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CARNOSOL

CARNOSOL Structure
CAS No.
5957-80-2
Chemical Name:
CARNOSOL
Synonyms
carnol;CARNOSOL;D-α-Alanine;CARNOSOL(RG);CARNOSOL USP/EP/BP;Carnosol, froM RoseMarinus officinalis;Carnosol, 98%, from Rosemarinus officinalis;1,3,4,9,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE;1,3,4,9,10,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE;1,2,3,4,4A,9,10,10AS-OCTAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISOPROPYL-9S, 4AR (EPOXYMETHANO)PHENANTHREN-12-ONE
CBNumber:
CB8736565
Molecular Formula:
C20H26O4
Molecular Weight:
330.42
MOL File:
5957-80-2.mol
MSDS File:
SDS
Modify Date:
2024/7/2 8:55:37
Request For Quotation

CARNOSOL Properties

Melting point 240～242℃
Boiling point 524.8±50.0 °C(Predicted)
Density 1.26±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility DMSO:66.0(Max Conc. mg/mL);199.74(Max Conc. mM)
pka 8.91±0.40(Predicted)
form Solid
color White
LogP 2.832 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H317
Precautionary statements  P280-P302+P352
Safety Statements  24/25
WGK Germany  3
HS Code  29322090

CARNOSOL price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 49702 Carnosol analytical standard 5957-80-2 10MG ₹52079.08 2022-06-14 Buy
Product number Packaging Price Buy
49702 10MG ₹52079.08 Buy

CARNOSOL Chemical Properties,Uses,Production

Description

Carnosol is a phenol that has been found in rosemary (R. officinalis) and has diverse biological activities. It decreases nitric oxide (NO) production in mouse peritoneal exudate macrophages when used at concentrations ranging from 6 to 25 μM. Carnosol scavenges peroxyl and hydroxyl radicals and inhibits lipid peroxidation in cell-free assays. It inhibits 5-lipoxygenase (5-LO; IC50 = 0.1 μM for the recombinant human enzyme) and the synthesis of leukotrienes in human polymorphonuclear leukocytes (PMNs; IC50 = 7 μM). In vivo, carnosol (200 mg/kg) reduces mammary DNA adduct formation and tumorigenesis in a rat model of DMBA-induced mammary tumorigenesis.

Chemical Properties

White powder

Uses

Carnosol is a phytopolyphenol found in Rosemary that functions as an antioxidant, antimicrobial, & anticarcinogen.

Cytotoxicity

IC50 (μg/mL): 65 (HL-60), 58 (K562), 50(Hep G2), 48 (MCF-7), 53 (MOLT-4)(Farimani et al. 2012)
IC50 (μg/mL): 61.46 (AGS) (Areche et al.2009)
IC50 (μg/mL): 2 (P388) (Aoyagi et al.2006)
IC50 (μg/mL): 1.19 (A2780), 3.30(SW1573), 8.59 (WiDr), 7.93 (T-47D),1.29 (HBL-100) (Guerrero et al. 2006).

CARNOSOL Preparation Products And Raw materials

Raw materials

Preparation Products

EPIROSMANOL Rosmanol

CARNOSOL Suppliers

Global( 199)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
BINBO BIOLOGICAL CO.,LTD +8618629063126 China 346 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29898 58 Inquiry
Chengdu GLP biotechnology Co Ltd 028-87075086 13350802083 CHINA 1824 58 Inquiry
Chengdu Biopurify Phytochemicals Ltd. +86-28-82633860 +86-18080483897 China 3424 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Neostar United (Changzhou) Industrial Co., Ltd. +86-519-519-85557386 China 11616 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418671 China 34571 58 Inquiry
ANHUI WITOP BIOTECH CO., LTD +8615255079626 China 23556 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
A.J Chemicals 58
BINBO BIOLOGICAL CO.,LTD 58
career henan chemical co 58
Chengdu GLP biotechnology Co Ltd 58
Chengdu Biopurify Phytochemicals Ltd. 58
Chongqing Chemdad Co., Ltd 58
Neostar United (Changzhou) Industrial Co., Ltd. 58
Hefei TNJ Chemical Industry Co.,Ltd. 58
ANHUI WITOP BIOTECH CO., LTD 58

CARNOSOL Spectrum

CARNOSOL(5957-80-2)1HNMR

5957-80-2(CARNOSOL)Related Search:

CARNOSOL Carnosic acid 1-PHENYL-1-CYCLOHEXANECARBOXYLIC ACID cyclomenol 1-(4-Methylphenyl)-1-cyclohexanecarboxylic acid
2 [PARA ISOPROPYL PHENYL] PROPIONALDEHYDE 2-CYCLOHEXYL-5-METHYLPHENOL ethyl 2-(4-ethylphenyl)acetate pisiferic acid CARNOSOL(NOW AVAILABLE IN GRAM SIZES)(P),CARNOSOL(P)
Carnosol, Rosmarinus officinalis tetrahydro-3-pentyl-2H-pyran-2-one 4-(1-METHYLETHYL)-BENZENEACETIC ACID METHYL ESTER ethyl 4-isopropylphenylacetate (1-phenylcyclohexane)methanol
DEHYDROABIETINE 1-Phenylcyclohexane-1-carbaldehyde 3-ISOPROPYL-6-METHYLCATECHOL
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1,3,4,9,10,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE 1,3,4,9,10AS-HEXAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISO-PROPYL-2H-9S,4AR-(EPOXYMETHANO)PHENANTHREN-12-ONE 1,2,3,4,4A,9,10,10AS-OCTAHYDRO-5,6-DIHYDROXY-1,1-DIMETHYL-7-ISOPROPYL-9S, 4AR (EPOXYMETHANO)PHENANTHREN-12-ONE CARNOSOL(RG) CARNOSOL Carnosol, froM RoseMarinus officinalis Carnosol, 98%, from Rosemarinus officinalis 2H-9,4a-(Epoxymethano)phenanthren-12-one, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR,9S,10aS)- CARNOSOL USP/EP/BP (4aR,9S,10aS)-5,6-Dihydroxy-7-isopropyl-1,1-dimethyl-2,3,4,9,10,10a-hexahydro-1H-9,4a-(epoxymethano)phenanthren-12-one D-α-Alanine carnol 5957-80-2 chemical reagent pharmaceutical intermediate Miscellaneous Natural Products Antioxidant Biochemicals Found in Plants Nutrition Research phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract