Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >Biochemical Engineering >Chinese Herbs >PICROTOXININ

PICROTOXININ

PICROTOXININ Structure
CAS No.
17617-45-7
Chemical Name:
PICROTOXININ
Synonyms
PICROTOXININ;Picrotoxinin-RM;Picrotoxinin CRS;PICROTOXININ USP/EP/BP;Yellowmouth Dutchmanspipe Root;6a-beta,8as*,8b-beta,9r*))-6-beta;ahydro-2a-hydroxy-8b-methyl-9-(1-methylethenyl)-,(1ar-(1a-alpha,2a-beta,3-bet;3,6-Methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-8b-methyl-9-(1-methylethenyl)-, (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)-
CBNumber:
CB7420980
Molecular Formula:
C15H16O6
Molecular Weight:
292.28
MOL File:
17617-45-7.mol
MSDS File:
SDS
Modify Date:
2024/12/18 14:15:30
Request For Quotation

PICROTOXININ Properties

Melting point 203-205°C
alpha D17 +4.4° (c = 4.28 in abs alc), +3.49° (c = 7.57 in acetone)
Boiling point 354.22°C (rough estimate)
Density 1.2207 (rough estimate)
refractive index 1.4359 (estimate)
storage temp. 2-8°C
pka 13.18±0.60(Predicted)
form Solid
color White to off-white
LogP -0.130 (est)
EPA Substance Registry System Picrotoxinin (17617-45-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H300
Precautionary statements  P301+P310+P330
Hazard Codes  T+
Risk Statements  25-28
Safety Statements  13-20-45-36/37-28
RIDADR  3172
WGK Germany  3
RTECS  PC5150000
HazardClass  6.1(a)
PackingGroup  I
Toxicity LD50 i.p. in mice: 3 mg/kg (Jarboe)

PICROTOXININ price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P8390 Picrotoxinin 17617-45-7 250MG ₹21346.9 2022-06-14 Buy
Product number Packaging Price Buy
P8390 250MG ₹21346.9 Buy

PICROTOXININ Chemical Properties,Uses,Production

Biochem/physiol Actions

GABAA receptor antagonist; binds to the GABA receptor-linked Cl? channel.

Enzyme inhibitor

These neurotoxic GABAA receptor antagonists, consisting of a nearly 1:1 mixture of picrotoxinin, (FW = 292.29 g/mol; CAS 17617-45-7) and picrotin (FW = 310.30 g/mol; CAS 124-87-8), is a bitter-tasting (hence the Greek prefix picros) principle, also known as cocculin, from fishberry seeds (Anamirta cocculus) and the Philippine bayating (Tinomiscium philippinense). Picrotoxin binds to the chloride channel of the receptor without displacing g-aminobutyric acid. Picrotoxin is highly toxic, exerting both stimulant and convulsant effects, and care must be exercised when handling this agent.

PICROTOXININ Preparation Products And Raw materials

Raw materials

Preparation Products

PICROTOXININ Suppliers

Global( 72)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32161 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 22787 58 Inquiry
ABCR GmbH & CO. KG 49 721 95061 0 Germany 6831 75 Inquiry
United States Biological 800.520.3011 or 781.639.5092 United States 6214 80 Inquiry
Aikon International Limited 025-58851090 13611564524 China 15951 58 Inquiry
Shanghai Hao Biological Technology Co., Ltd. 021-58116080 18019263206 CHINA 6906 58 Inquiry
Foshan Treasure Biotechnology Co., Ltd 0757-85921206 18520245316 China 12661 58 Inquiry
Shanghai Beiwanta Biotechnology Co., Ltd. 021-67187366 19901745723 China 9355 58 Inquiry
Shanghai Moqi Biological Technology Co., LTD 021-38218169 13341702378 China 9136 58 Inquiry
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 China 6210 58 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Dideu Industries Group Limited 58
ABCR GmbH & CO. KG 75
United States Biological 80
Aikon International Limited 58
Shanghai Hao Biological Technology Co., Ltd. 58
Foshan Treasure Biotechnology Co., Ltd 58
Shanghai Beiwanta Biotechnology Co., Ltd. 58
Shanghai Moqi Biological Technology Co., LTD 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

17617-45-7(PICROTOXININ)Related Search:

Dihydromyrcenol METHYL TUBERATE 2-(2-ISOBUTOXYETHOXY)ETHANOL BUTYL L-LACTATE 1,2-EPOXY-7-OCTENE
Molecular complex (1:1) of picrotin and picrotoxinin,picrotoxinin,compd.withpicrotin(1:1 PICROTOXININ Isopentyl isobutyrate ISOBUTYL LACTATE 4-METHOXYCYCLOHEXANECARBOXYLIC ACID
(S)-5-Hydroxymethyldihydrofuran-2-one Undecenoic acid 1,3-CYCLOPENTANEDIOL (+)-3-METHYLHEXANEDIOIC ACID DIHYDRO-4,4-DIMETHYL-2(3H)-FURANONE
Ethyl 2-hydroxyisobutyrate ETHYL 1-HYDROXYCYCLOPENTANE-CARBOXYLATE (R)-2-HYDROXY-4-METHYLPENTANOIC ACID
chevron_left

1of4

chevron_right
6a-beta,8as*,8b-beta,9r*))-6-beta ahydro-2a-hydroxy-8b-methyl-9-(1-methylethenyl)-,(1ar-(1a-alpha,2a-beta,3-bet PICROTOXININ Yellowmouth Dutchmanspipe Root Picrotoxinin CRS 3,6-Methano-8H-1,5,7-trioxacyclopenta[ij]cycloprop[a]azulene-4,8(3H)-dione, hexahydro-2a-hydroxy-8b-methyl-9-(1-methylethenyl)-, (1aR,2aR,3S,6R,6aS,8aS,8bR,9R)- PICROTOXININ USP/EP/BP Picrotoxinin-RM 17617-45-7 C15H16O6 C15H16O6H2O GABAA receptor antagonist; binds to the GABA receptor-linked Cl- channel. Cell Signaling and Neuroscience Cell Biology BioChemical Ligand-Gated Ion Channels Ion Channels GABA and Glycine Receptor Modulators Miscellaneous Natural Products AntagonistsIon Channels GABA and Glycine Receptor Modulators GABAergics Ligand-Gated Ion Channels Neurotransmitters