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RUBRATOXINA

RUBRATOXINA Structure
CAS No.
22467-31-8
Chemical Name:
RUBRATOXINA
Synonyms
RUBRATOXINA;10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione;9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride;1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel-
CBNumber:
CB81405198
Molecular Formula:
C26H32O11
Molecular Weight:
520.528
MOL File:
22467-31-8.mol
Modify Date:
2023/6/30 15:45:59
Request For Quotation

RUBRATOXINA Properties

Melting point 210-214℃ (decomposition)
storage temp. Store at -20°C
solubility Acetonitrile: soluble; DMSO: soluble
form A powder
color White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
NFPA 704
0
2 0

RUBRATOXINA Chemical Properties,Uses,Production

Description

Rubratoxin A is a natural mycotoxin and competitive inhibitor of protein phosphatase 2A (PP2A; IC50 = 170 nM). It has no significant effect on several other phosphatases, including PP1, PP2B, and protein tyrosine phosphatase 1B. Rubratoxin A drives overphosphorylation of PP2A substrate proteins in cultured cells treated for three hours at 20 μM. It causes suppression of tumor metastasis and reduction of primary tumor volume in mouse xenografts.

Uses

Rubratoxin A is a potent and selective competitive PP2A inhibitor.

RUBRATOXINA Preparation Products And Raw materials

Raw materials

Preparation Products

RUBRATOXINA Suppliers

Global( 17)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28091 58 Inquiry
Cayman Chemical Company (800) 364-9897 United States 6618 81 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9707 58 Inquiry
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 China 29803 58 Inquiry
Santa Cruz Biotechnology, Inc. +1 (831) 457-3800 United States 3602 60 Inquiry
Glentham Life Sciences +44 (2033) 978-798 United Kingdom 1429 0 Inquiry
Shanghai Tauto Biotech Co., Ltd. 021-51320588 China 3989 66 Inquiry
Supplier Advantage
TargetMol Chemicals Inc. 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
Aladdin Scientific 58
TargetMol Chemicals Inc. 58
Cayman Chemical Company 81
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Maclean Biochemical Technology Co., LTD 58
Santa Cruz Biotechnology, Inc. 60
Glentham Life Sciences 0
Shanghai Tauto Biotech Co., Ltd. 66

22467-31-8(RUBRATOXINA)Related Search:

RUBRATOXINA 2,3-Dimethylmaleic anhydride DIMETHYL DECADIENAL 4-METHYLPENTANOIC ANHYDRIDE 2,4-DIMETHYL-2,6-HEPTADIEN-1-OL
(+/-)-LAVANDULOL 2,5-DIMETHYL-1,5-HEXADIEN-3-OL 5-HYDROXY-4-METHYL-2(5H)FURANONE 2-Isopropyl-5-methyl-2-hexenal (CIS)-8-METHYLNON-6-ENOIC ACID
GERANIC ACID
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RUBRATOXINA 10-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-(1-hydroxyheptyl)-1H-cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione 9-[(3,6-Dihydro-6-oxo-2H-pyran-2-yl)hydroxymethyl]-3,4,5,8,9,10-hexahydro-1,5-dihydroxy-4-(1-hydroxyheptyl)-3-oxo-1H-cyclonona[c]furan-6,7-dicarboxylic anhydride 1H-Cyclonona[1,2-c:5,6-c']difuran-1,3,6-trione, 10-[(R)-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]hydroxymethyl]-4,5,8,9,10,11-hexahydro-4,8-dihydroxy-5-[(1S)-1-hydroxyheptyl]-, (4S,5R,10R)-rel- 22467-31-8