Sodium hydroxymethanesulphinate
- CAS No.
- 149-44-0
- Chemical Name:
- Sodium hydroxymethanesulphinate
- Synonyms
- RONGALITE;SODIUM FORMALDEHYDE SULFOXYLATE;SODIUM HYDROXYMETHANESULFINATE;RONGALITE C;SODIUM FORMALDEHYDESULFOXALATE;Natriumhydroxymethansulfinat;Sodiumbisulfoxylateformaldehyde;Sodium hydroxymethanesulfinate hydrate;HYDROXYMETHANESULFINIC ACID SODIUM SALT;aldanil
- CBNumber:
- CB8773339
- Molecular Formula:
- CH3NaO3S
- Molecular Weight:
- 118.09
- MOL File:
- 149-44-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/5 20:55:42
| Melting point | ~120 °C (dec.) |
|---|---|
| Density | 1.744[at 20℃] |
| vapor pressure | 0.003Pa at 20℃ |
| Flash point | >100℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | H2O: 50 mg/mL, clear, colorless |
| form | Solid |
| color | White to Off-White |
| PH | 9.5-10.5 |
| Water Solubility | soluble H2O, alcohol [HAW93] |
| Merck | 14,8620 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| LogP | -3.4 at 22℃ |
| EPA Substance Registry System | Sodium sulfoxylate formaldehyde (anhydrous) (149-44-0) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H341-H315-H319-H335 | |||||||||
| Precautionary statements | P280-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-68-31 | |||||||||
| Safety Statements | 26-36-36/37 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | PB0380000 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 2930909899 | |||||||||
| NFPA 704 |
|
Sodium hydroxymethanesulphinate price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemicals (India) | R0053 | Sodium Hydroxymethanesulfinate Dihydrate | 149-44-0 | 500G | ₹2300 | 2022-05-26 | Buy |
| SRL | 84439 | Sodium Formaldehyde Sulfoxylate Hydrate (Rongalite) pure, 98% | 149-44-0 | 500Gms | ₹570 | 2022-05-26 | Buy |
| SRL | 11407 | Sodium Formaldehyde Sulfoxylate Hydrate (Rongalite) ExiPlus, Multi-Compendial, 98% | 149-44-0 | 500Gms | ₹690 | 2022-05-26 | Buy |
Sodium hydroxymethanesulphinate Chemical Properties,Uses,Production
Chemical Properties
white solid; used as stripping and discharge agent for textiles [HAW93]
Uses
Pharmaceutic aid (preservative).
Production Methods
Sodium formaldehyde sulfoxylate is manufactured from sodium dithionate and formaldehyde in water.
Pharmaceutical Applications
Sodium formaldehyde sulfoxylate is a water-soluble antioxidant and is generally used as the dihydrate. It is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.
Safety
The toxicological properties of sodium formaldehyde sulfoxylate
have not been fully investigated. However, it is used in the
formulation of injection products at a level to 0.1% w/v in the
final preparation administered to the patient.
Sodium formaldehyde sulfoxylate is moderately toxic by
ingestion, and when heated to decomposition it emits toxic fumes
of sulfur dioxide and sodium oxide.
LD50 (mouse, oral): 4 g/kg
LD50 (rat, IP): >2 g/kg
LD50 (rat, oral): >2 g/kg
storage
Store in well-closed, light-resistant containers at controlled room temperature (15–30℃).
Purification Methods
It crystallises from H2O as the dihydrate and decomposes at higher temperatures. Store it in a closed container in a cool place. It is insoluble in EtOH and Et2O and is a good reducing agent. [X-ray structure: Tuter J Chem Soc 3064 1955.] Note that this compound {HOCH2SO2Na} should not be confused with formaldehyde sodium bisulfite adduct {HOCH2SO3Na} from which it is prepared by reduction with Zn. [Beilstein 1 IV 3052.]
Incompatibilities
Sodium formaldehyde sulfoxylate is incompatible with strong oxidizing agents; it is decomposed by dilute acid.
Regulatory Status
Included in the FDA Inactive Ingredients Database (parenteral products up to 0.1% via the IM, IV, and SC routes). Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Sodium hydroxymethanesulphinate Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | +91-26463395 +91-7926462688 | Gujarat, India | 1615 | 58 | Inquiry |
| Rubexco Pvt Ltd | +91-9825231936 +91-9909917613 | Gujarat, India | 36 | 58 | Inquiry |
| Demosha Chemicals Pvt Ltd | +91-2222823558 +91-2222823558 | Maharashtra, India | 4 | 58 | Inquiry |
| Silox India Private Limited | +91-2652680401 +91-2652680401 | Gujarat, India | 6 | 58 | Inquiry |
| Sparchem | 91-22-62879419 | Maharashtra, India | 68 | 58 | Inquiry |
| Transpek-silox Industry Limited | 08048372524Ext 781 | Vadodara, India | 2 | 58 | Inquiry |
| Demosha Chemicals Private Limited | 07222872218 | Mumbai, India | 2 | 58 | Inquiry |
| Molychem | 08048372666Ext 559 | Mumbai, India | 577 | 58 | Inquiry |
| Titan Biotech Limited | 09711169006 | Delhi, India | 196 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| GLR Innovations | 58 |
| Rivashaa Agrotech Biopharma Pvt. Ltd. | 58 |
| Rubexco Pvt Ltd | 58 |
| Demosha Chemicals Pvt Ltd | 58 |
| Silox India Private Limited | 58 |
| Sparchem | 58 |
| Transpek-silox Industry Limited | 58 |
| Demosha Chemicals Private Limited | 58 |
| Molychem | 58 |
| Titan Biotech Limited | 58 |
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