Isoflupredone Acetate

Isoflupredone Acetate Structure
CAS No.
338-98-7
Chemical Name:
Isoflupredone Acetate
Synonyms
predef;U-6013;biorinil;NSC 12600;NSC 37977;Predef R 2X;IsoflupredineAcetate;21-Acetoxy-9-fluoro-;Isoflupredone acetate;Nintedanib Impurity 156
CBNumber:
CB9500538
Molecular Formula:
C23H29FO6
Molecular Weight:
420.47
MOL File:
338-98-7.mol
MSDS File:
SDS
Modify Date:
2024/3/28 13:39:29

Isoflupredone Acetate Properties

Melting point 244-246° (dec)
alpha D23 +108° (c = 0.735 in dioxane)
Boiling point 576.5±50.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Acetone (Slightly, Sonicated), DMSO (Slightly), Methanol (Slightly), Ethanol (Slightly)
form Solid
pka 12.05±0.70(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501
HS Code  2937220000

Isoflupredone Acetate Chemical Properties,Uses,Production

Uses

Isoflupredone Acetate is an anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.

Veterinary Drugs and Treatments

Isoflupredone acetate is a potent glucocorticoid and like other glucocorticoids can be used for its antiinflammatory or immunosuppressive effects. Labeled indications for isoflupredone include: adjunctive treatment of bovine ketosis, alleviating pain and lameness associated with musculoskeletal conditions, acute hypersensitivity reactions, adjunctive treatment of overwhelming infections with severe toxicity, shock, supportive therapy in the treatment of stress conditions (e.g., surgery), dystocia, retained placenta, inflammatory ocular conditions, snakebite and parturient paresis.
In horses, isoflupredone has been used parenterally to reduce inflammation associated with recurrent airway obstruction (RAO, “heaves”, COPD).
While the drug could be used in small animals, it is recommended to use other glucocorticoid agents instead, where there has been more experience and other approved products for dogs and cats are available.

Isoflupredone Acetate Preparation Products And Raw materials

Global( 96)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Coral Drugs Pvt Ltd +91-1244518100 +91-8199986118 New Delhi, India 24 58 Inquiry
Horster Biotek Pvt Ltd +91-7359657360 +91-9898127219 Gujarat, India 58 58 Inquiry
Ralington Pharma +91-7948911722 +91-9687771722 Gujarat, India 1350 58 Inquiry
Maharshi Pharma Chem +91-7940359347 +91-7433927173 Gujarat, India 24 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Samex Overseas 08068441146Ext 740 Gujarat, India 124 58 Inquiry
Pellucid Pharma 08048371509Ext 991 Ahmedabad, India 23 58 Inquiry

Isoflupredone Acetate Spectrum

4-diene-3,20-dione,21-(acetyloxy)-9-fluoro-11,17-dihydroxy-pregna-(11-be 4-diene-3,20-dione,9-fluoro-11-beta,17,21-trihydroxy-pregna-21-acetate 9-alpha-fluoroprednisoloneacetate 9-fluoroprednisoloneacetate 9-fluorprednisoloneacetate biorinil predef ISOFLUPREDONE ACETATE (200 MG) isoflupredone 21-acetate 21-Acetoxy-9-fluoro-11,B-17-dihydroxy-pregna-1,4-diene-3,20-dione IsoflupredineAcetate 21-ACETOXY-9-FLUORO-11BETA,17-DIHYDROXY-PREGNA-1,4-DIENE-3,20-DIONE Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11.beta.)- 21-acetoxy-9-fluoro-11,17-dihydroxy-pregna-1,4-diene-3,20-dione Isoflupredone acetate 21-ACETOXY-9-FLUORO-11SS,17-DIHYDROXY-PREGNA-1,4-DIENE-3,20-DIONE 21-(Acetyloxy)-9α-fluoro-11β,17α-dihyroxypregna-1,4-diene-3,20-dione U-6013 21-Acetoxy-9-fluoro- 9-Fluoroprednisolone-21-acetate NSC 12600 NSC 37977 Predef R 2X 2-((8S,9R,10S,11S,13S,14S,17R)-9-fluoro-11,17-dihydroxy-10,13-diMethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate Isoflupredone Acetate USP 9alpha-Fluoro-11beta,17alpha,21-trihydroxypregna-1,4-diene-3,20-dione 21-acetate Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-9-fluoro-11,17-dihydroxy-, (11β)- Isoflupredone Acetate USP/EP/BP Isoflupredone Acetate (1348907) Isofluprednisone acetate 9-Fluoroprednisolone acetate(Isoflupredone acetate) 21-Acetoxy-9-fluoro-11b,17-dihydroxypregna-1,4-dienen-3,20-dione Nintedanib Impurity 156 1, 4-PREGNADIEN-9α-FLUORO-11β, 17, 21-TRIOL-3, 20-DIONE 21-ACETATE 338-98-7 Intermediates & Fine Chemicals Pharmaceuticals Steroids