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2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene

2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Structure
CAS No.
898566-17-1
Chemical Name:
2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene
Synonyms
2-(4-Fluorophenyl)-5-(5-iodo-2-Methylbenzyl)thiophene;2-(4-Fluorophenyl);Canagliflozin INT5;)-5-(5-iodo-2-methyL;Canagliflozin iMpurity D;-5-(5-iodo-2-methylbenzyl);Canagliflozin Intermediate1;2-(4-Fluorophenyl)-5-(5- iodo-methylphenyI) metl;2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl];2-(4-Fluorophenyl)-5-(5-iodo-methylphenyl) methyl] thiophene
CBNumber:
CB61463466
Molecular Formula:
C18H14FIS
Molecular Weight:
408.27
MOL File:
898566-17-1.mol
MSDS File:
SDS
Modify Date:
2025/3/3 9:06:10

2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Properties

Melting point 109-110 °C
Boiling point 450.2±45.0 °C(Predicted)
Density 1.533
vapor pressure 0-0Pa at 20-25℃
storage temp. 2-8°C(protect from light)
solubility DMSO (Sparingly), Methanol (Slightly)
form Solid
color Pale Yellow
LogP 7.5 at pH7

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Chemical Properties,Uses,Production

Chemical Properties

Pale Yellow Solid.

Uses

2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene is an antidiabetic agent and a Canagliflozin (C175190) intermediate. Canagliflozin is a sodium/glucose cotransporter 2 (SGLT2) inhibitor and a candidate for the treatment of type 2 diabetes and obesity.

2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Preparation Products And Raw materials

Raw materials

Preparation Products

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Thiophene, 2-(4-fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]- 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene Canagliflozin iMpurity D 2-((5-IODO-2-METHYLPHENYL)METHYL)-5-(4-FLUOROPHENYL)THIOPHENE Canagliflozin INT5 Canagliflozin Intermediate1 -5-(5-iodo-2-methylbenzyl) Canagliflozin impurity DQ: What is Canagliflozin impurity D Q: What is the CAS Number of Canagliflozin impurity D Q: What is the storage condition of Canagliflozin impurity D 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophen... 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene cas 898566-17-1 Canagliflozin intermediates,2-(4-Fluorophenyl)-5-[(5-iodo-2- methylphenyl)methyl]thiophene 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene ISO 9001:2015 REACH 2-(4-FLUOROPHENYL)-5-[(5-IODO-2-METHYLPHENYL)METHYL]THIOPHENE 898566-17-1 )-5-(5-iodo-2-methyL 2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl] 2-(4-Flurophenyl)-5-[(5-Iodo-2-methylphenyl] methyl] Thiophene 2-(4-Fluorophenyl)-5-(5-iodo-2-Methylbenzyl)thiophene 2-(4-Fluorophenyl) 2-(4-Fluorophenyl)-5-(5-iodo-methylphenyl) methyl] thiophene 2-(4-Fluorophenyl)-5-(5- iodo-methylphenyI) metl 2-(4-Fluoropheny1)-5-[(5-iodo-2 methylphenyl)methyl]thiophene Canagliflozin impurity-(2-(4-Fluorophenyl)-5-[(5-iodo-2-methylphenyl)methyl]thiophene) 898566-17-1 C18H14FIS C18H14FI 898566-17-1