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Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate

CAS No.: 174072-89-0

Chemical Name:: Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate

Synonyms: RELU-001;Relugolix Intermediate 6;2-Amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylic a;ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOX...;Ethyl 2-amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylat;2-Amino-4-methyl-5-(4-nitrobenzene Ethyl thiophene-3-carboxylate;ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOXYLATE;2-Amino-4-methyl-5- (4-nitrophenyl) -3-thiophene carboxylate ethyl ester;2-amino-4-methyl-5-(4-nitrophenyl)-thiophen-3-carboxylic acid ethyl ester;2-Amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylic acid ethyl ester

CBNumber:: CB7325744

Molecular Formula:: C14H14N2O4S

Molecular Weight:: 306.34

MOL File:: 174072-89-0.mol

MSDS File:: SDS

Modify Date:: 2024/4/9 22:15:29

Request For Quotation

Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate Properties

Boiling point	464.6±45.0 °C(Predicted)
Density	1.337
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
pka	-0.68±0.10(Predicted)
InChI	InChI=1S/C14H14N2O4S/c1-3-20-14(17)11-8(2)12(21-13(11)15)9-4-6-10(7-5-9)16(18)19/h4-7H,3,15H2,1-2H3
InChIKey	CXRJNUVDWUINBY-UHFFFAOYSA-N
SMILES	C1(N)SC(C2=CC=C([N+]([O-])=O)C=C2)=C(C)C=1C(OCC)=O

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS08
Signal word	Warning
Hazard statements	H302-H319-H351-H315-H335
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P201-P202-P281-P308+P313-P405-P501

Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate Chemical Properties,Uses,Production

Uses

Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate is an intermediate compound used in the synthesis of Relugolix, which belongs to a class of gonadotropin-releasing hormone (GnRH) receptor antagonists used to treat advanced prostate cancer in adult men. Relugolix belongs to a group of Gonadotropin-releasing hormone (GnRH) receptor antagonists that are used to treat advanced prostate cancer in adult men.

Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate Preparation Products And Raw materials

Raw materials

1-(4-NITROPHENYL)PROPAN-1-ONE 4-NITROPHENYLACETONE 4-Nitrophenylacetic acid Diethylamine Ethyl cyanoacetate

1-Bromo-4-nitrobenzene

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Preparation Products

ethyl 2-((ethoxycarbonyl)amino)-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate

Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)thiophene-3-carboxylate Suppliers

Global( 125)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
VGS SYNTHESIS PRIVATE LIMITED	+91-9866975588 +91-9866975588	Hyderabad, India	1818	58	Inquiry
Radison Labs Private Limited	+91-7337551966 +91-7337551966	Hyderabad, India	58	58	Inquiry
ZunaChem Pvt Ltd	+91-7337409191 +91-7093354085	Hyderabad, India	43	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Jinan Carbotang Biotech Co.,Ltd.	+8615866703830	China	7287	58	Inquiry
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	China	20327	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29900	58	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry

Supplier	Advantage
VGS SYNTHESIS PRIVATE LIMITED	58
Radison Labs Private Limited	58
ZunaChem Pvt Ltd	58
CLEARSYNTH LABS LTD.	58
Jinan Carbotang Biotech Co.,Ltd.	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
CONIER CHEM AND PHARMA LIMITED	58

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ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOXYLATE 2-Amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylic acid ethyl ester 2-Amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylic acid ethyl ester Ethyl 2-amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylat RELU-001 2-Amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylic a 3-Thiophenecarboxylic acid, 2-amino-4-methyl-5-(4-nitrophenyl)-, ethyl ester 2-amino-4-methyl-5-(4-nitrophenyl)-thiophen-3-carboxylic acid ethyl ester ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOXYLATE ISO 9001：2015 REACH ETHYL 2-AMINO-4-METHYL-5-(4-NITRO-PHENYL)-THIOPHENE-3-CARBOX... Ethyl-2-Amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylateQ: What is Ethyl-2-Amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylate Q: What is the CAS Number of Ethyl-2-Amino-4-methyl-5-(4-nitro-phenyl)-thiophene-3-carboxylate Relugolix Intermediate 6 2-Amino-4-methyl-5-(4-nitrobenzene Ethyl thiophene-3-carboxylate 2-Amino-4-methyl-5- (4-nitro-phenyl)-thiophene-3- carboxylic acid ethyl estei Ethyl 2-amino-4-methyl-5-(4-nitrophenyl)-3-thiophenecarboxylate (API Intermediate) 2-Amino-4-methyl-5- (4-nitrophenyl) -3-thiophene carboxylate ethyl ester 174072-89-0