Tocainide hydrochloride
- CAS No.
- 35891-93-1
- Chemical Name:
- Tocainide hydrochloride
- Synonyms
- Xylotocan;TOCAINIDE HCL;Unii-2K7I38ckn5;tonocardhydrochloride;tocainide hydrochloride;TOCAINIDE HYDROCHLORIDE (125 MG);Tocainide hydrochloride USP/EP/BP;Tocainide Hydrochloride (1667552);2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride;2-amino-n-(2,6-dimethylphenyl)-propanamidmonohydrochloride
- CBNumber:
- CB8500546
- Molecular Formula:
- C11H17ClN2O
- Molecular Weight:
- 228.71848
- MOL File:
- 35891-93-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/4/23 13:52:06
Tocainide hydrochloride Chemical Properties,Uses,Production
Uses
Tonocard(AstraZeneca).
General Description
Tocainide hydrochloride,2-amino-2＇ ,6 ＇-propionoxyxylidide hydrochloride (Tonocard)(pKa 7.7), is an analog of lidocaine. It is orally active and haselectrophysiological properties like those of lidocaine. Totalbody clearance of tocainide hydrochloride is only166 mL/min, suggesting that hepatic clearance is not large.Because of low hepatic clearance, the hepatic extraction ratiomust be small; therefore, tocainide hydrochloride is unlikelyto be subject to a substantial first-pass effect. The drug differsfrom lidocaine, in that it lacks two ethyl groups, which providestocainide hydrochloride some protection from first-passhepatic elimination after oral ingestion. Tocainide hydrochlorideis hydrolyzed in a manner similar to that of lidocaine.None of its metabolites is active.
Clinical Use
Tocainide hydrochloride is classed as a IB antiarrhythmicagent and used orally to prevent or treat ventricular ectopyand tachycardia. The drug is given in 400- to 600-mgdoses every 8 hours.
Tocainide hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | China | 9030 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| Shanxi New Baoyuan Pharmaceutical Co., Ltd. | 0352-7606558 | China | 10 | 58 | Inquiry |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | China | 9874 | 58 | Inquiry |
| Hunan Zhangjiajie Hengkang Biological Pharmaceutical Co., LTD | 0731-85561023 18973109536 | China | 393 | 58 | Inquiry |
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