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DOTA

DOTA Structure
CAS No.
60239-18-1
Chemical Name:
DOTA
Synonyms
TETRAXETAN;1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID;2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid;DOTA;98% DOTA;TETRAAZA;DOTADOTA;NSC 681107;DOTA, ≥97%;DOTA(M-140)
CBNumber:
CB9398467
Molecular Formula:
C16H28N4O8
Molecular Weight:
404.42
MOL File:
60239-18-1.mol
MSDS File:
SDS
Modify Date:
2024/10/29 11:48:30

DOTA Properties

Melting point 267 °C
Boiling point 701.6±60.0 °C(Predicted)
Density 1.321
storage temp. Sealed in dry,Room Temperature
solubility Water (Slightly, Heated), Methanol (Slightly)
pka 2.16±0.10(Predicted)
form Powder
color white
BRN 1186987
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
3-10-34
HS Code  29339900
NFPA 704
0
2 0

DOTA price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 86734 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid ≥97.0% (CHN) 60239-18-1 50MG ₹6386.75 2022-06-14 Buy
Sigma-Aldrich(India) 86734 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid ≥97.0% (CHN) 60239-18-1 250MG ₹22018.05 2022-06-14 Buy
TCI Chemicals (India) T1875 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid 60239-18-1 200MG ₹11900 2022-05-26 Buy
TCI Chemicals (India) T1875 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid 60239-18-1 1G ₹27000 2022-05-26 Buy
ottokemi D 9487 DOTA, ≥97% 60239-18-1 100mg ₹6939 2022-05-26 Buy
Product number Packaging Price Buy
86734 50MG ₹6386.75 Buy
86734 250MG ₹22018.05 Buy
T1875 200MG ₹11900 Buy
T1875 1G ₹27000 Buy
D 9487 100mg ₹6939 Buy

DOTA Chemical Properties,Uses,Production

Chemical Properties

Colourless crystals

Uses

Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and ther apeutic radiopharmaceuticals.

Definition

ChEBI: An azamacrocyle in which four nitrogen atoms at positions 1, 4, 7 and 10 of a twelve-membered ring are each substituted with a carboxymethyl group.

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DOTA Spectrum

TETRAAZA-12-CROWN-4 TETRAACETIC ACID AMMONIUM SALT (SEE 2923) Tetraxetan/radical 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrakisacetic acid 2,2',2'',2'''-(1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetryl)tetraacetic acid 2,2',2'',2'''-(1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetryl)tetrakisacetic acid 1,4,7,10-TETRAAZACYCLODODECANE-N,N'',N , N''-TETRAACETIC ACID , (DOTA) 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID DOTA DOTA(M-140) Tetraxetan/DOTA/1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid >=97.0% (CHN) DOTA Tetraxetan 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid 4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraacetic acid 2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane -1,4,7,10-tetrayl)tetraacetic acid(DOTA) 1,4,7,10-tetrakis(carboxymethyl)-1,4,7,10-tetraazacyclododecane Tetraxetanum (DOTA) 1,4,7,10-Tetraazacyclododecan-N,N',N,N'-tetraacetic acid TetraxetanuM 1,4,7,10-Tetraazacyclododecane-N,N',N'',N'''-tetraaceticacid,min.98%DOTA 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID, FREE ACID 1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAACETIC ACID DOTA TETRAAZA-12-CROWN-4-1,4,7,10-TETRAACETIC ACID NSC 681107 TETRAXETAN(DOTA) Atosiban impurity 9 Gadobutrol Impurity 35 DOTA, ≥97% 98% DOTA Gadobutrol Impurity 6(DOTA) DOTA60239-18-1 TETRAAZA DOTA(1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid) Gadobutrol Impurity 12 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecan-1-yl]acetic acid 2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid 2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid TETRAXETAN 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRAACETIC ACID Tritracine tetraacetic acid Gadolinium Butanol Impurity 6 Gadolinium Butanol Impurity 11 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic (3aR,4aS)-4a-(3-fluorophenyl)-1,3,3a,4a-tetrahydrocyclopropa[1,2-c]furan-1-one DOTA (TETRAXETAN) (1,4,7,10-tetra-carboxymethyl -1,4,7,10-teraaza-cyclododec -1-yl)-acetic acid(DOTA) 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid hydrate 2,2',2'',2'''-(1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid 1,4,7,10-tetraazacyclododecane-N,N’,N’’,N’’’-tetraaceticacid(DOTA) DOTADOTA Lunhuan Tengning Tetraacetic Acid 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid (DOTA) Gadolinium alcohol impurity 6 60239-18-1 60239-28-1 C16H28N4O8xH2O C16H28N4O8 Synthetic Reagents Crown Ethers