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TYRPHOSTIN B44

TYRPHOSTIN B44 Structure
CAS No.
133550-32-0
Chemical Name:
TYRPHOSTIN B44
Synonyms
AG 527;Zinc03871437;TYRPHOSTIN B44;TYRPHOSTIN AG 527;TRYPHOSTIN AG 527;TYRPHOSTIN B44(-);Reaxys ID: 4356230;ALPHA-CYANO-(-)-(R)-N-(ALPHA-PHENETHYL)-3,4-DIHYDROXYCINNAMIDE;(-)-(r)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide;(-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE
CBNumber:
CB8197102
Molecular Formula:
C18H16N2O3
Molecular Weight:
308.33
MOL File:
133550-32-0.mol
Modify Date:
2023/5/18 11:31:14
Request For Quotation

TYRPHOSTIN B44 Properties

Boiling point 603.0±55.0 °C(Predicted)
Density 1.299±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility DMSO or ethanol: soluble
form Yellow solid.
pka 8.81±0.10(Predicted)

SAFETY

Risk and Safety Statements

Safety Statements  22-24/25
WGK Germany  3

TYRPHOSTIN B44 Chemical Properties,Uses,Production

Uses

Tyrphostin B44, (-) enantiomer is a potent inhibitor of (EGFR) kinase.

Biological Activity

Potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC 50 = 0.4 μ M), more active than the (+) enantiomer ((S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylethyl)-2-propenamide ). Selective over ErbB2.

TYRPHOSTIN B44 Preparation Products And Raw materials

Raw materials

Preparation Products

TYRPHOSTIN B44 Suppliers

Global( 35)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Energy Chemical 021-58432009 400-005-6266 China 44843 58 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9707 58 Inquiry
Beijing Haite lesk Technology Co., Ltd 15210893940; 15116916250 China 7328 58 Inquiry
BOC Sciences 1-631-485-4226; 16314854226 United States 14059 65 Inquiry
WEITIXIHAUGONG 0371-53370800 18037197114 China 10002 58 Inquiry
EMD Biosciences, Inc. 858 450 5500 United States 6529 66 Inquiry
Fluorochem Ltd. +44 1457 868921 United Kingdom 6406 74 Inquiry
VWR International 800 932 5000 United Kingdom 6554 82 Inquiry
Spectrum Chemicals & Laboratory Products 310 516 8000 United States 6706 77 Inquiry
Supplier Advantage
Amadis Chemical Company Limited 58
Energy Chemical 58
Shanghai EFE Biological Technology Co., Ltd. 58
Beijing Haite lesk Technology Co., Ltd 58
BOC Sciences 65
WEITIXIHAUGONG 58
EMD Biosciences, Inc. 66
Fluorochem Ltd. 74
VWR International 82
Spectrum Chemicals & Laboratory Products 77

133550-32-0(TYRPHOSTIN B44)Related Search:

TYRPHOSTIN B44, (+) ENANTIOMER N1-ISOPROPYL-2-CYANOACETAMIDE D,L-N-(ALPHA-PHENYLETHYL) METHACRYLAMIDE AG 99 3-(1-PHENYLETHYLAMINO)PROPANENITRILE
TYRPHOSTIN B44 (R)-(+)-N-ALLYL-ALPHA-METHYLBENZYLAMINE& N-ISOPROPYLMETHACRYLAMIDE AG 490 BENZYL-((E)-3-PHENYL-ALLYL)-AMINE
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(R)-(E)-2-CYANO-3-(3',4'-DIHYDROXYPHENYL)-N-(1-PHENYLETHYL)-2-PROPENAMIDE (-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXY-BENZYLIDENECYANOACETAMIDE (-)-(R)-N-(ALPHA-METHYLBENZYL)-3,4-DIHYDROXYBENZYLIDINECYANOACETAMIDE TYRPHOSTIN AG 527 TYRPHOSTIN B44 TYRPHOSTIN B44(-) TRYPHOSTIN AG 527 AG 527 ALPHA-CYANO-(-)-(R)-N-(ALPHA-PHENETHYL)-3,4-DIHYDROXYCINNAMIDE (-)-(r)-n-(α-methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide Tyrphostin B44, (-)-(R)-N-(α-Methylbenzyl)-3,4-dihydroxybenzylidenecyanoacetamide Zinc03871437 (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]-2-propenamide Reaxys ID: 4356230 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1R)-1-phenylethyl]-, (2E)- 133550-32-0 BioChemical Cell Signaling and Neuroscience Cell Biology Receptor Tyrosine Kinase Inhibitors Epidermal Growth Factor Receptor (EGFR) Kinase/Phosphatase Biology Intracellular Signaling Protein Kinase