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(S)-5-Hydroxymethyldihydrofuran-2-one

CAS No.: 32780-06-6

Chemical Name:: (S)-5-Hydroxymethyldihydrofuran-2-one

Synonyms: 5-(Hydroxymethyl)dihydro-2(3H)-furanone;(S)-(+)-γ-Hydroxymethyl-γ(S)-Gamma-Hydroxymethyl-Gamma;(S)-4-HYDROXYMETHYL BUTYROLACTONE;(5S)-5-(hydroxyMethyl)oxolan-2-one;(s)-γ-hydroxymethyl-γ-butyrolactone;(S)-5-Hydroxymethyldihydrofuran-2-on;(S)-(+)-G-HYDROXYMETHYL-G-BUTYROLACTONE;(S)-5-HYDROXYMETHYL-DIHYDRO-FURAN-2-ONE

CBNumber:: CB6702069

Molecular Formula:: C5H8O3

Molecular Weight:: 116.12

MOL File:: 32780-06-6.mol

MSDS File:: SDS

Modify Date:: 2024/8/1 17:24:36

Request For Quotation

(S)-5-Hydroxymethyldihydrofuran-2-one Properties

Melting point	72-74 °C
Boiling point	110-115 °C/0.2 mmHg (lit.)
alpha	56 º (c=3 in chloroform)
Density	1.237 g/mL at 25 °C (lit.)
refractive index	n20/D 1.471(lit.)
Flash point	>230 °F
storage temp.	2-8°C
pka	14.12±0.10(Predicted)
form	clear liquid
color	Colorless to Almost colorless
optical activity	[α]20/D +56°, c = 3 in chloroform
BRN	1680284
CAS DataBase Reference	32780-06-6(CAS DataBase Reference)
NIST Chemistry Reference	(S)-(+)-2',3'-dideoxyribonolactone(32780-06-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

23-24/25-37/39-26

WGK Germany

HS Code

29322090

NFPA 704

	1
0		0

(S)-5-Hydroxymethyldihydrofuran-2-one price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemicals (India)	H0958	(S)-(+)-γ-Hydroxymethyl-γ-butyrolactone min. 94.0 %	32780-06-6	1G	₹8000	2022-05-26	Buy
TCI Chemicals (India)	H0958	(S)-(+)-γ-Hydroxymethyl-γ-butyrolactone min. 94.0 %	32780-06-6	5G	₹28600	2022-05-26	Buy

Product number	Packaging	Price	Buy
H0958	1G	₹8000	Buy
H0958	5G	₹28600	Buy

(S)-5-Hydroxymethyldihydrofuran-2-one Chemical Properties,Uses,Production

Chemical Properties

Colorless to light yellow liqui

Uses

(S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone can be used as a chiral synthon to synthesize:

Potent nucleoside, acetylcholine, and (+)-muricatacin analogs.
Mevinic acids, which are LDL cholesterol-lowering agents.
Adenine based anti-HIV agent named β-F-ddA.

General Description

Dihydro-5-(hydroxymethyl)-2(3H)-furanone is a chiral building block widely used in the synthesis of many natural products and few biologically significant compounds like anti-HIV dideoxynucleosides. It is also used in the synthesis of optically active ligands.

(S)-5-Hydroxymethyldihydrofuran-2-one Preparation Products And Raw materials

Raw materials

Borane-methyl sulfide complex L-Glutamic acid Sodium nitrite Tetrahydrofuran Benzene

Ethyl acetate Hydrochloric acid Methanol PETROLEUM ETHER Pentanoic acid, 4,5-dihydroxy-, methyl ester, (4S)-

D-threo-Pentonic acid, 2-deoxy-, γ-lactone (5S)-5-(trityloxymethyl)-5H-furan-2-one 2-Oxiranepropanoic acid, methyl ester, (2R)- 2-Oxiranepropanoic acid, methyl ester (S)-(+)-GAMMA-(TRITYLOXYMETHYL)-GAMMA-BUTYROLACTONE

