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4-Piperidinone

4-Piperidinone Structure
CAS No.
41661-47-6
Chemical Name:
4-Piperidinone
Synonyms
Piperidin-4-one;4-PIPERIDONE;4-Oxopiperidine;LUBE-013;4-piperidin;γ-Piperidone;1-yl)acetyl)-;4-Piperidinon;γ-Piperidinone;4-piperidinone
CBNumber:
CB8260941
Molecular Formula:
C5H9NO
Molecular Weight:
99.13
MOL File:
41661-47-6.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

4-Piperidinone Properties

Boiling point 175.1±15.0 °C(Predicted)
Density 1.001±0.06 g/cm3(Predicted)
pka 8.95±0.20(Predicted)
form solid
color yellow
CAS DataBase Reference 41661-47-6(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P261-P280
Risk Statements  11-20/21/22
Safety Statements  16-26-36/37/39
RIDADR  1993
HazardClass  IRRITANT
HS Code  2914390090

4-Piperidinone Chemical Properties,Uses,Production

Description

4-Piperidinone is a derivative of piperidine with the molecular formula C5H9NO. 4-Piperidone is used as an intermediate in the manufacture of chemicals and pharmaceutical drugs.
Piperidones are a class of chemical compounds sharing the piperidone skeleton. A classic named reaction for the synthesis of piperidones is the Petrenko-Kritschenko piperidone synthesis which involves combining an alkyl-1,3-acetonedicarboxylate with benzaldehyde and an amine. This multicomponent reaction is related to the Hantzsch pyridine synthesis.

Uses

4-Piperidone monohydrate hydrochloride was used in the generation of compound libraries based on sub-reactions of an Ugi multicomponent reaction (MCR).

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AKOS BBS-00004234 1-((6-chloro-2,3-dihydro-2-(4-methoxyphenyl)-3-oxo-1h-isoindol-1-yl)acetyl)-4-piperidinon 4-Piperidinon 4-Piperidone(Hclform) 4-Piperidone ,98% 4-piperidin 1-yl)acetyl)- 3-dihydro-2-(4-methoxyphenyl)-3-oxo-1h-isoindol-1-yl)acetyl)-1-((6-chloro- 4-piperidinone γ-Piperidinone γ-Piperidone LUBE-013 Irinotecan Impurity 34 Irinotecan Hydroxyl Acid 16 Piperidin-4-one hydrochL Loratadine Impurity 22 HCl (Mixture of Ketone and Ketone Hydrate) 4-PIPERIDINONE HCL MONOHYDRATE Irinotecan Impurity 16 HCl 4-PIPERIDONE 4-Oxopiperidine Piperidin-4-one 4-Piperidinone (9CI, ACI) Loratadine Impurity 22 HCl Loratadine Impurity 63 HCl 41661-47-6 C5H9NO Miscellaneous