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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Stem Cells & Wnt >Hedgehog / Smoothened antagonist >NVP-LDE225

NVP-LDE225

NVP-LDE225 Structure
CAS No.
956697-53-3
Chemical Name:
NVP-LDE225
Synonyms
Sonidegib;Erismodegib;LDE225;CS-65;AZP-577;NVP-LDE225;Sonidegib HCL;SONIDEGIB(LDE225);LDE225 (NVP-LDE225);LDE-225 (SONIDEGIB)
CBNumber:
CB52515129
Molecular Formula:
C26H26F3N3O3
Molecular Weight:
485.5
MOL File:
956697-53-3.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

NVP-LDE225 Properties

Melting point 154-157°C
Boiling point 544.5±50.0 °C(Predicted)
Density 1.255
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form White solid.
pka 9.53±0.70(Predicted)
color Light Purple

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P271-P280-P261
HS Code  2934999090

NVP-LDE225 Chemical Properties,Uses,Production

Definition

ChEBI: A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as it phosphate salt) for treatment of locally advanced basal cell carcinoma.

NVP-LDE225 Preparation Products And Raw materials

Raw materials

4-Trifluoromethoxyphenylboronic acid 2-Chloro-5-nitropyridine 3-Bromo-4-methylbenzoic acid 2-Amino-5-nitropyridine

Preparation Products

NVP-LDE225 Suppliers

Global( 181)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Henan Tianfu Chemical Co.,Ltd. +86-0371-55170693 +86-19937530512 China 21676 55 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29901 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19553 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49391 58 Inquiry
Supplier Advantage
A.J Chemicals 58
Pharmaffiliates Analytics and Synthetics P. Ltd 58
CLEARSYNTH LABS LTD. 58
Capot Chemical Co.,Ltd. 60
Henan Tianfu Chemical Co.,Ltd. 55
ATK CHEMICAL COMPANY LIMITED 60
career henan chemical co 58
BOC Sciences 58
Chongqing Chemdad Co., Ltd 58
CONIER CHEM AND PHARMA LIMITED 58

NVP-LDE225 Spectrum

NVP-LDE225(956697-53-3)1HNMR

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Erismodegib Diphosphate,LDE225 N-(6-((2S,6R)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)biphenyl-3-carboxamide N-(6-((2R,6S)-2,6-Dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)biphenyl-3-ca LDE225 (NVP-LDE225,ERISMODEGIB);NVP-LDE225 N-(6-((2R,6S)-2,6-dimethylmorpholino)pyridin-3-yl)-2-methyl-4,-(trifluoromethoxy)-[1,1,-biphenyl]-3-carboxamide LDE225 (NVP-LDE225) [1,1'-Biphenyl]-3-carboxaMide, N-[6-[(2R,6S)-2,6-diMethyl-4-Morpholinyl]-3-pyridinyl]-2-Methyl-4'-(trifluoroMethoxy)-, rel- NVP-LDE225(LDE225,ErisModegib) LDE225 (NVP-LDE225,ErisModegib) NVP-LDE225/erisModegib ERISMODEGIB,NVP-LDE225 rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide LDE225 (NVP-LDE225,Erismodegib) AZP-577 NVP-LDE225 rel-N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide Sonidegib (NVP-LDE225) NVP-LDE225,Sonidegib Sonidegib (LDE-225,NVP-LDE225) Erismodegib (LDE225) Sonidegib (Erismodegib, NVP-LDE225) SONIDEGIB(LDE225) NVP-LDE225 USP/EP/BP Sonidegib /Erismodegib Sonidegib-d4 (morphonyl D4)Q: What is Sonidegib-d4 (morphonyl D4) Q: What is the CAS Number of Sonidegib-d4 (morphonyl D4) Q: What is the storage condition of Sonidegib-d4 (morphonyl D4) LDE225 (NVP-LDE225,Sonidegib) N-[6-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-3-pyridinyl]-2-yl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide Sonidegib HCL CS-65 Erismodegib LDE225 Sonidegib N-(6-(cis-2,6-Dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide Sonidegib Erismodegib LDE225 LDE-225 LDE-225 (SONIDEGIB) N-(6-(cis-2,6-Dimethylmorpholino)pyridin-3-yl)-2-methyl-4'-(trifluoromethoxy)-[1,1'-biphenyl]-3-carboxamide 956697-53-3 C26H26F3N3O3 Aromatics Chiral Reagents Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals