D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI)

D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) Structure
CAS No.
866607-35-4
Chemical Name:
D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI)
Synonyms
Canagliflozin-2;Canagliflozin Tetra;D-glucitol tetraacetate;Cagliflozin Impurity 12;Canagliflozin Impurity 88;canagliflozin impurities8;Tetra Acetyl Canagliflozin;canagliflozin impurities621;(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(3-((5-(4-fluorophenyl)...;(2R,3R,4R,5S,6S)-2-(acetoxyMethyl)-6-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)tet
CBNumber:
CB72668294
Molecular Formula:
C32H33FO9S
Molecular Weight:
612.66
MOL File:
866607-35-4.mol
MSDS File:
SDS
Modify Date:
2024/1/2 18:26:26

D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) Properties

Melting point 160-170 °C
Boiling point 658.3±55.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
vapor pressure 0Pa at 20℃
solubility soluble in Chloroform, Ethyl Acetate, Methanol
form Solid
color White
LogP 5.5 at 20℃

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) Chemical Properties,Uses,Production

Uses

The title compound is an intermediate in the synthesis of Canagliflozin which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.

D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 134)Suppliers
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Synthetic Research Pharma Laboratories Pvt Ltd +91 9848023377 Hyderabad, India 116 58 Inquiry
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D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S)- (9CI) (2R,3R,4R,5S,6S)-2-(acetoxyMethyl)-6-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol tetraacetate Tetra Acetyl Canagliflozin D-Glucitol,1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]Methyl]-4-Methylphenyl]-, tetraacetate, (1S) (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol 2,3,4,6-Tetraacetate Canagliflozin impurity 3/Tetra Acetyl Canagliflozin/(2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(3-((5-(4-fluorophenyl) thiophen-2-yl)methyl)-4-methylphenyl)tetrahydro-2H-pyran- 3,4,5-triyl triacetate Canagliflozin Tetra Cagliflozin Impurity 12 Canagliflozin-2 D-glucitol tetraacetate [(2R,3R,4R,5S,6S)-3,4,5-Triacetyloxy-6-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]oxan-2-yl]methyl acetate (3(R),4(R),5(S)-triacetoxy-6(S)-{3-[5-(4-fluoro-phenyl)-thiophen-2-ylmethyl]-4-methyl-phenyl}-tetrahydro-pyran-2(R)-yl)methanol acetate (1 S)-1,5-dehydro-1- C-[3-[[5-(4- fluorophenyl)-2-thiophene] methyl ]-4-methylphenyl ]- D- glucol tetraacetate D-Glucitol, 1,5-anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-, 2,3,4,6-tetraacetate, (1S)- (2R,3R,4R,5S,6S)-2-(acetoxyMethyl)-6-(3-((5-(4-fluorophenyl)thiophen-2-yl)Methyl)-4-Methylphenyl)tet Canagliflozin Impurity 88 (2R,3R,4R,5S,6S)-2-(acetoxymethyl)-6-(3-((5-(4-fluorophenyl)... canagliflozin impurities621 canagliflozin impurities8 Tetra Acetyl CanagliflozinQ: What is Tetra Acetyl Canagliflozin Q: What is the CAS Number of Tetra Acetyl Canagliflozin Q: What is the storage condition of Tetra Acetyl Canagliflozin Q: What are the applications of Tetra Acetyl Canagliflozin (2R,3R,4R,5S.6S)-2-(acetyl oxygenPolymethyl)-6-(3-1(5-(4-fluorobenzene)Base)thiophene-2-yl)methyl)-4-methylPHENYL) Tetrahydrogen-2H-pyran-3,4,5-Trikyd triacetate (2R,3R,4R,5S,6S)-2-(AcetyloxygenSubmethyl)-6-(3-((5-(4-FluorobenzeneBase) Thiophene-2-base)Methyl)-4-MethylPhenyl) Tetrahydrogen-2H-Pyran-3,4,5-Trikyd triacetate (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluoropheny1)-2- thienyl]methyl]-4-methylpheny1]-D-glucitol tetraacetate 866607-35-4 C32H33FO9S