ethiazide

ethiazide Structure
CAS No.
1824-58-4
Chemical Name:
ethiazide
Synonyms
Salta;Etizide;ethiazide;Eclotizide;aethiazidum;Eclotizidum;Neo Diuresal;6-Chloro-3-ethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;6-chloro-3-ethyl-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide;2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-ethyl-3,4-dihydro-, 1,1-dioxide
CBNumber:
CB7939138
Molecular Formula:
C9H12ClN3O4S2
Molecular Weight:
325.79
MOL File:
1824-58-4.mol
Modify Date:
2024/10/28 16:48:35

ethiazide Properties

Melting point 269-270°
Boiling point 563.5±60.0 °C(Predicted)
Density 1.526±0.06 g/cm3(Predicted)
pka 9.01±0.40(Predicted)

ethiazide Chemical Properties,Uses,Production

Originator

Ethiazide,Tokyo Tanabe,Japan,1970

Manufacturing Process

A mixture of 2.9 grams of 5-chloro-2,4-disulfamyl-aniline in 20 ml of anhydrous diethylene glycoldimethylether, 0.44 gram of propionaldehyde and 0.5 ml of a solution of hydrogen chloride in ethyl acetate (109.5 grams hydrogen chloride per 1,000 ml) is heated to 80° to 90°C and maintained at that temperature for 1 hour. The reaction mixture is concentrated under reduced pressure; on addition of water, the product separates and is then recrystallized from ethanol or aqueous ethanol to yield the desired 6-chloro-3- ethyl-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide, MP 269° to 270°C.

Therapeutic Function

Diuretic, Cardiotonic, Smooth muscle relaxant, Respiratory stimulant

ethiazide Preparation Products And Raw materials

ethiazide Suppliers

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Matrix Scientific 803 788-9494 All other calls United States 6632 80 Inquiry
6-Chloro-3-ethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide Eclotizide Etizide Neo Diuresal Salta 6-chloro-3-ethyl-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide 6-chloro-3-ethyl-1,1-dioxo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide ethiazide aethiazidum 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3-ethyl-3,4-dihydro-, 1,1-dioxide Eclotizidum 1824-58-4