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PP1

CAS No.: 172889-26-8

Chemical Name:: PP1

Synonyms: PP1;PPEN;EI 275;CS-716;PP1 Base;AGL 1872;PP1 USP/EP/BP;PP1, Free Base;PP1 (AGL 1872);AGL 1872,EI 275

CBNumber:: CB8472133

Molecular Formula:: C16H19N5

Molecular Weight:: 281.36

MOL File:: 172889-26-8.mol

MSDS File:: SDS

Modify Date:: 2023/6/30 15:45:59

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PP1 Properties

Melting point	205-207°C
storage temp.	room temp
solubility	DMSO: >20mg/mL
form	powder
color	white to off-white
Stability	Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P280-P305+P351+P338

Hazard Codes

Risk Statements

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

HS Code

2933599590

NFPA 704

	0
2		0

PP1 price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	P0040	PP1 ≥98% (HPLC)	172889-26-8	5MG	₹21390.2	2022-06-14	Buy
Sigma-Aldrich(India)	P0040	PP1 ≥98% (HPLC)	172889-26-8	25MG	₹86112.88	2022-06-14	Buy

Product number	Packaging	Price	Buy
P0040	5MG	₹21390.2	Buy
P0040	25MG	₹86112.88	Buy

PP1 Chemical Properties,Uses,Production

Chemical Properties

Off-White to Grey Solid

Uses

PP1 has been used as:

an inhibitor of sarcoma (Src) family kinases (SFK) like hematopoietic cell kinase (hck) and fyn
a selective Src tyrosine kinase inhibitor in hippocampal neuronal cultures to test its effect on neurite growth
a Src-kinase blocker to test its effect on brimonidine (BMD)-induced phosphorylation in extracellular signal-activated kinases(ERK1/2)

Biological Activity

Potent inhibitor of Src-family tyrosine kinases. Inhibits p56 lck and p59 fynT (IC 50 values are 5 and 6 nM respectively). Displays > 8000-fold selectivity over ZAP-70 and JAK2. Also moderately inhibits p38, CSK, PDGF receptors, RET-derived oncoproteins, c-Kit and Bcr-Abl.

PP1 Preparation Products And Raw materials

Raw materials

Preparation Products

PP1 Suppliers

Global( 165)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32760	60	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	China	26368	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	China	9991	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	China	11681	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry

Supplier	Advantage
A.J Chemicals	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
Coresyn Pharmatech Co., Ltd.	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Aladdin Scientific	58

PP1 Spectrum

PP1(172889-26-8)MS

172889-26-8(PP1)Related Search:

PP2 USP/EP/BP PP242 PP-360 PP 148 PP1

PP PP2B PP3 PP211 Cypermethrin

EC 3.1.1.1 PP (31-36) MURINE CYTOMEGALOVIRUS PP 89 (170-174),MURINE CMV PP 89 (170-174) MURINE CYTOMEGALOVIRUS PP 89 (168-176),MURINE CMV PP 89 (168-176) (L)-HIV-TAT48-57-PP-JBD20

PP-3 PP2A PP1 ANALOG II,1 NM-PP1

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PP1 Base EI 275 1-(1,1-Dimethylethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine 4-Amino-1-tert-butyl-3-(4-methylphenyl)pyrazolo[3,4-d]pyrimidine AGL 1872 4-AMINO-5-(4-METHYLPHENYL)-7-(T-BUTYL)PYRAZOLO[3,4-D]PYRIMIDINE 4-AMINO-5-(4-METHYLPHENYL)-7-(TERT-BUTYL)PYRAZOLO[3,4-D]PYRIMIDINE 1-(TERT-BUTYL)-3-(4-METHYLPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE 1-(TERT-BUTYL)-3-(4-METHYLPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 1-(1,1-dimethylethyl)-3-(4-methylphenyl)- AGL 1872,EI 275 4-Amino-5-(methylphenyl)-7-(t-butyl)pyrazolo-(3,4-d)pyrimidine 1-tert-butyl-3-p-tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine PP1 (Src Inhibitor) 7-tert-Butyl-5-p-tolyl-6,7-dihydro-5H-pyrazolo[3,4-d]pyrimidin-4-amine PP 1 (enzyme inhibitor) Src Inhibitor, PP1 1-(1,1-DIMETHYLETHYL)-1-(4-METHYLPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE PP1 PP1; PP 1; PP-1. CS-716 PP1, Free Base 1-tert-Butyl-3-p-tolyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine PP1 (AGL 1872) PP1;PP 1;PP-1;AGL 1872;EI 275 PP1 USP/EP/BP 1-(tert-Butyl)-3-(p-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine[AGL 1872 P-436 Poly(1-pentene) Poly(1-propyl-1,2-ethanediyl) Poly(1-propylethylene) PPEN PP1,AGL1872,EI275,EI-275,PP-1,Inhibitor,AGL-1872,PP 1,Src,inhibit,Apoptosis 172889-26-8 C16H19N5 多肽抗原小鼠抗人和大、小鼠磷酸酯酶-1 多克隆抗体 Inhibitors Heterocyclic Compounds Bases & Related Reagent Heterocycles Nucleotides Protein Kinase Inhibitors and Activators Protein Kinase