2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline

2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline Structure
CAS No.
77094-11-2
Chemical Name:
2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline
Synonyms
MEIQ;4-MEIQ;5-f]quinoline;4-dimethyl-3H-imidazo[4;3,4-dimethyl-2-imidazo[4,5-f]quinolinamine;3,4-DIMETHYLIMIDAZO(4,5-F)QUINOLIN-2-AMINE;2-amino-3,4-dimethylimidazo(4,5-f)quinoline;3,4-dimethyl-3h-imidazo(4,5-f)quinolin-2-amine;5-f)quinoline,2-amino-3,4-dimethyl-3h-imidazo(;3H-Imidazo[4,5-f]quinolin-2-amine, 3,4-dimethyl-
CBNumber:
CB8256591
Molecular Formula:
C12H12N4
Molecular Weight:
212.25
MOL File:
77094-11-2.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:16

2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline Properties

Melting point 291-293
Boiling point 342.09°C (rough estimate)
Density 1.2046 (rough estimate)
refractive index 1.5000 (estimate)
storage temp. Refrigerator
solubility Methanol (Slightly)
pka 6.22±0.40(Predicted)
form Solid
color Yellow
Stability Hygroscopic
IARC 2B (Vol. Sup 7, 56) 1993
EPA Substance Registry System 2-Amino-3,4-dimethylimidazo(4,5-f)quinoline (77094-11-2)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Warning
Hazard statements  H341-H351
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
Hazard Codes  T
Hazard Note  Toxic
HS Code  2933998090

2-Amino-3,4-dimethyl-3H-imidazo[4,5-f]quinoline Chemical Properties,Uses,Production

Chemical Properties

Yellow Crystalline Solid

Uses

Mutagenic heterocyclic amines in cooked food

Production Methods

Heterocyclic amines are formed by condensation of creatinine with amino acids during heating or cooking of meat (beef, pork, chicken, and fish). They have also been detected in processed food flavorings, beer, wine, and cigarette smoke. 2-Amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ) and related heterocyclic amines are produced in small quantities for research purposes. Exposure to MeIQ and related heterocyclic amines occurs primarily through the consumption of cooked meats.Concentrations of heterocyclic amines in meats varied under different cooking conditions (375). The highest concentrations of MeIQ were detected in grilled fish, which appear to be the major dietary source of heterocyclic amines in Japanese. U.S. surveys of dietary intakes of heterocyclic amines in cooked foods have also been reported. Occupational exposure to heterocyclic amines may occur by inhalation of aerosolized particles formed during the cooking process.

General Description

Pale orange crystalline solid or light yellow powder.

Air & Water Reactions

2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE is sensitive to light and air. Slightly water soluble .

Reactivity Profile

2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE is rapidly degraded by dilute hypochlorite.

Health Hazard

ACUTE/CHRONIC HAZARDS: 2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE may emit potentially toxic fumes when involved in a fire.

Fire Hazard

Flash point data for 2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE are not available; however, 2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx,.

Carcinogenicity

MeIQ is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals and supporting genotoxicity data.

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2-amino-3,4-dimethylimidazo(4,5-f)quinoline 3,4-dimethyl-3h-imidazo(4,5-f)quinolin-2-amine 2-AMINO-3,4-DIMETHYL-3H-IMIDAZO [4,5-F]QUINOLINE 5-f)quinoline,2-amino-3,4-dimethyl-3h-imidazo( MEIQ MelQ (2-Amino-3,4-dimethylimidazo[4,5f]quinoline 3,4-DIMETHYLIMIDAZO(4,5-F)QUINOLIN-2-AMINE 4-MEIQ 3,4-dimethyl-2-imidazo[4,5-f]quinolinamine 3H-Imidazo[4,5-f]quinolin-2-amine, 3,4-dimethyl- 4-dimethyl-3H-imidazo[4 5-f]quinoline 77094-11-2 Detergents Mutagenesis Research Chemicals