EC 3.4.22.1

CAS No.: 9047-22-7

Chemical Name:: EC 3.4.22.1

Synonyms: CATHEPSIN B;EC 3.4.22.1;Cathepsin II;units/mg protein;Native Human Cathepsin B;Native Bovine Cathepsin B;CATHEPSIN B, BOVINE SPLEEN;CATHEPSIN B1, BOVINE SPLEEN;CATHEPSIN B FROM HUMAN LIVER;CATHEPSIN B FROM BOVINE SPLEEN

CBNumber:: CB8206132

Molecular Formula:: NULL

Molecular Weight:: 0

MOL File:: Mol file

Modify Date:: 2024/7/2 8:55:18

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EC 3.4.22.1 Properties

storage temp.	-70°C
solubility	H2O: soluble1.0mg/mL, clear
form	lyophilized powder
color	White to off-white

SAFETY

Risk and Safety Statements

Hazard Codes	B
WGK Germany	3
RTECS	FI5725000
F	10-21

EC 3.4.22.1 price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	C6286	Cathepsin B from bovine spleen lyophilized powder, ≥10?units/mg protein	9047-22-7	10UNITS	₹17360.4	2022-06-14	Buy
Sigma-Aldrich(India)	C6286	Cathepsin B from bovine spleen lyophilized powder, ≥10?units/mg protein	9047-22-7	25UNITS	₹35753.1	2022-06-14	Buy
Sigma-Aldrich(India)	C8571	Cathepsin B from human liver buffered aqueous solution, ≥1,500?units/mg protein (E1%/280)	9047-22-7	25μG	₹41847	2022-06-14	Buy
Sigma-Aldrich(India)	C6286	Cathepsin B from bovine spleen lyophilized powder, ≥10?units/mg protein	9047-22-7	100UNITS	₹109002	2022-06-14	Buy
Sigma-Aldrich(India)	C0150	Cathepsin B from human placenta lyophilized powder, ≥5?units/mg protein	9047-22-7	2UNITS	₹7892.1	2022-06-14	Buy

Product number	Packaging	Price	Buy
C6286	10UNITS	₹17360.4	Buy
C6286	25UNITS	₹35753.1	Buy
C8571	25μG	₹41847	Buy
C6286	100UNITS	₹109002	Buy
C0150	2UNITS	₹7892.1	Buy

EC 3.4.22.1 Chemical Properties,Uses,Production

Uses

Cathepsin B from human liver has been used:

as a positive control in the screening Cathepsin B inhibitor assay
in wall extension (expansin activity) assay
in microinjection human foreskin fibroblasts to test its effect on apoptosis induction

General Description

Cathepsin B gene is mapped to human chromosome 8p23.1. It is a lysosomal cysteine with 252 amino acids distributed in two chains and is homologous to rat liver sequence. It has disc shaped structure with two domains namely the left-hand ′L′ domain at the amino terminal and right hand ′R′ domain at the carboxyl-terminal.

Purification Methods

Cathepsin B is purified by affinity chromatography on the semicarbazone of Gly-Phe-glycinal-linked to Sepharose 4B, with elution by 2,2'-dipyridyl disulfide [Rich et al. Biochem J 235 731 1986, Methods Enzymol 80 551 1981].

EC 3.4.22.1 Preparation Products And Raw materials

Raw materials

Preparation Products

EC 3.4.22.1 Suppliers

Global( 32)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Hubei Ipure Biology Co., Ltd	+8613367258412	China	10326	58	Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58	Inquiry
Shanghai Maclean Biochemical Technology Co., LTD	021-50706066 15221275939	China	29803	58	Inquiry
ACROBiosystems	18514007688	China	972	58	Inquiry
Creative Enzymes	1-516-855-7709	United States	6057	58	Inquiry
Shanghai Guchen Biotechnology Co., LTD	021-34675735 19147740836	China	9849	58	Inquiry
Shanghai Jizhi Biochemical Technology Co. Ltd.	400-400-400-9004166 18616739031	China	52712	58	Inquiry
Hubei Chenghai Chemical Co., Ltd	027-59220433 18327245847	China	9971	58	Inquiry
Hubei Wande Chemical Co., Ltd	027-59210159 15377098680	China	9976	58	Inquiry
Tianmen Hengchang Chemical Co., Ltd	027-59322316 15172518801	China	9910	58	Inquiry

Supplier	Advantage
Hubei Ipure Biology Co., Ltd	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Shanghai Maclean Biochemical Technology Co., LTD	58
ACROBiosystems	58
Creative Enzymes	58
Shanghai Guchen Biotechnology Co., LTD	58
Shanghai Jizhi Biochemical Technology Co. Ltd.	58
Hubei Chenghai Chemical Co., Ltd	58
Hubei Wande Chemical Co., Ltd	58
Tianmen Hengchang Chemical Co., Ltd	58

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CATHEPSIN B CATHEPSIN B1, BOVINE SPLEEN CATHEPSIN B, BOVINE SPLEEN EC 3.4.22.1 CATHEPSIN B FROM HUMAN LIVER CathepsinB from human placenta,CathepsinB1 CathepsinB from bovine spleen,Cathepsin B1 CATHEPSIN B FROM HUMAN PLACENTA CATHEPSIN B FROM BOVINE SPLEEN CathepsinB from human liver,CathepsinB1 Cathepsin II Cathepsin B from Human, recombinant Native Human Cathepsin B Native Bovine Cathepsin B units/mg protein 9047-22-7 Enzymes Proteins and Peptides Cathepsins and Granzymes Cell Signaling and Neuroscience Cell Biology Apoptosis and Cell Cycle Cancer Research Cancer Markers and Antibodies BioChemical