoothened Agonist, SAG, CAS 364590-63-6, modulates the coupling of Smo with its downstream effector by interacting with the Smo hept 364590-63-6 1MG ₹21460 2022-06-14 Buy
Product number Packaging Price Buy
566660 1MG ₹21460 Buy

Hh-Ag 1.3 Chemical Properties,Uses,Production

Uses

Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.

Hh-Ag 1.3 Preparation Products And Raw materials

Raw materials

Preparation Products

Hh-Ag 1.3 Suppliers

Global( 11)Suppliers
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Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Nantong Hanfang Biotechnology Co. , Ltd. 18616537568 China 30968 58 Inquiry
Alfa Chemistry +1 (201) 478-8534 United States 6824 0 Inquiry
Glentham Life Sciences +44 (2033) 978-798 United Kingdom 1429 0 Inquiry
CMS Chemicals Limited +44 1235 831160 United Kingdom 3714 60 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6256 80 Inquiry
Aikon International Limited 025-58851090 13611564524 China 15952 58 Inquiry
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 China 18021 56 Inquiry
3-Chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide Smoothened Agonist, HCl SAG . dihydrochloride (water soluble) Hh-Ag 1.3 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide,hydrate,dihydrochloride Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]- Frizzled6 agonist SAG1.3 364590-63-6