CI 1020

CI 1020 Structure
CAS No.
162256-50-0
Chemical Name:
CI 1020
Synonyms
CI 1020;PD 156707;3-(1,3-Benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-2(5H)-furanone;2(5H)-Furanone, 3-(1,3-benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-
CBNumber:
CB81873005
Molecular Formula:
C28H26O9
Molecular Weight:
506.5
MOL File:
162256-50-0.mol
Modify Date:
2023/5/18 11:31:04

CI 1020 Properties

storage temp. Store at +4°C
solubility Soluble to 50 mM in DMSO
form Powder

CI 1020 Chemical Properties,Uses,Production

Uses

A novel endothelin-A receptor antagonist, in hypoxic pulmonary hypertension.

Biological Activity

Highly selective, orally active, non-peptide endothelin-A receptor (ET A ) antagonist (IC 50 values are 0.3 and 480 nM for ET A and ET B receptors respectively). Antihypertensive; blocks ET-1-induced pressor responses following oral administration.

CI 1020 Preparation Products And Raw materials

Raw materials

Preparation Products

CI 1020 Suppliers

Global( 29)Suppliers
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TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 52927 58 Inquiry
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 China 4552 58 Inquiry
BOC Sciences 1-631-485-4226; 16314854226 United States 14059 65 Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 China 15848 69 Inquiry
Toronto Research Chemicals +1 (416) 665-9696 Canada 6088 71 Inquiry
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 China 94717 76 Inquiry
Shanghai Zhixin Chemical Technology Co., Ltd. 021-60441077 18701958033 China 572 58 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 China 56070 58 Inquiry
Tocris Bioscience +44 (0) 117 916 3333 United Kingdom 5729 77 Inquiry
3-(1,3-Benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]-2(5H)-furanone CI 1020 PD 156707 2(5H)-Furanone, 3-(1,3-benzodioxol-5-yl)-5-hydroxy-5-(4-methoxyphenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]- 162256-50-0 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals