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(R)-(-)-3-Chloro-1,2-propanediol

(R)-(-)-3-Chloro-1,2-propanediol Structure
CAS No.
57090-45-6
Chemical Name:
(R)-(-)-3-Chloro-1,2-propanediol
Synonyms
(R)-3-CHLOROPROPANE-1,2-DIOL;(R)-3-CHLORO-1,2-PROPANEDIOL;2-propanediol;(R)-3-ChL;(R)-3-MCPD;(R)-(-)-3-Chloro-1;R-Chloropropanediol;oro-1,2-propanedioL;(R)-(-)-3-Chloro-1,2;Panthenol 16485-10-2
CBNumber:
CB8194510
Molecular Formula:
C3H7ClO2
Molecular Weight:
110.54
MOL File:
57090-45-6.mol
MSDS File:
SDS
Modify Date:
2024/7/30 16:49:16

(R)-(-)-3-Chloro-1,2-propanediol Properties

Melting point -40°C
Boiling point 213 °C(lit.)
alpha -0.9 º (neat)
Density 1.321 g/mL at 20 °C(lit.)
vapor pressure 0.04 mm Hg ( 25 °C)
refractive index n20/D 1.48(lit.)
Flash point >230 °F
storage temp. Inert atmosphere,2-8°C
solubility soluble in Chloroform, Methanol
form clear liquid
pka 13.28±0.20(Predicted)
Specific Gravity 1.322
color Colorless to Brown
optical activity [α]20/D 1°, neat
Water Solubility soluble
BRN 2202928
InChIKey SSZWWUDQMAHNAQ-VKHMYHEASA-N
LogP 0.5 at 25℃
CAS DataBase Reference 57090-45-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS06,GHS08
Signal word  Danger
Hazard statements  H290-H301-H315-H318-H330-H351-H360FD-H370-H372
Precautionary statements  P202-P234-P280-P302+P352-P304+P340+P310-P305+P351+P338
Hazard Codes  T
Risk Statements  25-41-68-62-36/37/38-23/25-21
Safety Statements  26-28-39-45-36/37/39
RIDADR  UN 2689 6.1/PG 3
WGK Germany  3
RTECS  TY4025000
3
HazardClass  6.1
PackingGroup  III
HS Code  29053200
NFPA 704
0
4 1

(R)-(-)-3-Chloro-1,2-propanediol price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) M0967 (R)-(-)-3-Chloro-1,2-propanediol min. 96.0 % 57090-45-6 10G ₹4400 2022-05-26 Buy
TCI Chemicals (India) M0967 (R)-(-)-3-Chloro-1,2-propanediol min. 96.0 % 57090-45-6 25G ₹7900 2022-05-26 Buy
Product number Packaging Price Buy
M0967 10G ₹4400 Buy
M0967 25G ₹7900 Buy

(R)-(-)-3-Chloro-1,2-propanediol Chemical Properties,Uses,Production

Chemical Properties

clear light yellow liquid

Uses

(R)-(-)-3-Chloro-1,2-propanediol is used as a reagent in the synthesis of PA-824, which is a promising antituberculosis drug candidate that has been synthesized. It is also used in the manufacture of L-carnitine, which is a quaternary ammonium compound involved in metabolism in most mammals, plants, and some bacteria.

Definition

ChEBI: The (R)-stereoisomer of 3-chloro-1,2-propanediol.

Health Hazard

The toxicological evaluation revealed that (R)-(-)-3-Chloro-1,2-propanediol was genotoxic in humans and had anti-fertility effects in male rats. The discharge of this compound into wastewater might cause serious environmental hazards[1].

References

[1] Yun‐Xu Yang. “Practical and Efficient Utilisation of (R)-3-chloro-1,2-Propanediol in Synthesis of L-Carnitine.” Journal of Chemical Research-s 93 1 (2011): 371–372.

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(R)-3-CHLORO-1,2-PROPANEDIOL ,98%MIN (R)-(-)-3-Chloro-1,2-propanediol,98% (R)-(-)-3-Chloro-1 R(-)3-Chloro-1,3-propanediol 1,2-Propanediol, 3-chloro-, (2R)- (R)-(-)-3-Chloro-1,2-propanediol, ee: 99% (R)-(-)-alpha-Chlorohydrin Glycerol (R)-(-)-alpha-Monochlorohydrin (R)-(-)-alpha-Monochlorohydrin (R)-(-)-3-Chloro-1,2 (R)-3-Chloro-1,2-propanediol, 95+% R - 3 - chloro - 1, 2 - propylene glycol (R)-(-)-3-Chloro-1,2-propanediol (2R)-3-chloro-1,2-propanediol GLYCEROL (R)-(-)-ALPHA-MONOCHLOROHYDRIN (R)-GLYCEROL ALPHA-MONOCHLOROHYDRIN (R)-(-)-ALPHA-CHLOROHYDRIN (R)-ALPHA-GLYCEROL CHLOROHYDRIN (R)-(-)-ALPHA-MONOCHLOROHYDRIN (R)-(-)-3-CHLORO-1,2-PROPANEDIOL (R)-(-)-3-GLYCEROL ALPHA-MONOCHLOROHYDRIN (2R)-3-CHLOROPROPANE-1,2-DIOL (R)-(-)-3-Chloro-1,2-propanediol 97%, optical purity ee: 98% (GLC) (R)-α-Glycerol chlorohydrin (R)-(-)-3-Glycerol alpha-monochlorohydrin (R)-(-)-alpha-Monochlorohydrin Chloropropanediol,98% (R)/(S)-3-Chloro-1,2-Propanediol (-)-α-monochlorohydrine (R)-3-MCPD (R)-(-)-3-Chloro-1,2-propanediol, 97%, ee 98% R-Chloropropanediol (R)-(-)-3-CHLORO-1,2-PROPANEDIOL , EE 98% R-3-CHLOROPROPANE DIOL (R)-3-ChL oro-1,2-propanedioL (R)-3-Chloro-1,2-propanediol cas 57090-45-6 (R)-(-)-3-Chloro-1,2-propanediol> (R)-(-)-3-Chloro-1,2-propanedi Epichlorohydrin Impurity 6 (R)-(-)-3-CHLORO-1,2-PROPANEDIOL 57090-45-6 (R)-(-)-3-CHLORO-l,2-PROPANEDIOL (R)-(-)-3-Chloro-1,2-propanediol, 98%, ee: 99% (R)-Chloro-1,2-propanediol 2-propanediol (R)-3-CHLOROPROPANE-1,2-DIOL (R)-3-CHLORO-1,2-PROPANEDIOL (R)-α-Glycerol chlorohydrin Panthenol 16485-10-2 R-(-)-3-Chloro-1,2-propanediol R-3-Chloropropanediol (R)-(-)-3-CHLORO-1,2-PROPANEDIAL (R)-(-)-3-Chloro-1,2-propanediol,NA Quizalofop Impurity 4 57090-45-6 57095-45-6 57090-46-9 57094-45-6 ClC3H7O2 C3H7ClO2 Polyols Organic Building Blocks Asymmetric Synthesis