Oxiracetam
- CAS No.
- 62613-82-5
- Chemical Name:
- Oxiracetam
- Synonyms
- 4-hydroxy-2-oxo-1-pyrrolidineacetamid;2-(4-Hydroxy-2-oxopyrrolidin-1-yl)acetamide;ct-848;isf2522;Neurome;Olaxitam;Neuractiv;CGP 21690;oxiraceta;xiracetam
- CBNumber:
- CB3328242
- Molecular Formula:
- C6H10N2O3
- Molecular Weight:
- 158.16
- MOL File:
- 62613-82-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/16 10:38:43
| Melting point | 165-168 °C |
|---|---|
| Boiling point | 494.6±40.0 °C(Predicted) |
| Density | 1.416 |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
| pka | 13.76±0.20(Predicted) |
| form | Solid |
| color | White to Off-White |
| Merck | 14,6942 |
| InChI | InChI=1S/C6H10N2O3/c7-5(10)3-8-2-4(9)1-6(8)11/h4,9H,1-3H2,(H2,7,10) |
| InChIKey | IHLAQQPQKRMGSS-UHFFFAOYSA-N |
| SMILES | N1(CC(N)=O)CC(O)CC1=O |
| CAS DataBase Reference | 62613-82-5(CAS DataBase Reference) |
Oxiracetam price More Price(2)
Oxiracetam Chemical Properties,Uses,Production
Description
Oxiracetam is a structural analogue of piracetam. This compound has enhancing effects on vigilance and memory. In comparison with piracetam, oxiracetam exhibits greater improvement in memory (Itil et al., 1986) and has been used extensively for the treatment of dementia, including AD, VaD, MID (Baumel et al., 1989; Dysken et al., 1989), and mixed forms. Green et al. (1992) failed to demonstrate a difference from placebo in AD patients. In contrast, Maina et al. (1989) studied 289 patients with MID in a double-blind placebo-controlled trial and after 12 weeks of treatment found that oxiracetam reduced behavioural symptoms.
Chemical Properties
Whie Solid
Uses
Oxiracetam is a 4-hydroxy analog of piracetam with psychostimulant activity, reportedly useful in relieving the symptoms of cerebral insufficiency in the elderly.
Purification Methods
This nootropic (Alzheimer) drug is purified by recrystallisation from MeOH or aqueous Me2CO and dried in vacuo. [NMR, IR: Pifferi & Pinza Farmaco Ed Sci 32 602 1977, Banfi et al. Farmaco Ed Sci 39 16 1984, Gouilaev & Senning Brain Research Rev 19 180 1994.]
Oxiracetam Preparation Products And Raw materials
Raw materials
1of2
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