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Antazoline

Antazoline Structure
CAS No.
91-75-8
Chemical Name:
Antazoline
Synonyms
5512-M;Avissul;Azalone;Antastan;Antasten;Antistin;Antazolin;Antistine;Chemiopen;Histostab
CBNumber:
CB8667315
Molecular Formula:
C17H19N3
Molecular Weight:
265.35
MOL File:
91-75-8.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:37

Antazoline Properties

Melting point 120-122°
Boiling point 398.57°C (rough estimate)
Density 0.9786 (rough estimate)
refractive index 1.6080 (estimate)
pka pKa 6.65(H2O t = 25 I = 0.05) (Uncertain)
form A solid
color White to off-white
Water Solubility 663.4mg/L(30 ºC)
CAS DataBase Reference 91-75-8(CAS DataBase Reference)
NIST Chemistry Reference Antazoline(91-75-8)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H335-H302-H315-H319-H312
Precautionary statements  P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Toxicity LD50 oral in mouse: 398mg/kg

Antazoline Chemical Properties,Uses,Production

Chemical Properties

White, odorless crystalline powder with bitter taste. Sparingly soluble in alcohol and water; practically insoluble in benzene and ether.

Uses

Antihistaminic.

Definition

ChEBI: A member of the class of imidazolines that is 2-aminomethyl-2-imidazoline in which the exocyclic amino hydrogens are replaced by benzyl and phenyl groups. Antazoline is only found in individuals that have taken the drug.

Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. An eye irritant. When heated to decomposition it emits toxic fumes of NOx.

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1H-Imidazole-2-methanamine, 4,5-dihydro-N-phenyl-N-(phenylmethyl)- 2-(N-Phenyl-N-benzylaminomethyl)imidazoline 2-[(N-Benzylanilino)methyl]-2-imidazol 2-[(N-Benzylanilino)methyl]-2-imidazoline 2-Imidazoline, 2-[(N-benzylanilino)methyl]- 2-Phenyl-benzyl-amino-methylimidazolin 4,5-Dihydro-N-phenyl-N-phenylmethyl-1H-imidazole-2-methanamine 5512-M Allergan A Analergine Antastan Antasten Antazolin Antihistal Antistin Antistine Archisulfa Avissul Azalone Ben-a-hist n-benzyl-n-(4,5-dihydro-1h-imidazol-2-ylmethyl)aniline Chemiopen Demosulfan Histostab Imidamine Orosulfan Phenazoline Risulfasens Sulfaperine Sulfatreis albalon-a 2-(N-PHENYL-N-BENZYL-AMINOMETHYL)-IMIDAZOLINE 0.5 H2SO4 BENZYL-(4,5-DIHYDRO-1H-IMIDAZOL-2-YLMETHYL)-PHENYL-AMINE 0.5 H2SO4 ANTAZOLINE ANTAZOLINE 0.5 H2SO4 N-benzyl-N-(2-imidazolin-2-ylmethyl)aniline Antazoline (base and/or unspecified salts) N-benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)benzenamine Antazoline & Antazoline Hydrochloride Antazoline Hydrochloride Ph. Eur. Antazoline USP/EP/BP nervous system,Inhibitor,H1 receptor antagonist,inhibit,Phenazoline,Antazoline,Histamine Receptor 91-75-8 C17H20N3Cl Imidazoline agonist; more potent than efaroxan in inducing insulin release from beta cells; H1 histamine receptor antagonist.