Tocainide hydrochloride
Tocainide hydrochloride
- CAS:
- 35891-93-1
- MF:
- C11H17ClN2O
- MW:
- 228.71848
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Properties
- Melting point:
- 244-245°C
- storage temp.
- -20°C Freezer
- solubility
- Methanol (Slightly), Water (Slightly)
- form
- Solid
- color
- Off-White
Safety Information
- HS Code
- 2924296000
Use
Tocainide hydrochloride,2-amino-2' ,6 '-propionoxyxylidide hydrochloride (Tonocard)(pKa 7.7), is an analog of lidocaine. It is orally active and haselectrophysiological properties like those of lidocaine. Totalbody clearance of tocainide hydrochloride is only166 mL/min, suggesting that hepatic clearance is not large.Because of low hepatic clearance, the hepatic extraction ratiomust be small; therefore, tocainide hydrochloride is unlikelyto be subject to a substantial first-pass effect. The drug differsfrom lidocaine, in that it lacks two ethyl groups, which providestocainide hydrochloride some protection from first-passhepatic elimination after oral ingestion. Tocainide hydrochlorideis hydrolyzed in a manner similar to that of lidocaine.None of its metabolites is active.
0 India supplier list of "Tocainide hydrochloride"
- Product Name:TocainideHydrochloride(1667552)
- Products Intro:Brand:pharmaffiliates | Product Number:PAUSP1667552
- Company Type: Trader
- Country/Region: Haryana,INDIA