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4-Aminobenzohydrazide

4-Aminobenzohydrazide Structure
CAS No.
5351-17-7
Chemical Name:
4-Aminobenzohydrazide
Synonyms
4-POBN;4NPhCON2;aminostimil;WLN: ZNUYQR DZ;ambenhydrazide;Amben hydrazide;TIMTEC-BB SBB007555;P-AMINOBENZHYDRAZIDE;4-AMINOBENZHYDRAZIDE;N,4-Diaminobenzamide
CBNumber:
CB8434256
Molecular Formula:
C7H9N3O
Molecular Weight:
151.17
MOL File:
5351-17-7.mol
MSDS File:
SDS
Modify Date:
2023/5/18 11:31:16

4-Aminobenzohydrazide Properties

Melting point 225-227 °C (lit.)
Boiling point 273.17°C (rough estimate)
Density 1.2100 (rough estimate)
refractive index 1.5860 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMF: 10 mg/ml; DMSO: 14 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
form Crystals or Powder
pka 13.05±0.10(Predicted)
color White or beige
Water Solubility Soluble in DMSO (10 mg/ml), dilute acids, and water (partly miscible).
BRN 639053
CAS DataBase Reference 5351-17-7(CAS DataBase Reference)
NIST Chemistry Reference Benzoic acid, 4-amino-, hydrazide(5351-17-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  DG2580000
HazardClass  IRRITANT
HS Code  29280000
NFPA 704
0
1 0

4-Aminobenzohydrazide price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A41909 4-Aminobenzoic hydrazide 95% 5351-17-7 10G ₹2792.85 2022-06-14 Buy
Sigma-Aldrich(India) 475944 Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem The Myeloperoxidase Inhibitor-I, also referenced under CAS 5351-17-7, controls the biological activity of Myeloperoxidase. This small molecule/inhibit 5351-17-7 1G ₹9380 2022-06-14 Buy
ALFA India ALF-A10963-22 4-Aminobenzhydrazide, 98% 5351-17-7 100g ₹4836 2022-05-26 Buy
ALFA India ALF-A10963-14 4-Aminobenzhydrazide, 98% 5351-17-7 25g ₹3194 2022-05-26 Buy
TCI Chemicals (India) A1211 4-Aminobenzohydrazide 5351-17-7 25G ₹8200 2022-05-26 Buy
Product number Packaging Price Buy
A41909 10G ₹2792.85 Buy
475944 1G ₹9380 Buy
ALF-A10963-22 100g ₹4836 Buy
ALF-A10963-14 25g ₹3194 Buy
A1211 25G ₹8200 Buy

4-Aminobenzohydrazide Chemical Properties,Uses,Production

Description

4-Aminobenzoic acid hydrazide (4-ABAH) is an irreversible inhibitor of myeloperoxidase (MPO; IC50 = 0.3 μM). It reduces the production of hypochlorous acid (HOCl) induced by opsonized zymosan or phorbol 12-myristate 13-acetate (PMA; ) in isolated human neutrophils with IC50 values of 16 and 2.2 μM, respectively. 4-ABAH inhibits PMA-induced formation of neutrophil extracellular traps (NETs) in the same cells. It reduces infarct volume and the severity of neurological deficits, as well as increases survival, in a mouse model of cerebral ischemia induced by transient middle cerebral artery occlusion (MCAO) when administered at a dose of 40 mg/kg twice per day.

Chemical Properties

White or beige crystals or powder

Uses

4-Aminobenzhydrazide has an important role in the peroxidation activity of MPO. It is also used in enzyme preparations and in cell cultures.

4-Aminobenzohydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

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4-AMINOBENZHYDRAZIDE 4-AMINOBENZOHYDRAZIDE 4-AMINOBENZOYLHYDRAZIDE 4-AMINO-BENZOIC ACID HYDRAZIDE 4-AMINOBENZOIC HYDRAZIDE TIMTEC-BB SBB007555 P-AMINOBENZOYL HYDRAZIDE P-AMINOBENZOHYDRAZIDE P-AMINOBENZHYDRAZIDE 4-amino-benzoicacihydrazide 4-Aminobenzoylhydrazine Amben hydrazide 4-Aminobenzoic acid hydrazide~(4-Aminobenzoyl)hydrazine 4-Aminobenzhydrazide, 98+% benzoic acid, 4-amino-, hydrazide AMino benzoyl hydrazine (4-AMinobenzoyl)hydrazide, 95% 5GR 4-AMinobenzoic hydrazide 95% 4NPhCON2 Benzoic acid, 4-amino-, hydrazide (9CI) WLN: ZNUYQR DZ N,4-Diaminobenzamide (4-Aminobenzoyl)hydrazide,95% ambenhydrazide aminostimil Benzoic acid, p-amino-, hydrazide p-Amino benzoyl hydrazine p-Aminobenzoic hydrazide p-amino-benzoicacihydrazide p-aminobenzoylhydrazine para-Aminobenzhydrazide LABOTEST-BB LT00010042 MYELOPEROXIDASE INHIBITOR-I P-AMINOBENZOIC ACID HYDRAZIDE Myeloperoxidase Inhibitor 4-Aminobenzohydrazide > 4-POBN Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem 5351-17-7 H2NC6H4CONHNH2 C7H9ON3 Building Blocks Carbonyl Compounds Organic Building Blocks Hydrazides Carbonyl Compounds Hydrazides Organic Building Blocks Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes Amines