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Ethyl 2-hydroxyisobutyrate

Ethyl 2-hydroxyisobutyrate Structure
CAS No.
80-55-7
Chemical Name:
Ethyl 2-hydroxyisobutyrate
Synonyms
Ethyl α-hydroxyisobu;ETHYL 2-METHYLLACTATE;Ethyl hydroxyisobtyrate;Ethyl hydroxyisobutyrate;Ethyl α-hydroxyisobutyra;ETHYL 2-HYDROXYISOBUTYRATE;Ethyl α-hydroxyisobutyrate;Ethyl 2-hydroxyisobutanoate;Ethyl-a-hydroxy-iso-butyrate;2-methyl-lacticaciethylester
CBNumber:
CB8376602
Molecular Formula:
C6H12O3
Molecular Weight:
132.16
MOL File:
80-55-7.mol
MSDS File:
SDS
Modify Date:
2024/12/18 14:15:30

Ethyl 2-hydroxyisobutyrate Properties

Melting point 78 °C
Boiling point 150 °C (lit.)
Density 0.965 g/mL at 25 °C (lit.)
refractive index n20/D 1.408(lit.)
Flash point 112 °F
storage temp. Flammables area
pka 13.28±0.29(Predicted)
form clear liquid
color Colorless to Almost colorless
BRN 878308
InChI InChI=1S/C6H12O3/c1-4-9-5(7)6(2,3)8/h8H,4H2,1-3H3
InChIKey GFUIDHWFLMPAGY-UHFFFAOYSA-N
SMILES C(OCC)(=O)C(O)(C)C
CAS DataBase Reference 80-55-7(CAS DataBase Reference)
NIST Chemistry Reference Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester(80-55-7)
EPA Substance Registry System Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester (80-55-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02
Signal word  Warning
Hazard statements  H226
Precautionary statements  P210-P370+P378
Hazard Codes  Xi
Risk Statements  10-36/37/38-36/38
Safety Statements  26-36-16
RIDADR  UN 3272 3/PG 3
WGK Germany  3
RTECS  OD5672000
HazardClass  3
PackingGroup  III
HS Code  29181980
NFPA 704
2
2 0

Ethyl 2-hydroxyisobutyrate price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) H0255 Ethyl 2-Hydroxyisobutyrate min. 98.0 % 80-55-7 25G ₹3200 2022-05-26 Buy
TCI Chemicals (India) H0255 Ethyl 2-Hydroxyisobutyrate min. 98.0 % 80-55-7 250G ₹21000 2022-05-26 Buy
Product number Packaging Price Buy
H0255 25G ₹3200 Buy
H0255 250G ₹21000 Buy

Ethyl 2-hydroxyisobutyrate Chemical Properties,Uses,Production

Description

Ethyl 2-hydroxyisobutyrate (E-2HIBA) has a wide range of applications in flavor and fragrance ingredients, green solvents, and pharmaceuticals. E-2HIBA has been synthesized by the batch transesterification of methyl 2-hydroxyisobutyrate with ethanol in the presence of titanium tetraethoxide (reaction conditions: 96 h, yield 97 %) and the esterification of 2-HIBA with an acid catalyst. The direct esterification of 2-HIBA with ethanol using an acid catalyst appears to be a commercially viable approach to produce E-2HIBA [1].

Chemical Properties

clear colorless liquid

Uses

Solvent for nitrocellulose and cellulose acetate; solvent mixture for cellulose ethers, organic synthesis, pharmaceuticals.

References

[1] Sripada, Sarada and James R. Kastner. “Continuous catalytic esterification using a solid acid activated carbon monolith: Comparison of granular and monolith forms with a commercial catalyst.” Chemical Engineering Journal 43 29 (2023): 0.

Global( 164)Suppliers
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GLR Innovations +91 9891111994 New Delhi, India 4535 58 Inquiry
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Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52849 58 Inquiry
ETHYL 2-HYDROXY-2-METHYLPROPIONATE Ethyl hydroxyisobutyrate ETHYL-ALPHA-HYDROXY-ISO-BUTYRATE 2-HYDROXYISOBUTYRIC ACID ETHYL ESTER 2-METHYLLACTIC ACID ETHYL ESTER Methyllactic acid ethyl ester, 2-: (Ethyl 2-hydroxyisobutyrate) Ethyl alpha-hydroxyisobutyrate 98% Ethyl 2-hydroxy-2-methylpropionate 2-Hydroxyisobutyric Acid Ethyl Ester Ethyl 2-hydroxy-2-methylpropionate~Ethyl 2-methyllactate~2-Hydroxyisobutyric acid ethyl ester Ethyl hydroxyisobtyrate Ethyl(Methyl)2-hydroxyisobutyrate Ethyl-a-hydroxy-iso-butyrate Propanoic acid, 2-hydroxy-2-methyl-, ethyl ester Ethyl 2-methyl-2-hydroxypropanoate 2-Hydroxy-2-methylpropanoic acid ethyl ester 2-Hydroxy-2-methylpropionic acid ethyl ester 2-Methyl-2-hydroxypropionic acid ethyl ester Ethyl 2-hydroxyisobutyrate,99% Ethyl α-hydroxyisobu Ethyl α-hydroxyisobutyra Ethyl 2-hydroxy-2-methylpropanaote, Ethyl 2-hydroxyisobutyrate Ethyl 2-hydroxyisobutanoate 2-hydroxy-2-methyl-propanoicaciethylester 2-hydroxyisobutyricacidethylester(alpha-) 2-methyl-lacticaciethylester Ethyl 2-hydroxy-2-methylpropanoate ethyl2-hydroxy-2-methylpropanoate Lactic acid, 2-methyl-, ethyl ester ETHYL 2-METHYLLACTATE ETHYL 2-HYDROXYISOBUTYRATE 12-(2,4,6-trinitroanilino)dodecanoic acid Ethyl2-Hydroxyisobutyrate> Ethyl α-hydroxyisobutyrate Ethyl 2-Hydroxyisobutyrate, ≥ 98.0% 80-55-7 CH32COHCOOC2H5 Organic Building Blocks Esters Building Blocks Carbonyl Compounds C6 to C7 Building Blocks C6 to C7 Carbonyl Compounds Chemical Synthesis Esters Organic Building Blocks Miscellaneous