Bucladesine sodium
- CAS No.
- 16980-89-5
- Chemical Name:
- Bucladesine sodium
- Synonyms
- DC 2797;,5ÕDBcAMP-Na;N6-2ÕPrestwick_32;CAMP, DB-, NA;BUCLADESINE NA;dt5621sodiumsalt;DIB-3:5-CAMP, NA;bucladesinesodium
- CBNumber:
- CB8236166
- Molecular Formula:
- C18H25N5NaO8P
- Molecular Weight:
- 493.39
- MOL File:
- 16980-89-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/2/7 13:51:22
Melting point | >173°C (dec.) |
---|---|
storage temp. | -20°C |
solubility | H2O: 50 mg/mL |
form | powder |
color | white |
Merck | 14,1463 |
Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month. |
InChIKey | DBXVIQJWMFGXGO-AOTDUVMNNA-N |
SMILES | O([C@@H]1[C@]2([H])OP(O)(=O)OC[C@@]2([H])O[C@H]1N1C=NC2C(=NC=NC1=2)NC(=O)CCC)C(=O)CCC.[NaH] |&1:1,2,10,13,r| |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
Safety Statements | 24/25 |
WGK Germany | 2 |
RTECS | ES5055500 |
F | 10-21 |
HS Code | 29349990 |
Bucladesine sodium price More Price(15)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | D0627 | N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt ≥96% (HPLC), powder | 16980-89-5 | 25MG | ₹7609.98 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D0627 | N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt ≥96% (HPLC), powder | 16980-89-5 | 100MG | ₹18012.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D0627 | N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt ≥96% (HPLC), powder | 16980-89-5 | 250MG | ₹34499.28 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D0627 | N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt ≥96% (HPLC), powder | 16980-89-5 | 1G | ₹105576.23 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | D0627 | N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt ≥96% (HPLC), powder | 16980-89-5 | 5X1G | ₹345826.28 | 2022-06-14 | Buy |
Bucladesine sodium Chemical Properties,Uses,Production
Description
Bucladesine sodium is a derivative of cyclic-AMP with cardiac stimulant and peripheral vasodilatory properties. It is reported to be useful in cardiac insufficiency, especially after heart surgery.
Uses
Bucladesine sodium is an analog of cyclic AMP that stimulates cAMP-dependent protein kinase. It has vasodilator properties and is used as a cardiac stimulant.
Definition
ChEBI: Bucladesine sodium is a 3',5'-cyclic purine nucleotide.
Application
N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt has been used:
as a medium supplement for neural crest stem cells (NCSCs) differentiation
as a component of thawing medium for cryopreserved human iPSC (induced pluripotent stem cell)-derived neurons
in serum-free Dulbecco′s modified eagle′s medium (DMEM) to induce astrocyte differentiation
General Description
A cell-permeable cAMP analog that preferentially activates cAMP-dependent protein kinase (PKA). Causes an increase in the steady state level of parathyroid hormone-related peptide mRNA. Also acts as a Hh pathway antagonist. Shown to induce apoptosis in vascular smooth muscle cells.
Bucladesine sodium Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
Anand Agencies | 91-20-24454597 | Maharashtra, India | 2337 | 58 | Inquiry |
Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
Sisco Resech Laboratories Private Limited | +91-22-4268 5800 | Mumbai, India | 655 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
HangZhou RunYan Pharma Technology Co.,LTD. | +86-88660901 +86-18112526015 | China | 326 | 58 | Inquiry |
Hangzhou Meiya Pharmaceutical Co Ltd | +86-021-33686691 +8618001850931 | China | 58 | 58 | Inquiry |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5959 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |
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