1-Naphthyl isothiocyanate
![1-Naphthyl isothiocyanate Structure](CAS/GIF/551-06-4.gif)
- CAS No.
- 551-06-4
- Chemical Name:
- 1-Naphthyl isothiocyanate
- Synonyms
- ANI;ANIT;Kesscocide;1-Naphthyl senfoel;Naphthyl mustard oil;1-Naftylisothiokyanat;Naphthyl isothiocyanat;1-NAPTHYL ISOTHIOCYANATE;1-Naphtyl isothiocyanate;1-NAPHTHYL ISOTHIOCYANATE
- CBNumber:
- CB8696418
- Molecular Formula:
- C11H7NS
- Molecular Weight:
- 185.24
- MOL File:
- 551-06-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/4 17:34:39
Melting point | 55.5-57 °C(lit.) |
---|---|
Boiling point | 190 °C(Press: 20 Torr) |
Density | 1.1142 (rough estimate) |
refractive index | 1.5500 (estimate) |
storage temp. | 2-8°C |
form | Fine Crystalline Powder |
color | Yellow |
Water Solubility | insoluble |
Sensitive | Moisture Sensitive |
Merck | 14,6411 |
BRN | 637868 |
Stability | Stable, but moisture sensitive. Incompatible with strong oxidizing agents. |
CAS DataBase Reference | 551-06-4(CAS DataBase Reference) |
NIST Chemistry Reference | Naphthalene, 1-isothiocyanato-(551-06-4) |
EPA Substance Registry System | 1-Naphthylisothiocyanate (551-06-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS06,GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H301-H312+H332-H315-H319-H334-H335 | |||||||||
Precautionary statements | P261-P280-P301+P310-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
Hazard Codes | T | |||||||||
Risk Statements | 20/21-25-36/37/38-42-23/24/25 | |||||||||
Safety Statements | 22-26-36/37-45-24/25 | |||||||||
RIDADR | UN 2811 6.1/PG 3 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | NX9100000 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | II | |||||||||
HS Code | 29309090 | |||||||||
NFPA 704 |
|
1-Naphthyl isothiocyanate price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | N4525 | 1-Naphthyl isothiocyanate 95% | 551-06-4 | 10G | ₹8053.8 | 2022-06-14 | Buy |
Sigma-Aldrich | 18951 | 1-Naphthyl isothiocyanate for HPLC derivatization, LiChropur?, ≥98.5% (HPLC and GC) | 551-06-4 | 1G | ₹4892.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 18951 | 1-Naphthyl isothiocyanate for HPLC derivatization, LiChropur?, ≥98.5% (HPLC and GC) | 551-06-4 | 1G | ₹4892.9 | 2022-06-14 | Buy |
TCI Chemicals (India) | I0190 | 1-Naphthyl Isothiocyanate | 551-06-4 | 5G | ₹7200 | 2022-05-26 | Buy |
ALFA India | ALF-L12418-09 | 1-Naphthyl isothiocyanate, 98% | 551-06-4 | 10g | ₹10731 | 2022-05-26 | Buy |
1-Naphthyl isothiocyanate Chemical Properties,Uses,Production
Description
1-Napthylisothiocyanate is a toxic chemical that has been used to create experimental cholestasis in rodents. Laboratory studies have also shown that 1-napthylisothiocyanate can act as a chemoprotectant in rodents challenged with a tumorinducing agent such as phorbol-12 myristate 13-acetate.
Chemical Properties
white crystalline powder
Uses
1-Naphthyl isothiocyanate is a tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bile duct hyperplasia and biliary cirrhosis chronically, with changes in hepatocyte function.
General Description
Odorless white needles or powder. Tasteless.
Air & Water Reactions
1-Naphthyl isothiocyanate is moisture sensitive. . Undergoes slow hydrolysis. Insoluble in water.
Reactivity Profile
Isocyanates and thioisocyanates, such as 1-Naphthyl isothiocyanate, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].
Fire Hazard
Flash point data for 1-Naphthyl isothiocyanate is not available, but 1-Naphthyl isothiocyanate is probably combustible.
Environmental Fate
Naphthylisothiocyanate is moisture sensitive and insoluble in water. The hydrolysis rate is slow.
Purification Methods
Crystallise the isothiocyanate from hexane (1g in 9 mL). It forms white needles and is soluble in most organic solvents but is insoluble in H2O. It is absorbed through the skin and may cause dermatitis. [Cymmerman-Craig et al. Org Synth Coll Vol IV 700 1963, Beilstein 12 H 1244, 12 III 2948.]
1-Naphthyl isothiocyanate Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | China | 2995 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29826 | 58 | Inquiry |
551-06-4(1-Naphthyl isothiocyanate)Related Search:
1of4
chevron_right