Hinokitiol
- CAS No.
- 499-44-5
- Chemical Name:
- Hinokitiol
- Synonyms
- 2,4,6-Cycloheptatrien-1-one, 2-hydroxy-4-(1-methylethyl)-;β-thujaplicin;Hinokitol;BETA-THUJAPLICIN;BETA-THUJAPLICINE;2-HYDROXY-4-ISOPROPYL-2,4,6-CYCLOHEPTATRIENE;2-HYDROXY-4-ISOPROPYLCYCLOHEPTA-2,4,6-TRIEN-1-ONE;HINOKITIOL;B-THUJAPLICIN;Hinokitiol>
- CBNumber:
- CB8714323
- Molecular Formula:
- C10H12O2
- Molecular Weight:
- 164.2
- MOL File:
- 499-44-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/14 18:30:21
| Melting point | 50-52 °C(lit.) |
|---|---|
| Boiling point | 140 °C10 mm Hg(lit.) |
| Density | 1.0041 (rough estimate) |
| refractive index | 1.5190 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). |
| form | solid |
| pka | 7.06±0.30(Predicted) |
| color | White |
| Odor | at 100.00 %. phenolic woody mossy |
| Odor Type | woody |
| Merck | 14,9390 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 4 months. |
| LogP | 1.137 (est) |
| CAS DataBase Reference | 499-44-5(CAS DataBase Reference) |
| NIST Chemistry Reference | 2,4,6-Cycloheptatrien-1-one, 2-hydroxy-4-(1-methylethyl)-(499-44-5) |
| EPA Substance Registry System | 2,4,6-Cycloheptatrien-1-one, 2-hydroxy-4-(1-methylethyl)- (499-44-5) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS06,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300+H310+H330-H315-H319-H410 | |||||||||
| Precautionary statements | P501-P273-P260-P270-P262-P271-P264-P280-P284-P391-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P310+P330-P302+P352+P310-P304+P340+P310-P403+P233-P405 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | GU4200000 | |||||||||
| HS Code | 2914290090 | |||||||||
| NFPA 704 |
|
Hinokitiol price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 469521 | β-Thujaplicin 99% | 499-44-5 | 5G | ₹9937.35 | 2022-06-14 | Buy |
| TCI Chemicals (India) | H0142 | Hinokitiol min. 99.0 % | 499-44-5 | 1G | ₹2400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | H0142 | Hinokitiol min. 99.0 % | 499-44-5 | 5G | ₹7300 | 2022-05-26 | Buy |
Hinokitiol Chemical Properties,Uses,Production
Description
Hinokitiol (β-thujaplicin) is a natural monoterpenoid found in the wood of trees in the family Cupressaceae. It is a tropolone derivative and one of the thujaplicins.Hinokitiol is used in oral and skin care products,and is a food additive used in Japan.
Uses
Hinokitiol is a natural monoterpenoid found in the wood of trees in the family Cupressaceae. It is a tropolone derivative and one of the thujaplicins. Hinokitiol has inhibitory effects on Chlamydia trachomatis and may be clinically useful as a topical drug.
Definition
ChEBI: A monoterpenoid that is cyclohepta-2,4,6-trien-1-one substituted by a hydroxy group at position 2 and an isopropyl group at position 4. Isolated from Thuja plicata and Chamaecyparis obtusa, it exhibits antimicrobial activities.
Anticancer Research
Studied in xenograft tumors such lung adenocarcinoma cell, EGFR-TKI-resistantlines PC9-IR and H1975 in which the growth inhibition was observed, a novel antitumormechanism was hypothesized. In summary, the hinokitiol can induce DNAdamage and autophagy (Rodrigues et al. 2015).
Hinokitiol Preparation Products And Raw materials
Raw materials
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Global( 272)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Musks & Fragrance | +91-22-2624 9902 / 2624 4121 /2 670 3348 | New Delhi, India | 124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Kowa India Pvt., Ltd. | 91-22-28524680 | Maharashtra, India | 54 | 58 | Inquiry |
| Akshaya Laboratories Pvt. Ltd | -64642624 | Hyderabad, India | 125 | 58 | Inquiry |
| Kowa India Private Limited | 08048372776Ext 229 | Mumbai, India | 8 | 58 | Inquiry |
| Shandong Natural Micron Pharm Tech Co.,LTD | +86-18653895227 | China | 94 | 58 | Inquiry |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | China | 2255 | 58 | Inquiry |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 | China | 2788 | 58 | Inquiry |
499-44-5(Hinokitiol)Related Search:
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HINOKITIOL
B-THUJAPLICIN
2-HYDROXY-4-ISOPROPYL-2,4,6-CYCLOHEPTATRIEN-1-ONE
2-hydroxy-6-isopropyl-cyclohepta-2,4,6-trien-1-one
2-hydroxy-6-propan-2-yl-cyclohepta-2,4,6-trien-1-one
2-hydroxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one
THUJAPLICIN, BETA- (RG)
2-Hydroxy-4-isopropylcyclohepta-2,4,6-trien-1-one
beta-Thujaplicine
THUJAPLICIN, BETA-(HINOKITIOL)(P)
2-hydroxy-4-isopropylcyclohepta-2,4,6-trienone
Hinokitiol
2-Hydroxy-4-isopropyl-cyclohepta-2,4,6-trien-1-one
beta-Thujaplicin 99%
2-hydroxy-4-(1-methylethyl)-2,4,6-cycloheptatrien-1-one
2,4,6-Cycloheptatrien-1-one, 2-hydroxy-4-isopropyl-
6-cycloheptatrien-1-one,2-hydroxy-4-(1-methylethyl)-4
6-cycloheptatrien-1-one,2-hydroxy-4-isopropyl-4
beta-Isopropyltropolon
beta-Isopropyltropolone
Thujaplicin, beta
Tropolone, 4-isopropyl-
4-ISOPROPYLTROPOLONE
2-hydroxy-4-isopropyl-2,4,6-cyclohepta-2,4,6-trien-1-one
Isopropyltropolone
4-Isopropyl-2-hydroxy-2,4,6-cycloheptatrien-1-one
β-Thujaplicine
2-Hydroxy-4-isopropyl-2,4,6-cycloheptatrien-1-one, Hinokitiol
2-HYDROXY-4-(PROPAN-2-YL)CYCLOHEPTA-2,4,6-TRIEN-1-ONE
Hinokitiol Hinokitiol
Hinokitiol>
BETA-THUJAPLICIN
BETA-THUJAPLICINE
2-HYDROXY-4-ISOPROPYLCYCLOHEPTA-2,4,6-TRIEN-1-ONE
2-HYDROXY-4-ISOPROPYL-2,4,6-CYCLOHEPTATRIENE
Hinokitol
2,4,6-Cycloheptatrien-1-one, 2-hydroxy-4-(1-methylethyl)-
β-thujaplicin
4-Vinylbenzyl chloride 1592-20-7
4-Isopropyltropolone|||β-thujaplicin
499-44-5
499-44-4
Tropolones & Azulenes
Tropolones
Carbonyl Compounds
C10
Building Blocks
Ketones
Organic Building Blocks
Tropolones & Azulenes
Tropolones
499-44-5