TYRPHOSTIN B44
![TYRPHOSTIN B44 Structure](CAS/GIF/133550-32-0.gif)
- CAS No.
- 133550-32-0
- Chemical Name:
- TYRPHOSTIN B44
- Synonyms
- AG 527;Zinc03871437;TYRPHOSTIN B44;TYRPHOSTIN AG 527;TRYPHOSTIN AG 527;TYRPHOSTIN B44(-);Reaxys ID: 4356230;ALPHA-CYANO-(-)-(R)-N-(ALPHA-PHENETHYL)-3,4-DIHYDROXYCINNAMIDE;(-)-(r)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide;(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE
- CBNumber:
- CB8197102
- Molecular Formula:
- C18H16N2O3
- Molecular Weight:
- 308.33
- MOL File:
- 133550-32-0.mol
- Modify Date:
- 2023/5/18 11:31:14
TYRPHOSTIN B44 Chemical Properties,Uses,Production
Uses
Tyrphostin B44, (-) enantiomer is a potent inhibitor of (EGFR) kinase.
Biological Activity
Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC 50 = 0.4 μ M), more active than the (+) enantiomer ((S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). Selective over ErbB2.
TYRPHOSTIN B44 Preparation Products And Raw materials
Raw materials
Preparation Products
TYRPHOSTIN B44 Suppliers
Global( 35)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Amadis Chemical Company Limited | 571-89925085 | China | 131980 | 58 | Inquiry |
Energy Chemical | 021-58432009 400-005-6266 | China | 44843 | 58 | Inquiry |
Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | China | 9707 | 58 | Inquiry |
Beijing Haite lesk Technology Co., Ltd | 15210893940; 15116916250 | China | 7328 | 58 | Inquiry |
BOC Sciences | 1-631-485-4226; 16314854226 | United States | 14059 | 65 | Inquiry |
WEITIXIHAUGONG | 0371-53370800 18037197114 | China | 10002 | 58 | Inquiry |
EMD Biosciences, Inc. | 858 450 5500 | United States | 6529 | 66 | Inquiry |
Fluorochem Ltd. | +44 1457 868921 | United Kingdom | 6406 | 74 | Inquiry |
VWR International | 800 932 5000 | United Kingdom | 6554 | 82 | Inquiry |
Spectrum Chemicals & Laboratory Products | 310 516 8000 | United States | 6706 | 77 | Inquiry |
133550-32-0(TYRPHOSTIN B44)Related Search:
(R)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE
(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE
(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE
TYRPHOSTIN AG 527
TYRPHOSTIN B44
TYRPHOSTIN B44(-)
TRYPHOSTIN AG 527
AG 527
ALPHA-CYANO-(-)-(R)-N-(ALPHA-PHENETHYL)-3,4-DIHYDROXYCINNAMIDE
(-)-(r)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
Tyrphostin B44, (-)-(R)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide
Zinc03871437
(E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]-2-propenamide
Reaxys ID: 4356230
2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]-, (2E)-
133550-32-0
BioChemical
Cell Signaling and Neuroscience
Cell Biology
Receptor Tyrosine Kinase Inhibitors
Epidermal Growth Factor Receptor (EGFR)
Kinase/Phosphatase Biology
Intracellular Signaling
Protein Kinase