12-Crown-4
- CAS No.
- 294-93-9
- Chemical Name:
- 12-Crown-4
- Synonyms
- Crown;1,4,7,10-TETRAOXACYCLODODECANE;12-CROWN 4-ETHER;Eoct;12C4;12 C 4;12-C-4;12-CROWN-4;12-Crown-4,97%;LITHIUM IONOPHORE V
- CBNumber:
- CB8752442
- Molecular Formula:
- C8H16O4
- Molecular Weight:
- 176.21
- MOL File:
- 294-93-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/12/18 14:15:32
| Melting point | 16 °C (lit.) |
|---|---|
| Boiling point | 61-70 °C/0.5 mmHg (lit.) |
| Density | 1.089 g/mL at 25 °C (lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | Liquid After Melting |
| Specific Gravity | 1.115 (20℃) |
| color | Clear colorless to slightly yellow |
| Water Solubility | MISCIBLE |
| Sensitive | Air Sensitive |
| BRN | 1363064 |
| CAS DataBase Reference | 294-93-9(CAS DataBase Reference) |
| NIST Chemistry Reference | 12-Crown-4(294-93-9) |
| EPA Substance Registry System | 1,4,7,10-Tetraoxacyclododecane (294-93-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H330 | |||||||||
| Precautionary statements | P304+P340+P310 | |||||||||
| Hazard Codes | T+,Xn,Xi | |||||||||
| Risk Statements | 26-36/37/38-20/21/22 | |||||||||
| Safety Statements | 28-36/37-45-36-26 | |||||||||
| RIDADR | UN 2810 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | XF0550000 | |||||||||
| F | 3-9-23 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29329995 | |||||||||
| Toxicity | LD50 oral in rat: 2830mg/kg | |||||||||
| NFPA 704 |
|
12-Crown-4 price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 194905 | 12-Crown-4 98% | 294-93-9 | 1G | ₹1948.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 194905 | 12-Crown-4 98% | 294-93-9 | 5G | ₹11972.45 | 2022-06-14 | Buy |
| ALFA India | ALF-A11972-14 | 12-Crown-4, 98% | 294-93-9 | 25g | ₹57980 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C0858 | 12-Crown 4-Ether min. 95.0 % | 294-93-9 | 1ML | ₹3300 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C0858 | 12-Crown 4-Ether min. 95.0 % | 294-93-9 | 5ML | ₹11500 | 2022-05-26 | Buy |
12-Crown-4 Chemical Properties,Uses,Production
Chemical Properties
clear colorless to slightly yellow liquid after
Uses
12-Crown-4 can be used as:
- A promoter in the synthesis of poly(diethylsiloxane) (PDES) from monomer hexaethylcyclotrisiloxane using NaOH as a catalyst via anionic ring-opening polymerization.
- As an additive in the preparation of triarylmethane derivatives by palladium-catalyzed cross coupling reaction of aryl bromides with diarylmethane derivatives.
- A phase transfer catalyst in organic synthesis.
Definition
ChEBI: A crown ether that is cyclododecane in which the carbon atoms at positions 1, 4, 7 and 10 have been replaced by oxygen atoms.
General Description
12-Crown-4 is a crown ether generally used as a ligand in coordination chemistry. It is also known as lithium ionophore because of its strong chelating property specific to lithium cation.
Purification Methods
The distilled crude product has to be recrystallised from pentane at -20o to remove acyclic material. It is then dried over P2O5. It complexes Li. [Anet et al. Acta Chem Scand 27 3395 1973, Beilstein 19/11 V 334.]
12-Crown-4 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 224)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4535 | 58 | Inquiry |
| SANTO RIGHELLO PVT ltd | +91 9885571757 | Telangana, India | 41 | 58 | Inquiry |
| Dr. Silviu Pharmachem Pvt., Ltd. | +91-8390608382 +91-8390608382 | Mumbai, India | 248 | 58 | Inquiry |
| Dr. Silviu Pharmachem Pvt., Ltd. (DRSPL) | 91-9665522151 | Maharashtra, India | 143 | 58 | Inquiry |
| Chaturya Biotech (Tanuj Life Sciences) | 91-7702707258 | Hyderabad, India | 398 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6905 | 58 | Inquiry |
| Bhuvar Technologies | 09849396291 | Mallapur, India | 47 | 58 | Inquiry |
| Hermes Chemical Company Private Limited | +91 40 27715685 | Hyderabad, India | 15 | 58 | Inquiry |
| VASIN BIO LIFE SCIENCES PVT LTD | 9491644688 | Hyderabad, India | 2092 | 58 | Inquiry |
294-93-9(12-Crown-4)Related Search:
1,7-DIAZA-12-CROWN-4,4,10-DIAZA-12-CROWN 4-ETHER
BIS[(12-CROWN-4)METHYL] DODECYLMETHYLMALONATE
2-(HYDROXYMETHYL)-12-CROWN 4-ETHER
Tetraaza 12-crown-4
1-AZA-12-CROWN 4-ETHER,1-AZA-12-CROWN-4,AZA-12-CROWN-4,aza-12-crown-499.5+%
BENZO-12-CROWN-4,BENZO-12-CROWN 4-ETHER,Benzo-12-crown-4, 99+%,BENZO-12-CROWN-4 98+%
1-aza-12-crown-5
TETRAAZA-12-CROWN-4-1,4,7,10-TETRAACETIC ACID,TETRAAZA-12-CROWN-4 TETRAACETIC ACID AMMONIUM SALT (SEE 2923)
TETRAAZA-12-CROWN-4 TETRAHYDROCHLORIDE
CYCLODODECANE
chevron_left
1of4
chevron_right
LITHIUM IONOPHORE V
CROWN ETHER/12-CROWN-4
Eoct
Ethylene oxide cyclic tetramer
1,4,7,10-TETRAOXYCYCLODODECANE
12-CROWN-4
1,4,7,10-Tetraoxacyclododecane, 12-Crown-4
12-Crown-4,97%
CROWN ETHER/12-CROWN-4 FOR SYNTHESIS
12-Crown-4 Cyclic tetraMer of ethylene oxide which is specific for the lithiuM cation., 98%
12-Crown-4(1,4,7,10-Tetraoxacyclododecane)
12-Crown 4-Ether >
294-93-9 12-Crown-4
Crown
1,4,7,10-TETRAOXACYCLODODECANE
12-CROWN 4-ETHER
12 C 4
12C4
12-C-4
294-93-9
294-93-6
Chelation/Complexation Compounds
Macrocycles for Host-Guest Chemistry
Crown Ethers
Synthetic Reagents
Crown Ethers
Functional Materials
Macrocycles for Host-Guest Chemistry