Flavopiridol
- CAS No.
- 146426-40-6
- Chemical Name:
- Flavopiridol
- Synonyms
- Alvocidib;CS-180;C077990;L86-8275;L-868275;L 868275;Hmr 1275;FLAVOPIRIDOL;Flavopirodol;HMR-1275; L86-8275
- CBNumber:
- CB7362013
- Molecular Formula:
- C21H20ClNO5
- Molecular Weight:
- 401.84
- MOL File:
- 146426-40-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:16
| Melting point | 52.5 °C |
|---|---|
| Boiling point | 603.6±55.0 °C(Predicted) |
| Density | 1.448±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | insoluble in H2O; ≥40.2 mg/mL in DMSO; ≥85.4 mg/mL in EtOH with gentle warming and ultrasonic |
| form | Yellow powder. |
| pka | 6.16±0.40(Predicted) |
| color | Light yellow to yellow |
| InChIKey | BIIVYFLTOXDAOV-YVEFUNNKSA-N |
| SMILES | C1(C2=CC=CC=C2Cl)OC2=C([C@H]3CCN(C)C[C@H]3O)C(O)=CC(O)=C2C(=O)C=1 |
| CAS DataBase Reference | 146426-40-6(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| HS Code | 2934999090 | |||||||||
| NFPA 704 |
|
Flavopiridol Chemical Properties,Uses,Production
Uses
Antineoplastic (cyclin-dependent kinase inhibitor)[Note—The trivial name, flavopiridol, has appeared in literature].
Anticancer Research
It is a synthetic derivative of rohitukine plant alkaloid which is obtained fromDysoxylum binectariferum, which is active against leukemia, lymphomas and solidtumors (Shoeb 2006).
Flavopiridol Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 216)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | China | 892 | 58 | Inquiry |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | China | 29798 | 60 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | China | 15395 | 58 | Inquiry |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | China | 52861 | 58 | Inquiry |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
146426-40-6(Flavopiridol)Related Search:
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FLAVOPIRIDOL
2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3s,4r)-3-hydroxy-1-methyl-4-piperidyl]chromen-4-one
4H-1-Benzopyran-4-one, 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-
(-)cis-5,7-Dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one
C077990
Hmr 1275
L 868275
L-868275
L86-8275
Flavopirodol
Flavopiridol(Alvocidib)
vopiridol(Alvocidib)
2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-Methylpiperidin-4-yl]-4H-chroMen-4-one
FLAVOPIRIDOL; HMR-1275;L868275
Alvocidib, Free Base
Flavopiridol
2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidyl]chromen-4-one
Alvocidib(Flavopiridd)
Flavopiridol, >=99%
CS-180
Flavopiridol
(HMR-1275, Alvocidib, L868275)
HMR-1275; L86-8275
FLAVOPIRIDOL (ALVOCIDIB; L868275; HMR-1275)
Alvocidib
Donepezil Impurity 63
L868275|||Alvocidib|||NSC 649890 HCl|||HMR-1275
146426-40-6
C21H20ClNO5
API intermediates
APIS