MELPERONE

MELPERONE Structure
CAS No.
3575-80-2
Chemical Name:
MELPERONE
Synonyms
FG 5111;Buronil;Melperon;metylperon;Flubuperone;Melperone >Melperone,Inhibitor,inhibit;Melperone (base and/or unspecified salts);4-Fluoro-γ-(4-Methylpiperidino)butyrophenone;γ-(4-Methylpiperidino)-p-fluorobutyrophenone
CBNumber:
CB81011889
Molecular Formula:
C16H22FNO
Molecular Weight:
263.35
MOL File:
3575-80-2.mol
Modify Date:
2023/9/20 16:43:00

MELPERONE Properties

Melting point 78.0 to 82.0 °C
Boiling point bp0.1 120-125°
Density 1.046±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 41.67 mg/mL (158.23 mM)
pka 9.34±0.10(Predicted)
form powder to crystal
color White to Light yellow to Light orange
Merck 14,5827

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H332-H319-H312
Precautionary statements  P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P264-P280-P305+P351+P338-P337+P313P-P280-P302+P352-P312-P322-P363-P501
HS Code  2933.39.3100

MELPERONE price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) M2622 Melperone min. 95.0 % 3575-80-2 25MG ₹5400 2022-05-26 Buy
TCI Chemicals (India) M2622 Melperone min. 95.0 % 3575-80-2 100MG ₹14600 2022-05-26 Buy
Product number Packaging Price Buy
M2622 25MG ₹5400 Buy
M2622 100MG ₹14600 Buy

MELPERONE Chemical Properties,Uses,Production

Originator

Eunerpan,Nordmark,W. Germany,1965

Manufacturing Process

A solution or dispersion consisting of 20.1 g (0.1 mol) of γ-chloro-pfluorobutyrophenone, 19.8 g (0.2 mol) of 4-methylpiperidine and 0.1 g of potassium iodide in 150 ml toluene is heated in a sealed glass tube for 15 hours at 100°C to 110°C. The potassium iodide and the 4-methylpiperidine hydrochloride formed in the reaction are separated by filtration and the solvent removed from the filtrate by evaporation in vacuum on a steam bath. The residue is distilled and the fraction obtained at 120°C to 125°C and at a pressure lower than 0.1 mm Hg is collected. The base is dissolved in ether and the 4-fluoro-γ-(4-methylpiperidino)-butyrophenone precipitated as the hydrochloride. The reaction product is purified by recrystallization in ethanol/ether.
Yield 22.0 g (73% of theory). MP 209°C to 211°C.

Therapeutic Function

Neuroleptic

MELPERONE Preparation Products And Raw materials

Raw materials

Preparation Products

MELPERONE Suppliers

Global( 40)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Career Henan Chemica Co +86-0371-86658258 +8613203830695 China 30253 58 Inquiry
AFINE CHEMICALS LIMITED +86-0571-85134551 China 15395 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
Alfa Chemistry +1-5166625404 United States 21317 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry

MELPERONE Spectrum

metylperon Melperone (base and/or unspecified salts) 1-(4-Fluorophenyl)-4-(4-methylpiperidin-1-yl)-1-butanone Melperon 1-(4-Fluorophenyl)-4-(4-methylpiperidin-1-yl)butan-1-one 1-(4-Fluorophenyl)-4-(4-Methyl-1-piperidinyl)-1-butanone 4'-Fluoro-4-(4-Methylpiperidino)butyrophenone 4-Fluoro-γ-(4-Methylpiperidino)butyrophenone Buronil FG 5111 Flubuperone γ-(4-Methylpiperidino)-p-fluorobutyrophenone Melperone > 1-Butanone, 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)- Melperone,Inhibitor,inhibit 3575-80-2 C16H22FNO