1-Phenyl-2-propen-1-one

1-Phenyl-2-propen-1-one Structure
CAS No.
768-03-6
Chemical Name:
1-Phenyl-2-propen-1-one
Synonyms
1-phenylprop-2-en-1-one;acrylophenone;2-propenophenone;phenylvinylketone;1-phenyl-2-propen-;ketone,phenylvinyl;1-Phenyl-2-propen-1-;3-oxo-3-phenylpropene;Fluoxetine Impurity 8;Phenylhexol impurity 7
CBNumber:
CB7504082
Molecular Formula:
C9H8O
Molecular Weight:
132.16
MOL File:
768-03-6.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

1-Phenyl-2-propen-1-one Properties

Boiling point 204.08°C (rough estimate)
Density 1.0270 (rough estimate)
refractive index 1.5181 (estimate)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
form Oil
color Clear Colorless to Pale Yellow
Stability Light and Temperature Sensitive
NIST Chemistry Reference 2-Propen-1-one, 1-phenyl-(768-03-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P280-P301+P312-P362+P364
HS Code  2914390090

1-Phenyl-2-propen-1-one Chemical Properties,Uses,Production

Uses

1-Phenyl-2-propen-1-one is a chemical reagent used in the synthesis of pharmaceutical agents. Used in the preparation of functionalized aminoindolizines as well as pyrano[3,2-x]coumarins.

Synthesis Reference(s)

The Journal of Organic Chemistry, 38, p. 1602, 1973 DOI: 10.1021/jo00948a033
Synthetic Communications, 23, p. 543, 1993 DOI: 10.1080/00397919308009811

Safety Profile

A poison by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also KETONES.

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2-propenophenone ketone,phenylvinyl phenylvinylketone 1-phenyl-2-propen-1-one 3-oxo-3-phenylpropene 1-Phenyl-2-propen-1- Trihexyphenidyl impurity 7 1-phenyl-2-propen- 1-Phenyl-2-propen-1-one (Contains ~1% BHT as stabilizer) Fluoxetine intermediate FXT-1b 2-Propen-1-one, 1-phenyl- Fluoxetine Impurity 8 acrylophenone 1-phenylprop-2-en-1-one 4-Isoxazoleethanol,3,6-dimethyl- Dapoxetine Impurity 48 (Contains ~1% BHT as stabilizer) Phenylhexol impurity 11 Phenylhexol impurity 7 Penicillamine Impurity 13 1-Phenylprop-2-en-1-one (Contains stabilizer) 768-03-6