Difluprednate
- CAS No.
- 23674-86-4
- Chemical Name:
- Difluprednate
- Synonyms
- DFBA;DUREZOL;w6309;myser;CM 9155;Epitopic;Difluprenate;DIFLUPREDNATE;Difluprednate-d3;Difluprednate-d5
- CBNumber:
- CB7458293
- Molecular Formula:
- C27H34F2O7
- Molecular Weight:
- 508.55
- MOL File:
- 23674-86-4.mol
- Modify Date:
- 2024/4/1 18:08:31
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H361 | |||||||||
| Precautionary statements | P501-P202-P201-P280-P308+P313-P405 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | TU3831500 | |||||||||
| HS Code | 2937.29.9095 | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,146mg/kg (146mg/kg),BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)BEHAVIORAL: FOOD INTAKE (ANIMAL),Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 15, Pg. 1066, 1984. | |||||||||
| NFPA 704 |
|
Difluprednate price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | D6288 | 6α,9α-Difluoroprednisolone 21-acetate 17-butyrate ≥98% | 23674-86-4 | 50MG | ₹17633.93 | 2022-06-14 | Buy |
| TCI Chemicals (India) | D5579 | Difluprednate | 23674-86-4 | 50MG | ₹6600 | 2022-05-26 | Buy |
| TCI Chemicals (India) | D5579 | Difluprednate | 23674-86-4 | 250MG | ₹16500 | 2022-05-26 | Buy |
Difluprednate Chemical Properties,Uses,Production
Description
Difluprednate is a synthetic glucocorticoid that potently activates the glucocorticoid receptor (Ki = 78 pM). In vivo, ocular administration of difluprednate (0.05% w/v) increases intraocular pressure in sheep. Formulations containing difluprednate have been used to treat diabetic macular edema and inflammation following cataract surgery.
Chemical Properties
White Solid
Uses
Difluprednate-d3 is the isotope labeled form of Difluprednate (D445925), a corticosteroid (derivative of prednisolone), approved for the treatment of post-operative ocular inflammation.
General Description
Difluprednate, 21-(acetyloxy)-6α,9-difluoro-11β-hydroxy-17-(1-oxobutoxy)pregna-1,4-diene-3,20-dione is being developed (phase III) as a topical ophthalmicemulsion to treat inflammatory eye diseases.
Difluprednate Preparation Products And Raw materials
Global( 196)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Flax Laboratories | +91-9867665132 +91-9867665132 | Maharashtra, India | 44 | 58 | Inquiry |
| Gonane Pharma | +91-9819380043 +91-9819380043 | NaviMumbai, India | 192 | 58 | Inquiry |
| Maharshi Pharma Chem | +91-7940359347 +91-7433927173 | Gujarat, India | 24 | 58 | Inquiry |
| BDR Pharmaceuticals International Pvt Ltd | +91-2240560560 +91-7718884418 | Maharashtra, India | 206 | 58 | Inquiry |
| Vijaya Pharma And Life Science | +91-8939866271 +91-8939866271 | Tamil Nadu, India | 320 | 58 | Inquiry |
| Symbiotec Pharma Lab Pvt Ltd | +91-7316676406 +91-7316676405 | Madhya Pradesh, India | 71 | 58 | Inquiry |
| Swati Spentose Pvt Ltd | +91-2261505232 +91-2261505232 | Maharashtra, India | 44 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
23674-86-4(Difluprednate)Related Search:
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4-diene-3,20-dione,6-alpha,9-difluoro-11-beta,17,21-trihydroxy-pregna-21-a
6-alpha,9-alpha-difluoroprednisolone17-butyrate21-acetate
cetate,17-butyrate
myser
w6309
6a,9a-difluoroprednisolone 21-acetate 17-butyrate
6ALPHA,9ALPHA-DIFLUOROPREDNISOLONE 21-ACETATE 17-BUTYRATE
DIFLUPREDNATE
6α,9-Difluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-butyrate
6α,9-Difluoroprednisolone 21-acetate 17-butyrate
6α,9α-Difluoroprednisolone 21-acetate 17-butyrate
Butyric acid, 17-ester with 6α,9-difluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate (8CI)
CM 9155
Epitopic
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)-, (6α,11β)-
Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,17,21-trihydroxy-, 21-acetate 17-butyrate (8CI)
6a,9-Difluoro-11b,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate 17-butyrate
21-Acetyloxy-6α,9-difluoro-11β-hydroxy-17-(1-oxobutoxy)pregna-1,4-diene-3,20-dione
(6α,11β)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)-pregna-1,4-diene-3,20-dione
6a,9-Difluoro-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione 21-Acetate 17-Butyrate
Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)-, (6a,11b)-
Difluprednate-d3
(6α,11β)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)pregna-1,4-diene-3,20-dion
Difluprednate-d5
Difluoroprednisolone butyrate acetate
Difluprednate Solution, 100μg/mL
Difluprednate USP/EP/BP
Difluprednate(DFBA)
(6α,11β)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-17-(1-oxobutoxy)-pregna-1,4-diene-3,20-dione
DifluprednateQ: What is
Difluprednate Q: What is the CAS Number of
Difluprednate Q: What is the storage condition of
Difluprednate Q: What are the applications of
Difluprednate
DFBA
DUREZOL
[(6S,8S,9R,10S,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-6,9-difluoro-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate
Difluprenate
cetate,Chemicalbook17-butyrate
6α,9α-Difluorprednisolon-17-butyrat-21-acetat
Myser|||Epitopic|||CM 9155
23674-86-4
23674-68-4
C27H34F2O7
Inhibitors
Intermediates & Fine Chemicals
Pharmaceuticals
Steroids
23674-86-4