Elastase
- CAS No.
- 39445-21-1
- Chemical Name:
- Elastase
- Synonyms
- Elastase;Elastasee;EC 3.4.21.37;EC 3.4.21.36;LYSOSOMAL ELASTASE;Elastase, Purified;ELASTASE, LEUKOCYTE;Elastase USP/EP/BP;PANCREATOPEPTIDASE E;Elastase (pig pancreas)
- CBNumber:
- CB8394260
- Molecular Formula:
- NULL
- Molecular Weight:
- 0
- MOL File:
- Mol file
- MSDS File:
- SDS
- Modify Date:
- 2023/9/7 18:57:57
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H334-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | B,Xn |
| Risk Statements | 36/37/38-42 |
| Safety Statements | 23-24-26-36/37-22 |
| WGK Germany | 3 |
| F | 3-10 |
Elastase price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | E7885 | Elastase from porcine pancreas lyophilized powder, suitable for cell culture | 39445-21-1 | 1MG | ₹7636.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E1250 | Elastase from porcine pancreas Type I, ≥4.0?units/mg protein | 39445-21-1 | 10MG | ₹5516.7 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E7885 | Elastase from porcine pancreas lyophilized powder, suitable for cell culture | 39445-21-1 | 5MG | ₹22488.6 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E1250 | Elastase from porcine pancreas Type I, ≥4.0?units/mg protein | 39445-21-1 | 25MG | ₹10334.1 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | E7885 | Elastase from porcine pancreas lyophilized powder, suitable for cell culture | 39445-21-1 | 20MG | ₹62337.6 | 2022-06-14 | Buy |
Elastase Chemical Properties,Uses,Production
Uses
Elastase is used in combination with other proteases for protein analysis by mass spectrometry. Elastase, is used in tissue dissociation because elastin is found in highest concentrations in the elastic fibers of connective tissues, elastase is frequently used to dissociate tissues that contain extensive intercellular fiber networks. It is usually used with other enzymes such as collagenase, trypsin, and chymotrypsin, membrane protein solubilization, protein sequence studies.
General Description
Elastase is a single polypeptide chain of 240 amino acid residues and contains four disulfide bridges. The molecular mass is approximately 25.9kDa. The enzyme is synthesized as an inactive zymogen, proelastase, which is converted to the active form by limited proteolysis at the N-terminal by trypsin.
Biochem/physiol Actions
Elastase is a single polypeptide chain of 240 amino acid residues and contains four disulfide bridges. The molecular mass is approximately 25.9 kDa. The enzyme is synthesized as an inactive zymogen, proelastase, which is converted to the active form by limited proteolysis at the N-terminal by trypsin. It is a serine protease with broad specificity. It cleaves protein at the carboxyl side of small hydrophobic amino acids such as Ile, Gly, Ala, Ser, Val, and Leu. The enzyme also hydrolyzes amides and esters such as N-Benzoyl-L-alanine methyl ester. The pH optimum is found to be 8.0-8.5. It does not require any activator, but it is inhibited by diisopropyl fluorophosphate, phenylmethanesulfonyl fluoride, α2-macroglobulin, α1-antitrypsin, sulfonyl fluorides and p-dinitrophenyl diethylphosphate and high salt concentrations. It is extensively used in tissue and cell dissociation procedures. Elastase is effective in the isolation of Type II lung cells.
Elastase Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 6010 | 58 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12459 | 58 | Inquiry |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | China | 10326 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
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