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Teprenone

Teprenone Structure
CAS No.
6809-52-5
Chemical Name:
Teprenone
Synonyms
geranylgeranylacetone;Selbex;eprenone;TEPRENONE;Tepronone;Teprenone RS;UNII-S8S8451A4O;Teprenone, >=98%;Tetraprenylacetone;All trans-Teprenone
CBNumber:
CB8386175
Molecular Formula:
C23H38O
Molecular Weight:
330.55
MOL File:
6809-52-5.mol
MSDS File:
SDS
Modify Date:
2024/3/28 17:11:29

Teprenone Properties

Boiling point bp0.01 155-160°
Density d420.5 0.9081
refractive index nD20 1.4947
storage temp. -20°C
solubility DMSO: >5mg/mL
form liquid
color clear
Merck 14,9228
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChIKey SBOCYPUKNYDTSX-DMLVRTFPSA-N
LogP 8.200 (est)
CAS DataBase Reference 6809-52-5(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3
RTECS  RA5391300
HS Code  2914.19.0000
NFPA 704
3
2 0

Teprenone price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) G5048 Geranylgeranylacetone 6809-52-5 10MG ₹8746.6 2022-06-14 Buy
Sigma-Aldrich(India) G5048 Geranylgeranylacetone 6809-52-5 50MG ₹35062.18 2022-06-14 Buy
TCI Chemicals (India) T2701 Teprenone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers] min. 95.0 %(total of isomer) 6809-52-5 1G ₹9100 2022-05-26 Buy
TCI Chemicals (India) T2701 Teprenone [mixture of (5E,9E,13E)- and (5Z,9E,13E)- isomers] min. 95.0 %(total of isomer) 6809-52-5 5G ₹14500 2022-05-26 Buy
Product number Packaging Price Buy
G5048 10MG ₹8746.6 Buy
G5048 50MG ₹35062.18 Buy
T2701 1G ₹9100 Buy
T2701 5G ₹14500 Buy

Teprenone Chemical Properties,Uses,Production

Description

Teprenone (geranylgeranylacetone) is an antiulcer agent whose synthesis was inspired by the gastric protecting properties of Coenzyme Q10. Teprenone is reported to act via enhancement of gastric mucosal glycoprotein secretion.

Chemical Properties

Yellow Oil

Uses

An anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.

Definition

ChEBI: A terpene ketone in which a (9E,13E)-geranylgernayl group is bonded to one of the alpha-methyls of acetone (it is a mixture of 5E- and 5Z-geoisomers in a 3:2 ratio).

Global( 189)Suppliers
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A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
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