(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE (1S,5R)-6,8-dioxabicyclo[3.2.1]octan-4-one

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Preparation Products

(S)-5-Hydroxymethyldihydrofuran-2-one Suppliers

Global( 165)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Clearsynth Labs	91-22-45045900	Maharashtra, India	3889	58	Inquiry
Souvenier Chemicals	08048372762Ext 645	Mumbai, India	396	58	Inquiry
Spectrochem Private Limited	08048372608Ext 246	Maharashtra, India	1056	58	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	China	3957	58	Inquiry
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	China	18648	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32836	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29888	58	Inquiry

Supplier	Advantage
CHEMSWORTH	30
TCI Chemicals (India) Pvt. Ltd.	58
Clearsynth Labs	58
Souvenier Chemicals	58
Spectrochem Private Limited	58
A.J Chemicals	58
Shaanxi Dideu Medichem Co. Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58

(S)-5-Hydroxymethyldihydrofuran-2-one Spectrum

(S)-5-Hydroxymethyldihydrofuran-2-one(32780-06-6)¹HNMR (S)-5-Hydroxymethyldihydrofuran-2-one(32780-06-6)IR

32780-06-6((S)-5-Hydroxymethyldihydrofuran-2-one)Related Search:

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Trimethylolpropane Gamma Butyrolactone (1S)-(-)-Camphanic acid

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(S)-(+)-gamma-Hydroxymethyl-gamma-butyrolactone,97% (S)-Gamma-Hydroxymethyl-Gamma (S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone ,97% (5S)-5-(HYDROXYMETHYL)-3,4,5-TRIHYDROFURAN-2-ONE (5S)-(+)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one (S)-(+)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone (S)-(+)-5-Hydroxymethyltetrahydro-2-furanone 5-Oxo-tetrahydro-furan-2-carboxylic acid ethyl ester (5S)-5-(hydroxyMethyl)oxolan-2-one 2(3H)-Furanone,dihydro-5-(hydroxyMethyl)-, (5S)- (S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone 95% (S)-(+)-&gamma -Hydroxymethyl-&gamma (S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)-2(3H)-FURANONE (S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)FURANONE (S)-(+)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTON (S)-(+)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTONE (S)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTONE (S)-(+)-G-HYDROXYMETHYL-G-BUTYROLACTONE (S)-(+)-4,5-DIHYDRO-5-HYDROXYMETHYL-2(3H)-FURANONE (S)-4,5-DIHYDRO-5-HYDROXYMETHYL-2(3H)-FURANONE DIHYDRO-5-(HYDROXYMETHYL)-2(3H)-FURANONE (S-) 2(3H)-FURANONE, DIHYDRO-5-(HYDROXYMETHYL)-,(S) (S)-4-HYDROXYMETHYL BUTYROLACTONE (S)-5-HYDROXYMETHYL-2-OXOTETRAHYDROFURAN (S)-5-HYDROXYMETHYL-DIHYDRO-FURAN-2-ONE (S)-(+)-5-HYDROXYMETHYL-GAMMA-BUTYROLACTONE (S)-(+)-5-HYDROXYMETHYLTETRAHYDRO-2-FURANONE (S)-γ-Hydroxymethyl-γ-butyrolactone, (S)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone, (S)-5-Hydroxymethyl-2-oxotetrahydrofuran (S)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone, (S)-5-Hydroxymethyl-2-oxotetrahydrofuran (S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)-2(3H)- FURANONE, 95% (98% EE/GLC) (S)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYRO- & (s)-γ-hydroxymethyl-γ-butyrolactone (S)-(+)-5-HYDROXYMETHYL-GAMMA-BUTYROLACTONE 98% (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran (S)-5-Hydroxymethyldihydrofuran-2-on (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone> 5-(Hydroxymethyl)dihydro-2(3H)-furanone (5S)-5-(Hydroxymethyl)dihydro-2(3H)-furanone 32780-06-6 Asymmetric Synthesis Chiral Building Blocks Heterocyclic Building Blocks Furans chiral Chiral Reagent