4-Aminobenzohydrazide
![4-Aminobenzohydrazide Structure](CAS/GIF/5351-17-7.gif)
- CAS No.
- 5351-17-7
- Chemical Name:
- 4-Aminobenzohydrazide
- Synonyms
- 4-POBN;4NPhCON2;aminostimil;WLN: ZNUYQR DZ;ambenhydrazide;Amben hydrazide;TIMTEC-BB SBB007555;P-AMINOBENZHYDRAZIDE;4-AMINOBENZHYDRAZIDE;N,4-Diaminobenzamide
- CBNumber:
- CB8434256
- Molecular Formula:
- C7H9N3O
- Molecular Weight:
- 151.17
- MOL File:
- 5351-17-7.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/18 11:31:16
Melting point | 225-227 °C (lit.) |
---|---|
Boiling point | 273.17°C (rough estimate) |
Density | 1.2100 (rough estimate) |
refractive index | 1.5860 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMF: 10 mg/ml; DMSO: 14 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml |
form | Crystals or Powder |
pka | 13.05±0.10(Predicted) |
color | White or beige |
Water Solubility | Soluble in DMSO (10 mg/ml), dilute acids, and water (partly miscible). |
BRN | 639053 |
CAS DataBase Reference | 5351-17-7(CAS DataBase Reference) |
NIST Chemistry Reference | Benzoic acid, 4-amino-, hydrazide(5351-17-7) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | DG2580000 | |||||||||
HazardClass | IRRITANT | |||||||||
HS Code | 29280000 | |||||||||
NFPA 704 |
|
4-Aminobenzohydrazide price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | A41909 | 4-Aminobenzoic hydrazide 95% | 5351-17-7 | 10G | ₹2792.85 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 475944 | Myeloperoxidase Inhibitor-I - CAS 5351-17-7 - Calbiochem The Myeloperoxidase Inhibitor-I, also referenced under CAS 5351-17-7, controls the biological activity of Myeloperoxidase. This small molecule/inhibit | 5351-17-7 | 1G | ₹9380 | 2022-06-14 | Buy |
ALFA India | ALF-A10963-22 | 4-Aminobenzhydrazide, 98% | 5351-17-7 | 100g | ₹4836 | 2022-05-26 | Buy |
ALFA India | ALF-A10963-14 | 4-Aminobenzhydrazide, 98% | 5351-17-7 | 25g | ₹3194 | 2022-05-26 | Buy |
TCI Chemicals (India) | A1211 | 4-Aminobenzohydrazide | 5351-17-7 | 25G | ₹8200 | 2022-05-26 | Buy |
4-Aminobenzohydrazide Chemical Properties,Uses,Production
Description
4-Aminobenzoic acid hydrazide (4-ABAH) is an irreversible inhibitor of myeloperoxidase (MPO; IC50 = 0.3 μM). It reduces the production of hypochlorous acid (HOCl) induced by opsonized zymosan or phorbol 12-myristate 13-acetate (PMA; ) in isolated human neutrophils with IC50 values of 16 and 2.2 μM, respectively. 4-ABAH inhibits PMA-induced formation of neutrophil extracellular traps (NETs) in the same cells. It reduces infarct volume and the severity of neurological deficits, as well as increases survival, in a mouse model of cerebral ischemia induced by transient middle cerebral artery occlusion (MCAO) when administered at a dose of 40 mg/kg twice per day.
Chemical Properties
White or beige crystals or powder
Uses
4-Aminobenzhydrazide has an important role in the peroxidation activity of MPO. It is also used in enzyme preparations and in cell cultures.
4-Aminobenzohydrazide Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
SREE SYNERIC LAB | +91-91-6383636810 +91-9884742764 | Tamil Nadu, India | 465 | 58 | Inquiry |
NSC Organics | 08069013898Ext 371 | Hyderabad, India | 166 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29898 | 58 | Inquiry |
Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | China | 2169 | 58 | Inquiry |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
Supplier | Advantage |
---|---|
SREE SYNERIC LAB | 58 |
NSC Organics | 58 |
CHEMSWORTH | 30 |
A.J Chemicals | 58 |
TCI Chemicals (India) Pvt. Ltd. | 58 |
Alfa Aesar | 58 |
career henan chemical co | 58 |
Changzhou Ditong Chemical Co.,Ltd | 58 |
Chongqing Chemdad Co., Ltd | 58 |
CONIER CHEM AND PHARMA LIMITED | 58 |
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