Chapso
- CAS No.
- 82473-24-3
- Chemical Name:
- Chapso
- Synonyms
- CHAPSO;Hydroxy analog;CHAPSO extrapure;CHAPSO detergent;CHAPSO SIGMAULTRA;CHAPSO,ELECTROPHORESISGRADE;CHAPSO Buffer extrapure, 99%;CHAPSO ELECTROPHORESIS REAGENT;CHAPSO - CAS 82473-24-3 - Calbiochem;CHAPSO Vetec(TM) reagent grade, >=98%
- CBNumber:
- CB7323821
- Molecular Formula:
- C32H58N2O8S
- Molecular Weight:
- 630.88
- MOL File:
- 82473-24-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/5 17:10:12
| Melting point | 184-186 °C(lit.) |
|---|---|
| Density | 1.0453 (rough estimate) |
| refractive index | 1.6900 (estimate) |
| storage temp. | -20°C |
| solubility | H2O: 10 mg/mL at 20 °C, clear, colorless |
| form | White solid |
| color | White crystalline |
| Odor | Odorless |
| Water Solubility | 10 g/l at 20 °C |
| Merck | 13,2052 |
| BRN | 5842642 |
| CAS DataBase Reference | 82473-24-3(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| F | 3-10 |
| HS Code | 2924297099 |
Chapso price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C4695 | CHAPSO BioXtra | 82473-24-3 | 500MG | ₹11073.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C4695 | CHAPSO BioXtra | 82473-24-3 | 1G | ₹16443.18 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C3649 | CHAPSO ≥98% | 82473-24-3 | 500MG | ₹6538.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C4695 | CHAPSO BioXtra | 82473-24-3 | 5G | ₹59299.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C3649 | CHAPSO ≥98% | 82473-24-3 | 1G | ₹9439.4 | 2022-06-14 | Buy |
Chapso Chemical Properties,Uses,Production
Chemical Properties
Chapso is a white crystalline powder. It is a zwitterionic detergent similar to Chaps, however, Chapso is more soluble and particularly better for the solubilization of integral membrane proteins.
Uses
Chapso is a nondenaturing biological detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.
Application
3-(cholamidopropyl)(dimethylammonio)-2-hydroxy-1-propanesulfonate (CHAPSO) may be used in bicelle preparation for β2-adrenergic receptor reconstitution.
CHAPSO has been used:
in a study to assess the processes of liposome solubilization and reconstitution of two transport proteins
in a study to investigate a novel bicelle system for orienting macromolecules over a wide temperature range
as a mixture with dilauroyl phosphatidylcholine (DLPC) in solid-state nuclear magnetic resonance (NMR) technique to study membrane-associated proteins
A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.
General Description
CHAPSO is a non-denaturing zwitterionic bile salt derivative, derived from Chaps by the addition of a functional hydroxyl group.
Purification Methods
Dissolve this zwitterionic detergent (~ 60g) in 40% aqueous MeOH and stir it with the mixed-bed ion-exchange resin RG-501 x 8 (100g, Bio-Rad) until the pH of the supernatant is ~ 7. Filter off the resin and evaporate the filtrate to dryness under reduced pressure. Check for homogeneity by TLC on silica gel G in 95% MeOH/5% NH4OH and visualize the spot with iodine vapour (see CHAPS above). [Hjelmeland et al. Anal Biochem 130 72 1983, Matuo et al. Methods Enzymol 198 155 1991.]
Chapso Preparation Products And Raw materials
Raw materials
Preparation Products
Chapso Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| LOBA CHEMIE PVT.LTD. | 91-22-6663 6699 | Mumbai, India | 3077 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Maas Pharma Chemicals | +91-9958666224 | Delhi, India | 1607 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 6011 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| CHEMSWORTH | 30 |
| Otto Chemie Pvt. Ltd. | 58 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
| LOBA CHEMIE PVT.LTD. | 58 |
| Central Drug House(P) Ltd. | 58 |
| Triveni chemicals | 58 |
| CLEARSYNTH LABS LTD. | 58 |
| A.J Chemicals | 58 |
| Maas Pharma Chemicals | 58 |
| Hebei Yanxi Chemical Co., Ltd. | 58 |
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