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Ebastine

Ebastine Structure
CAS No.
90729-43-4
Chemical Name:
Ebastine
Synonyms
EBASTIN;EBASTEL;LAS-90;Ebasine;Estivan;EVASTEL;KESTINE;ebastina;RP 64305;EBASTINE
CBNumber:
CB8271800
Molecular Formula:
C32H39NO2
Molecular Weight:
469.66
MOL File:
90729-43-4.mol
MSDS File:
SDS
Modify Date:
2024/3/15 13:40:56

Ebastine Properties

Melting point 80-82°C
Boiling point 596.3±50.0 °C(Predicted)
Density 1.09±0.1 g/cm3(Predicted)
storage temp. 2-8°C
solubility Slightly soluble in chloroform, methanol.
form solid
pka 8.19±0.10(Predicted)
color white
Merck 14,3484
CAS DataBase Reference 90729-43-4(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H303
Precautionary statements  P270-P301+P312-P403-P501c
WGK Germany  3
RTECS  EL8140000
HS Code  2933.39.9200

Ebastine price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) E9531 Ebastine ≥98% (HPLC), solid 90729-43-4 10MG ₹24865.03 2022-06-14 Buy
Sigma-Aldrich(India) E9531 Ebastine ≥98% (HPLC), solid 90729-43-4 50MG ₹104353 2022-06-14 Buy
TCI Chemicals (India) E0925 Ebastine 90729-43-4 1G ₹8100 2022-05-26 Buy
TCI Chemicals (India) E0925 Ebastine 90729-43-4 5G ₹19800 2022-05-26 Buy
Product number Packaging Price Buy
E9531 10MG ₹24865.03 Buy
E9531 50MG ₹104353 Buy
E0925 1G ₹8100 Buy
E0925 5G ₹19800 Buy

Ebastine Chemical Properties,Uses,Production

Description

Ebastine is a new once-daily histamine Hl-receptor antagonist with no sedative effects or autonomic impairment at therapeutic doses. It is reported to be effective in the treatment of hay fever, perennial rhinitis, and uticaria. Ebastine's antihistamine activity is attributed to its carboxylic acid metabolite carebastine.

Chemical Properties

White to Off-White Powder

Uses

Ebastine is a second-generation H1 receptor antagonist that is indicated mainly for allergic rhinitis and chronic idiopathic urticaria. It is available in 10 and 20 mg tablets and as fast-dissolving tablets, as well as in pediatric syrup. It has a recommended flexible daily dose of 10 or 20 mg, depending on disease severity.

General Description

Ebastine is metabolised by cytochrome P450 3A (CYP3A4) to carebastine. It is used to treat allergic rhinitis and chronic idiopathic urticaria.

Global( 391)Suppliers
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Anphar Laboratories Pvt Ltd +91-9018670066 +91-9018670066 Himachal Pradesh, India 17 58 Inquiry
R L Fine Chem Pvt. Ltd +91-8042488999 +91-8042488999 Karnataka, India 74 58 Inquiry
Rivashaa Agrotech Biopharma Pvt. Ltd. +91-26463395 +91-7926462688 Gujarat, India 1615 58 Inquiry
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Fine Chemicals & Scientific Co. 91-11-23580683 Delhi, India 69 58 Inquiry
Chempro Pharma Pvt. Ltd. 91-22-40945230 Maharashtra, India 170 58 Inquiry

Ebastine Spectrum

4'-(1,1-Dimethylethyl)-γ-[4-(diphenylmethoxy)piperidin-1-yl]butyrophenone 4'-tert-Butyl-γ-[4-(diphenylmethoxy)piperidino]butyrophenone Ebastel-OD LAS-90 IMp. A (EP): DiphenylMethanol (Benzhydrol) Ebastine Impurity 1-butanone,1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidiny 4’-tert-butyl-4-(4-(diphenylmethoxy)piperidino)butyrophenone 4-diphenylmethoxy-1-(3-(4-tert-butylbenzoyl)propyl)piperidine ebastina Ebasine EBASTINE, REFERENCE SPECTRUM EP STANDARD EBASTINE, IMPURITY C4-(DIPHENYLMETHOXY)PIPERIDINE EP STANDARD EBASTINE, MM STANDARD EBASTINE, IMPURITY D1-[4-(1,1-DIMETHYLETHYL)PHENYL]-4-(4-HYDROXYPIPERIDIN-1-YL)BUTAN-1-ONE EP STANDARD 1-[4-(1,1-Dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]-1-butanone Estivan LAS-W 090 RP 64305 LAS-W-090:Bastd 4-(4-benzhydryloxy-1-piperidyl)-1-(4-tert-butylphenyl)butan-1-one EBASTINE EVASTEL KESTINE 1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-buta Ebastine CRS Ebastine> 1-Butanone, 1-[4-(1,1-dimethylethyl)phenyl]-4-[4-(diphenylmethoxy)-1-piperidinyl]- Ebastine USP/EP/BP Ebastine (LAS-W 090 Ebastine D6 EbastineQ: What is Ebastine Q: What is the CAS Number of Ebastine Q: What is the storage condition of Ebastine Q: What are the applications of Ebastine Ebastine (1231207) EBASTEL EBASTIN EBATINE IP/ BP 4-[4-(Benzhydryloxy)-1-piperidyl]-1-[4-(tert-butyl)phenyl]-1-butanone Ibastatin Ebasidine 90729-43-4 90729-49-4 C32H39NO2 Inhibitors Active Pharmaceutical Ingredients Intermediates & Fine Chemicals Pharmaceuticals 90729-43-4