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Iodoacetic acid

Iodoacetic acid Structure
CAS No.
64-69-7
Chemical Name:
Iodoacetic acid
Synonyms
IA;iodoacetate;monoiodoacetate;iodoacetic;lodoacetic acid;MONOIODOACETIC ACID;SKL245;CH2ICOOH;iodo-aceticaci;IODOACETIC ACID
CBNumber:
CB3854071
Molecular Formula:
C2H3IO2
Molecular Weight:
185.95
MOL File:
64-69-7.mol
MSDS File:
SDS
Modify Date:
2023/9/1 16:14:28

Iodoacetic acid Properties

Melting point 79 °C
Boiling point 208°C
Density 2.2003 (estimate)
Flash point 208°C
storage temp. 2-8°C
solubility H2O: soluble, clear to hazy
form Liquid
pka 3.12(at 25℃)
color faintly yellow
Water Solubility 600 g/L (20 ºC)
Sensitive Light Sensitive
Merck 14,5025
BRN 1739079
Stability Stable. Incompatible with strong oxidizing agents, bases, strong reducing agents. Store at -20 C.
CAS DataBase Reference 64-69-7(CAS DataBase Reference)
NIST Chemistry Reference Acetic acid, iodo-(64-69-7)
EPA Substance Registry System Iodoacetic acid (64-69-7)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H314
Precautionary statements  P260-P280-P301+P310+P330-P303+P361+P353-P305+P351+P338+P310
Hazard Codes  T,C
Risk Statements  25-35
Safety Statements  22-36/37/39-45
RIDADR  UN 2923 8/PG 1
WGK Germany  1
RTECS  AI3500000
8-9
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29159080
Toxicity LD50 intravenous in dog: 45mg/kg
NFPA 704
0
3 0

Iodoacetic acid price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) I4386 Iodoacetic acid ≥98.0% (T) 64-69-7 10G ₹4373.3 2022-06-14 Buy
Sigma-Aldrich(India) I4386 Iodoacetic acid ≥98.0% (T) 64-69-7 25G ₹8779.08 2022-06-14 Buy
Sigma-Aldrich(India) I4386 Iodoacetic acid ≥98.0% (T) 64-69-7 100G ₹14711.18 2022-06-14 Buy
ottokemi I 1427 Iodoacetic acid, GR 99% 99% 64-69-7 5gm ₹2808 2022-05-26 Buy
ottokemi I 1427 Iodoacetic acid, GR 99% 99% 64-69-7 25gm ₹6705 2022-05-26 Buy
Product number Packaging Price Buy
I4386 10G ₹4373.3 Buy
I4386 25G ₹8779.08 Buy
I4386 100G ₹14711.18 Buy
I 1427 5gm ₹2808 Buy
I 1427 25gm ₹6705 Buy

Iodoacetic acid Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystalline powder

Uses

Iodoacetic acid is used as a reagent for the modification of sulfhydryl groups in organic synthesis. It reacts with cysteine moiety in proteins to prevent the re-formation of disulfide bonds during protein sequencing. It is also used as a general reagent in acylation reactions as well as in glycopeptide synthesis.

Definition

ChEBI: A haloacetic acid that is acetic acid in which one of the hydrogens of the methyl group is replaced by an iodine atom.

General Description

Colorless or white crystals.

Air & Water Reactions

May be sensitive to heat, light, and air. Water soluble

Reactivity Profile

Iodoacetic acid reacts vigorously with bases and is corrosive.

Fire Hazard

Flash point data for Iodoacetic acid are not available, but Iodoacetic acid is probably non-flammable.

Purification Methods

Crystallise it from pet ether (b 60-80o) or CHCl3/CCl4. [Beilstein 2 IV 534.]

Iodoacetic acid Preparation Products And Raw materials

Global( 161)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
GLR Innovations +91 9891111994 New Delhi, India 4542 58 Inquiry
Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5873 58 Inquiry
Central Drug House(P) Ltd. 91-11-49404040 New Delhi, India 6160 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
Omkar Speciality Chemicals Priavite Limited 09822059477 Mumbai, India 20 58 Inquiry
Hari Chemical 09411995591 Uttar Pradesh, India 1 58 Inquiry
Laksh Finechem Private Limited +91-8048600905 Gujarat, India 195 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
Hebei Mojin Biotechnology Co., Ltd +86 13288715578 +8613288715578 China 12459 58 Inquiry
iodo-aceticaci Kyselina jodoctova kyselinajodoctova RARECHEM AL BO 0101 VITAS-BB TBB000669 Aceticacid,iodo- CH2ICOOH IODOACETIC ACID MONO IODOACETIC ACID IODOACETIC ACID FREE ACID APPROX 99%,*YE LLOW POWDER IODOACETIC ACID APPROX. 99% WHITE TO OFF IODOACETIC ACID R. G. IodoaceticAcid>99% IodoaceticAcid97% IODOACETICACID,REAGENT Iodoethanoic acid Iodoacetic acid, 97% 25GR Iodoacetic acid, >=99.5% Iodiacetic acid IODOACETIC ACID, >= 98.0 % (T) Acetic acid, 2-iodo- SKL245 Iodoacetic acid, GR 99% iodoacetic monoiodoacetate MONOIODOACETIC ACID IA iodoacetate lodoacetic acid 64-69-7 ICH2COOH ICH2CO2H C2H3IO2 Synthetic Reagents Organic Building Blocks Organic Acids Puriss p.a. General Use Building Blocks Analytical Reagents Analytical Chromatography Product Catalog C1 to C5 Carboxylic Acids Carbonyl Compounds Reagents for cysteine modification Specific Amino Acid Modification Protein Modification Analytical Reagents for General Use I-N, Puriss p.a. Puriss p.a. Chemical Synthesis Organic Acids Synthetic Reagents K00001