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Bucladesine

Bucladesine Structure
CAS No.
362-74-3
Chemical Name:
Bucladesine
Synonyms
Bucladesin;BUCLADESINE;N-(9-beta-D-Ribofura;Cyclic AMP dibutyrate;Dibutyryl cyclic 3',5'-AMP;Dibutyryl 3',5'-Cyclic AMP;CalciuM Dibutyacyladenosine;3',5'-Cyclic AMP dibutyrate;Bucladesine (Dibutyryl-cAMP);Butyryladenosine Cyclophosphate
CBNumber:
CB42130314
Molecular Formula:
C18H24N5O8P
Molecular Weight:
469.39
MOL File:
362-74-3.mol
Modify Date:
2024/2/6 18:17:50

Bucladesine Properties

Density 1.72±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility DMSO; Methano
pka 0.82±0.60(Predicted)
form Solid
color White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H320-H335
Precautionary statements  P264-P270-P301+P312-P330

Bucladesine Chemical Properties,Uses,Production

Description

Bucladesine is a cyclic nucleotide derivative that mimics the action of endogenous CYCLIC AMP and is capable of permeating the cell membrane. It has vasodilator properties and is used as a cardiac stimulant. (From Merck Index, 11th ed)

Uses

Bucladesine is a cell permeable cAMP analog. The compound is used in a wide variety of research applications because it mimics cAMP and can induce normal physiological responses when added to cells in experimental conditions. cAMP is only able to elicit minimal responses in these situations. The neurite outgrowth instigated by bucladesine in cell cultures has been shown to be enhanced by nardosinone.

Definition

ChEBI: Bucladesine is a 3',5'-cyclic purine nucleotide that is the 2'-butanoate ester and 6-N-butanoyl derivative of 3',5'-cyclic AMP. It has a role as an agonist, a vasodilator agent and a cardiotonic drug. It is a butyrate ester, a 3',5'-cyclic purine nucleotide and a member of butanamides. It is functionally related to a 3',5'-cyclic AMP.

Bucladesine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 88)Suppliers
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BUCLADESINE n-6,o-2'-dibutyryl adenosine cyclic 3':5'-monophosphate n-(9-beta-d-ribofuranosyl-9h-furin-6-yl)-butyramide cyclic 3',5'-(hydrogen phosphate) 2'-butyrate 3',5'-Cyclic AMP dibutyrate Cyclic AMP dibutyrate Dibutyryl 3',5'-Cyclic AMP Dibutyryl cyclic 3',5'-AMP N-(9-beta-D-Ribofura CalciuM Dibutyacyladenosine Dibutyryladenosine cyclic 3',5'-monophosphate Calciuml Dibutyryladenosine Cyclophosphate Butyryladenosine Cyclophosphate N-(9-beta-D-Ribofuranosyl-9H-furin-6-yl)-butyramide cyclic 3',5'-(hydrogen phosphate) 2'-butyrate USP/EP/BP Bucladesine (Dibutyryl-cAMP) Bucladesin Bucladesine calcium salt (DB-cAMP.Ca) 362-74-3