[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid

CAS No.: 378247-75-7

Chemical Name:: [7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid

Synonyms: Fmoc-7-aminocoumarin-4-acetic acid;Pyridine,2,3,6-trichloro-8-nitro-;N-Fmoc-Aminocoumarin-4-acetic acid;7-N-Fmoc-aminocoumarin-4-acetic acid;7-(Fmoc-amino)-2-oxo-2H-1-benzopyran-4-acetic acid;7-(9-Fluorenylmethyloxycarbonylamino)-coumarin-4-acetic acid;[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid;7-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-2H-1-benzopyran-4-acetic acid;2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)aceticaci;2H-1-Benzopyran-4-acetic acid, 7-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-

CBNumber:: CB82489625

Molecular Formula:: C26H19NO6

Molecular Weight:: 441.43

MOL File:: 378247-75-7.mol

Modify Date:: 2023/7/14 17:43:39

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[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Properties

Melting point	273-276 °C
Boiling point	660.5±55.0 °C(Predicted)
Density	1.418±0.06 g/cm3(Predicted)
storage temp.	Store at +2°C to +8°C.
pka	4.23±0.10(Predicted)

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	8.52309	Fmoc-ACA-OH Novabiochem?	378247-75-7	250MG	₹9480	2022-06-14	Buy
Sigma-Aldrich(India)	8.52309	Fmoc-ACA-OH Novabiochem?	378247-75-7	1G	₹28210	2022-06-14	Buy

Product number	Packaging	Price	Buy
8.52309	250MG	₹9480	Buy
8.52309	1G	₹28210	Buy

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Chemical Properties,Uses,Production

General Description

Fmoc-ACA-OH is a useful tool for the SPPS of AMC fluorogenic protease substrates. Fmoc-ACA-OH [1] must be first loaded onto a Wang-type resin. Any unreacted linker hydroxyls must be capped using acetic anhydride. Following Fmoc removal, the first amino acid should be coupled withy HATU/collidine [2]. Insertion of ACA into the middle of a peptide provides fluorogenic substrates for endopeptidases [3]. Treatment of the ACC peptide obtained after TFA cleavage with aqueous base causes facile decarboxylation and formation of the AMC peptide.

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Preparation Products And Raw materials

Raw materials

ETHYL (3-HYDROXYPHENYL)CARBAMATE 7-Amino-4-carboxymethylcoumarin 3-Aminophenol 9-Fluorenylmethyl chloroformate

Preparation Products

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid Suppliers

Global( 41)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
SL Drugs and Pharmaceuticals Pvt. Ltd.	+91 (40) 6661-1133	New Delhi, India	2688	50	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
Otto Chemie Pvt. Ltd.	+91 9820041841	Mumbai, India	5873	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30253	58	Inquiry
Nextpeptide Inc	+86-0571-81612335 +8613336028439	China	19915	58	Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58	Inquiry
Amadis Chemical Company Limited	571-89925085	China	131980	58	Inquiry
Wuxi Kehua Biological Technology Co., Ltd.	0510-0510-86838766	China	3839	58	Inquiry
Shanghai Kaiwei Chemical Technology Co., Ltd.	021-58461859 15821823057	China	49323	58	Inquiry
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 18112977050	China	16687	50	Inquiry

Supplier	Advantage
SL Drugs and Pharmaceuticals Pvt. Ltd.	50
A.J Chemicals	58
Otto Chemie Pvt. Ltd.	58
Career Henan Chemica Co	58
Nextpeptide Inc	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Amadis Chemical Company Limited	58
Wuxi Kehua Biological Technology Co., Ltd.	58
Shanghai Kaiwei Chemical Technology Co., Ltd.	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	50

[7-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-oxo-2H-chromen-4-yl]-aceticacid 2-(7-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-2-oxo-2H-chroMen-4-yl)acetic acid 7-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo-2H-1-benzopyran-4-acetic acid 7-N-Fmoc-aminocoumarin-4-acetic acid 2-[7-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-2-oxo-1-benzopyran-4-yl]acetic acid 2H-1-Benzopyran-4-acetic acid, 7-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-oxo- N-Fmoc-Aminocoumarin-4-acetic acid Fmoc-7-aminocoumarin-4-acetic acid 2-(7-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-oxo-2H-chromen-4-yl)aceticaci Pyridine,2,3,6-trichloro-8-nitro- 7-(Fmoc-amino)-2-oxo-2H-1-benzopyran-4-acetic acid 7-(9-Fluorenylmethyloxycarbonylamino)-coumarin-4-acetic acid 378247-75-7