1-Phenoxy-2-propanol
- CAS No.
- 770-35-4
- Chemical Name:
- 1-Phenoxy-2-propanol
- Synonyms
- PROPYLENE GLYCOL PHENYL ETHER;1-PHENOXYPROPAN-2-OL;Phenoxyisopropanol;DOWANOL®DOWANOL? PPh;AURORA KA-7000;1-Phenoxy-2-pr;DOWANOL(TM) PPH;PHENOXY PROPANOL;1-phenoxy-2-propano
- CBNumber:
- CB4100744
- Molecular Formula:
- C9H12O2
- Molecular Weight:
- 152.19
- MOL File:
- 770-35-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/31 13:51:23
| Melting point | 11 °C |
|---|---|
| Boiling point | 243 °C (lit.) |
| Density | 1.064 g/mL at 20 °C (lit.) |
| vapor pressure | 1Pa at 20℃ |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Refrigerator |
| solubility | water: soluble15.1g/L at 20°C |
| pka | 14.43±0.20(Predicted) |
| form | Oil |
| color | Clear Colourless |
| Specific Gravity | 1.051 |
| Water Solubility | 15.1g/L at 20℃ |
| BRN | 1941356 |
| Stability | Stable. Flammable. Incompatible with strong oxidizing agents. |
| LogP | 1.41 at 24.1℃ |
| CAS DataBase Reference | 770-35-4(CAS DataBase Reference) |
| NIST Chemistry Reference | 1-Phenoxy-2-propanol(770-35-4) |
| EPA Substance Registry System | 1-Phenoxy-2-propanol (770-35-4) |
1-Phenoxy-2-propanol price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 484423 | 1-Phenoxy-2-propanol ≥93% | 770-35-4 | 1L | ₹4957.85 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 484423 | 1-Phenoxy-2-propanol ≥93% | 770-35-4 | 5L | ₹16140.08 | 2022-06-14 | Buy |
| TCI Chemicals (India) | P0118 | 1-Phenoxy-2-propanol min. 95.0 % | 770-35-4 | 25ML | ₹2400 | 2022-05-26 | Buy |
| ALFA India | ALF-L04596-30 | 1-Phenoxy-2-propanol, tech. 85% | 770-35-4 | 250g | ₹5530 | 2022-05-26 | Buy |
| TCI Chemicals (India) | P0118 | 1-Phenoxy-2-propanol min. 95.0 % | 770-35-4 | 500ML | ₹22900 | 2022-05-26 | Buy |
1-Phenoxy-2-propanol Chemical Properties,Uses,Production
Chemical Properties
colourless liquid
Uses
1-Phenoxy-2-propanol is a useful synthetic intermediate. It was used in the preparation of acylarylthiocarbamates as nonnucleoside reverse transcriptase inhibitors.
Definition
Colorless liquid.Combustible.
Application
1-Phenoxy-2-propanol (PP) is used as a preservative in cosmetics. PP is currently permitted for up to 1% in cosmetic formulations in Korea and Europe. In addition to its cosmetic uses, PP is used as a solvent for mixing water and organic components in paints, coatings, and films. It is used as an ink solvent for industrial paints, ballpoint pens, stamp pads, and paint removers. The exposure range is broad since PP is used in various industrial paints and cosmetic
General Description
1-Phenoxy-2-propanol (PP), a gycol ether, can be synthesized by reacting propylene oxide with phenol in the presence of Al2O3-MgO/Fe3O4 catalyst. The influence of its anesthetic property on gastropods has been analyzed. Its degradation by microorganisms in different soil types has been investigated.
Safety Profile
Moderately toxic by ingestion and skin contact. Experimental reproductive effects. When heated to decompositionit emits acrid smoke and irritating vapors.
Toxicity evaluation
1-Phenoxy-2-propanol (PP) does not cause skin irritation or sensitization. However, it may induce mucosal irritation. The pregnant Himalayan rabbits were orally administered 0, 60, 180, and 540?mg/kg/day of PP during organogenesis (7–19 days of pregnancy). LOAEL (Lowest Observed Adverse Effect Level) for maternal toxicity was assessed at 540?mg/kg/day based on weight loss and apathy. In addition, LOAEL for developmental toxicity was 540?mg/kg/day, and NOAEL (No Observed Adverse Effect Level) was assessed at 180?mg/kg/day. The other study reported that NOAEL for maternal toxicity of PP orally treated to pregnant Wistar rats was 40?mg/kg/day, and NOAEL for developmental toxicity of PP was 160?mg/kg/day.
Regulations
1-Phenoxy-2-propanol (PP) has antibacterial properties and is designated as a sterilizing and preserving agent used in cosmetics and soaps. In Korea, PP comprises up to 1.0% of formulations and is only allowed in products that are washed off after use, and other products are prohibited. European Commission (EC) restricts washing products to 1.0% or less[1].
References
[1] Jung Dae Lee . “Percutaneous permeability of 1-phenoxy-2-propanol, a preservative in cosmetics.” Regulatory Toxicology and Pharmacology 103 (2019): Pages 56-62.
1-Phenoxy-2-propanol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| LANXESS India Pvt. Ltd. | +91-8356878763 +91-8356878763 | Maharashtra, India | 190 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| KD Cleaning Solution | 08048250291Ext 381 | Gujarat, India | 1 | 58 | Inquiry |
| Camex Speciality Private Limited | 08046051668 | Ahmedabad, India | 117 | 58 | Inquiry |
| LANXESS India Pvt. Ltd. | +91-22-2587 1000 | Maharashtra, India | 131 | 58 | Inquiry |
| Liaoning Kelong Fine Chemical Co., Ltd | +86-0419-5589997 +86-13224191133 | China | 3 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| LANXESS India Pvt. Ltd. | 58 |
| CHEMSWORTH | 30 |
| CLEARSYNTH LABS LTD. | 58 |
| TCI Chemicals (India) Pvt. Ltd. | 58 |
| Otto Chemie Pvt. Ltd. | 58 |
| Alfa Aesar | 58 |
| KD Cleaning Solution | 58 |
| Camex Speciality Private Limited | 58 |
| LANXESS India Pvt. Ltd. | 58 |
| Liaoning Kelong Fine Chemical Co., Ltd | 58 |
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