DFMO

DFMO Structure
CAS No.
70052-12-9
Chemical Name:
DFMO
Synonyms
DIFLUOROMETHYLORNITHINE;DFMO;RFI 71782;Ccris 3295;Brn 2250529;EFLORNITINE;DL-EFLORNITHINE;H-DL-(F2ME)ORN-OH;α-Difluoromethylornitine;α-difluoromethylornithine
CBNumber:
CB8373227
Molecular Formula:
C6H12F2N2O2
Molecular Weight:
182.17
MOL File:
70052-12-9.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:19

DFMO Properties

Melting point 138 °C
Boiling point 347.0±42.0 °C(Predicted)
Density 1.1800 (estimate)
storage temp. Store at 0°C
solubility H2O: >10 mg/mL, soluble
pka 1.22±0.44(Predicted)
form solid
color white

SAFETY

Risk and Safety Statements

WGK Germany  3

DFMO price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) D193 DL-α-Difluoromethylornithine hydrochloride hydrate solid, ≥97% (NMR) 70052-12-9 25MG ₹19885.53 2022-06-14 Buy
Sigma-Aldrich(India) D193 DL-α-Difluoromethylornithine hydrochloride hydrate solid, ≥97% (NMR) 70052-12-9 100MG ₹64592.78 2022-06-14 Buy
Product number Packaging Price Buy
D193 25MG ₹19885.53 Buy
D193 100MG ₹64592.78 Buy

DFMO Chemical Properties,Uses,Production

Chemical Properties

Off-white powder

Uses

DL-α-Difluoromethylornithine hydrochloride hydrate has been used to reduce the effects of arginine on cell proliferation. It has also been used to investigate the effect of bisphenol A (BPA) on the migration of an established ovine trophectoderm (oTr1) cell line.

General Description

Difluoromethylornithine is a?fluorinated ornithine analog, which acts as a rate-limiting enzyme of polyamine biosynthesis. It is used to treat female facial hirsutism and human African trypanosomiasis. Difluoromethylornithine functions as a chemopreventive and chemotherapeutic agent against neuroblastoma and colorectal cancer. It exhibits cytostatic?effects on mammalian cells and tissues.

Biological Activity

Inhibitor of ornithine decarboxylase that inhibits polyamine biosynthesis. Displays antiapoptotic, antiangiogenic and antiparasitic activity.

DFMO Preparation Products And Raw materials

Raw materials

Preparation Products

DFMO Suppliers

Global( 66)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43348 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131980 58 Inquiry
Shanghai Weiwei Biological Technology Co., Ltd. 021-55669583 18616258598 CHINA 4398 58 Inquiry
96020-91-6 (Mono-hydrochloride, monohydrate) alpha,delta-Diamino-alpha-(difluoromethyl)valeric acid Brn 2250529 Ccris 3295 DL-2-(Difluoromethyl)-ornithinehydrochloride DL-α-Difluoromethylornithine hydrochloride hydrate,2-(Difluoromethyl)ornithine hydrochloride hydrate, DFMO hydrochloride hydrate, Eflornithine hydrochloride hydrate DIFLUOROMETHYLORNITHINE(RG) α-Difluoromethyl-DL-ornithine DFMO hydrochloride hydrate DL-α-Difluoromethylornithine hydrochloride hydrate RFI 71782 DL-2-(DIFLUORO-METHYL)-ORNITHINE HCL DL-(α-difluoromethyl)Orn-OH α-Difluoromethyl-DL-ornithine≥ 98% (NMR) 2-(difluoromethyl)-ornithin alpha-difluoromethylornithine alpha-difluromethylornithine ALPHA-DIFLUORO-ME-DL-ORNITHINE ALPHA-DIFLUOROMETHYL-DL-ORNITHINE 2-(Difluoromethyl)ornithine hydrate hydrochloride, DFMO hydrate hydrochloride DL-α-Difluoromethylornithine hydrate hydrochloride 2-(Difluoromethyl)-2,5-diaminovaleric acid α-Difluoromethylornitine DL-α-Difluoromethylornithine hydrochloride H-DL-(ALPHA-DIFLUOROMETHYL)ORN-OH H-DL-(F2ME)ORN-OH H-ALPHA-DIFLUORO-ME-DL-ORN-OH EFLORNITINE DL-ALPHA-DIFLUOROMETHYLORNITHINE DFMO DL-ALPHA-DIFLUOROMETHYLORNITHINE HYDROCHLORIDE HYDRATE Ornithine, 2-(difluoromethyl)- Eflornithine base (racemic) DL-EFLORNITHINE EflornithineQ: What is Eflornithine Q: What is the CAS Number of Eflornithine Q: What is the storage condition of Eflornithine Q: What are the applications of Eflornithine α-difluoromethylornithine DIFLUOROMETHYLORNITHINE MFCD00221766 Eflornithine RMI71782|||DFMO|||α-difluoromethylornithine|||MDL71782 70052-12-9 C6H12N2O2F2 Angiogenesis Inhibitors Angiogenesis BioChemical Cancer Research facial hair remover